Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07252427Recruiting
Gut bacteria in IBD with or without depression
This study looks at how the bacteria in your gut (gut microbiome) may differ between people with IBD who also have depression and those who don't. It aims to help understand the link between gut health and mood.
Jinan, ShandongAges 18 years+ - NCT07255131Recruiting
Online talk therapy for cystic fibrosis
This study tests an online cognitive behavioral therapy (a type of talk therapy) program designed for people with cystic fibrosis. It aims to help improve mental health and coping skills through 13 video sessions.
AthensAges 18–70 - NCT07264452Recruiting
Comparing two types of accelerated brain stimulation for tough depression
This study compares two fast types of brain stimulation (called accelerated theta burst stimulation) to see which works better for people whose depression hasn't improved with standard antidepressants. It's designed for people with treatment-resistant depression who are already on a stable antidepressant.
ErzurumAges 18–65 - NCT07272213Recruiting
Thyroid hormone levels, mood, and sexual health in pregnancy
This study looks at how thyroid-stimulating hormone (TSH) levels during pregnancy are linked to depression, anxiety, and sexual function in pregnant women.
Istanbul, GaziosmanpaşaAges 18–45 - NCT07276997RecruitingPhase 2
Study of Icalcaprant for major depressive disorder
This trial tests an oral medication called icalcaprant for adults with major depressive disorder (MDD). It aims to see if the drug can reduce depression symptoms and what side effects may occur.
Dothan, AlabamaAges 18–65 - NCT07284446Recruiting
Depression, memory, and outcomes in heart failure patients
This study looks at how depression and memory problems affect recovery in people hospitalized with worsening chronic heart failure. It aims to find better ways to support patients during their hospital stay.
KaunasAges 18–85 - NCT07292649Recruiting
Labor pain relief and postpartum depression risk
This study looks at how your expectations about pain relief during labor might affect your mood after giving birth. Researchers will follow you after delivery to see if there is a link between your hopes for pain management and the risk of postpartum depression.
Padova, VenetoAges 18 years+ - NCT07299903Recruiting
Sleep hygiene education study for menopausal women
This study tests if an online sleep hygiene program can improve sleep quality and reduce depression in menopausal women. It is designed for those with low sleep quality and access to a smartphone or computer.
AnkaraAges 45–60 - NCT07328373Recruiting
Depression Relapse Predictors Study
This trial looks at brain and genetic markers to understand why depression returns. It is for people with major depression who are not currently taking medication.
IstanbulAges 18–65 - NCT07679204Recruiting
Personality and life satisfaction in bipolar and depression
This study looks at how personality traits and life satisfaction affect people with bipolar II disorder or major depression. You will fill out questionnaires about your feelings and daily life.
ElâzığAges 18 years+ - NCT07638553RecruitingPhase 3
Psilocybin to prevent alcohol relapse with depression
This study tests whether psilocybin (a psychedelic compound) can help people with severe alcohol use disorder stay sober longer, especially if they also have depression. Participants receive guided psilocybin sessions alongside counseling to reduce the risk of returning to heavy drinking.
BayonneAges 18 years+ - NCT07349550Recruiting
Cognitive function, mental health, and work
This trial explores how thinking skills (like memory and focus) relate to common mental health challenges and work life. It aims to find better ways to support people with depression or anxiety who are at risk of needing sick leave.
OsloAges 18–65 - NCT07349706Recruiting
Breathing exercise for dementia risk reduction
This trial tests a simple breathing exercise done for about 5–10 minutes each day for 8 weeks. It aims to see if this exercise can reduce your risk of dementia. If you are between 60 and 80 years old and have at least one risk factor for dementia, this study may be a fit for you.
Tallahassee, FloridaAges 60–80 - NCT07369102RecruitingPhase 4
Esketamine with or without talk therapy for tough depression
This trial tests if adding a type of talk therapy called integration therapy helps esketamine work better for people with depression that hasn't improved with other treatments. You'll receive esketamine, and some people also get guided sessions to reflect on their experiences.
San JuanAges 21–65 - NCT07369557Recruiting
Mindfulness training with TMS for depression
This trial combines mindfulness training with accelerated TMS therapy for depression. It tests if adding mindfulness helps improve treatment outcomes.
Charleston, South CarolinaAges 18–80 - NCT07371988Recruiting
Talking therapy for depression in older adults
This trial tests if narrative therapy, a type of talking therapy, can help reduce depression in people aged 60 and older. If you are experiencing mild to moderate depression and visit a senior center, this therapy may give you new ways to improve your mood.
Kowloon Tong, Hong KongAges 60 years+ - NCT07372586Recruiting
Behavioral health support after ICU stay
This study tests a collaborative care model for mental health and recovery after an ICU stay. You might qualify if you visit the MUSC ICU Recovery Clinic within six months of leaving the hospital.
Charleston, South CarolinaAges 18 years+ - NCT07377682Recruiting
Trazodone for depression with mild memory problems
This study tests how well the antidepressant trazodone works in older adults with major depression and mild cognitive impairment (early memory or thinking problems). It looks at real-world results in people starting this treatment.
Lodz, PolandAges 55 years+ - NCT07382336Recruiting
Smartphone app to detect postpartum depression early
This study tests a mobile app that tracks mood changes during pregnancy to help detect postpartum depression early. If you are pregnant in your first or second trimester, can read Chinese, and have a smartphone, you may be able to join.
Hong KongAges 18 years+ - NCT07383467Recruiting
Single session help for teens with anxiety or depression
This trial offers a one-time digital self-help program for Hong Kong teens aged 12 to 17 who feel anxious or down. It aims to see if a single session can make a difference.
Hong KongAges 12–17 - NCT07384273Recruiting
Online therapy for postpartum depression symptoms
This trial tests an internet-based therapy program (iCARE) to help new mothers manage symptoms of postpartum depression. It may be a good fit if you gave birth within the last 6 months and have been feeling down or depressed.
OdenseAges 18 years+ - NCT07388004Recruiting
Comparing two group therapies for depression
This trial compares two types of group therapy for major depression: one that focuses on changing your expectations about the future, and another that helps you reconnect with rewarding activities. The goal is to see which approach works better for reducing depression symptoms.
Marburg, HesseAges 18–80 - NCT07390331Recruiting
Helping heart patients manage depression
This trial tests a program that helps patients with both depression and heart disease take a more active role in their care. It combines support for depression treatment with your regular heart checkups.
New York, New YorkAges 18 years+ - NCT07390786Recruiting
Family support program after ICU stay
This study tests a collaborative care program for family members of ICU recovery patients, designed to improve mental health support after a loved one's hospitalization.
Charleston, South CarolinaAges 18 years+
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,500 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.