Clinical trials · Tampa, FL
Depression clinical trials in Tampa
We’re tracking 31 recruiting depression studies with a site in or near Tampa — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Tampa
- NCT06968650Recruiting
Cocooned Moms Support Study
This study tests a program that offers extra support to Black women during pregnancy. It aims to help moms feel safe, connected, and healthy.
Tampa, FloridaAges 18 years+ - NCT04777357RecruitingPhase 3
Cariprazine for bipolar depression in ages 10 to 17
This Phase 3 study tests whether cariprazine can improve depression symptoms in children and teens with bipolar I disorder, and also tracks side effects. It may help if your depressive episode is ongoing and you meet specific mood and screening score requirements.
Tampa, FloridaAges 10–17 - NCT07196501RecruitingPhase 3
Study of a new add-on treatment for depression maintenance
This trial tests a new medication (NBI-1065845) added to your current antidepressant to see if it helps maintain improvement in depression. It is for people whose depression hasn't fully responded to their current oral antidepressant.
Tampa, FloridaAges 18 years+ - NCT06966401RecruitingPhase 3
Long-term safety study of a new depression treatment
This study tests a new oral medication (NBI-1065845) added to your current antidepressant to see if it's safe and tolerable over a long period for people with depression that hasn't fully responded to treatment.
Tampa, FloridaAges 18 years+ - NCT06559306RecruitingPhase 3
Seltorexant for depression with insomnia symptoms
This trial tests if adding seltorexant to your current antidepressant can improve depression and sleep problems. It is for people with major depressive disorder who still have symptoms, especially insomnia, despite trying at least one antidepressant.
Tampa, FloridaAges 18–74 - NCT07412756RecruitingPhase 3
Brenipatide for major depressive disorder
This trial tests a new medication, Brenipatide, to see if it helps people with major depression who are already on a stable treatment. You would need to inject the study drug yourself and complete questionnaires.
Tampa, FloridaAges 18–75 - NCT03887715RecruitingTeam says not enrolling
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
Tampa, FloridaAges 18 years+ - NCT06963021RecruitingPhase 3
Study of NBI-1065845 for depression that hasn't fully responded to treatment
This trial tests an investigational drug called NBI-1065845 added to your current antidepressant. It is for people with moderate to severe depression or persistent depressive disorder who have not improved enough with oral antidepressants alone.
Tampa, FloridaAges 18 years+ - NCT05922878RecruitingPhase 2
ALTO-300 study for moderate to severe depression
This trial tests ALTO-300 as an add-on treatment for people with moderate to severe major depressive disorder (MDD). It aims to see whether ALTO-300 helps improve depression symptoms when you’re already on a stable antidepressant.
Tampa, FloridaAges 18–70 - NCT06830044RecruitingPhase 3
Adding an experimental drug for major depression
This trial tests if adding a new medicine called milsaperidone can help people with major depression who haven't gotten enough relief from their current antidepressant. It aims to see if the combination works better than the antidepressant alone.
Tampa, FloridaAges 18–65 - NCT06911112RecruitingPhase 3
A new pill for depression when current treatment isn't working well enough
This trial tests an investigational medication (NBI-1065845) added to your current antidepressant to see if it can improve depressive symptoms. It is for people with moderate to severe depression who have not fully responded to their current antidepressant.
Tampa, FloridaAges 18 years+ - NCT07550166Enrolling by invitation
Mindfulness App Study for Korean Older Adults
This study tests whether a mindfulness app—guided exercises to help you relax and focus your mind—can improve wellbeing in Korean immigrants aged 60 and older. You'll use the app on your smartphone for 8 weeks.
Tampa, FloridaAges 60 years+ - NCT07592689RecruitingPhase 3
DT120 Treatment for Major Depression
This study tests whether a new medication called DT120 can help people with moderate-to-severe depression feel better. You'd take the medication for several weeks while doctors track your mood and symptoms.
Tampa, FloridaAges 18–74 - NCT07610473RecruitingPhase 2
Testing DT-101 as an add-on for depression
This trial tests if a new medication, DT-101, can help when added to your current depression treatment. It's for adults with recurrent depression who may need extra support.
Tampa, FloridaAges 18–75 - NCT06423430Recruiting
Deep brain stimulation for treatment-resistant depression (TRANSCEND)
This trial tests a new brain stimulation treatment (deep brain stimulation, or DBS) for people with hard-to-treat depression. It aims to see if targeting a specific brain area can help when other treatments have failed.
Tampa, FloridaAges 22–70 - NCT04621877Recruiting
Lay-led therapy for depression and anxiety at senior centers
This trial tests a structured, coach-led program called behavioral activation delivered in senior centers. It aims to improve symptoms of depression and generalized anxiety by teaching practical, step-by-step activity planning.
Tampa, FloridaAges 60 years+ - NCT07621237RecruitingPhase 2
TNX-102 SL for Major Depressive Disorder
This study tests whether a new medication called TNX-102 SL can reduce depression symptoms better than a placebo (inactive pill). You'll take the medication daily and have regular check-ins to see how you're doing.
Tampa, FloridaAges 18 years+ - NCT07105111RecruitingPhase 4
Valbenazine for tardive dyskinesia after other treatment
This study tests if valbenazine helps adults with tardive dyskinesia whose symptoms continue even after taking or stopping another similar medication. Tardive dyskinesia involves uncontrollable movements from long-term use of certain mental health drugs.
Tampa, FloridaAges 18 years+ - NCT06633016RecruitingPhase 2
ABX-002 for major depression (add-on treatment)
This trial tests a new medication called ABX-002 as an add-on to your current antidepressant. It's for people with moderate to severe depression who haven't gotten enough help from their current antidepressant alone.
Tampa, FloridaAges 18–65 - NCT06524830RecruitingPhase 2
Testing VLS-01 film for treatment-resistant depression
This trial tests an experimental film placed inside the cheek (VLS-01) against a placebo to see if it helps people whose depression hasn't improved with standard antidepressants. If you have tried at least two antidepressants without success, this study may be an option for you.
Tampa, FloridaAges 18–65 - NCT05850689RecruitingPhase 3
Lumateperone add-on for major depression that didn’t improve
This study tests whether adding lumateperone to an antidepressant helps adults with major depressive disorder (MDD) who haven’t improved enough after trying at least two different antidepressants. It may help reduce depressive symptoms more than antidepressants alone.
Tampa, FloridaAges 18–65 - NCT07284667RecruitingPhase 2
A new medicine for depression that hasn't improved with other treatments
This trial tests a new medicine called ACP-211 in adults with major depression who have not gotten enough relief from at least two previous antidepressants. The goal is to see if it can help when other treatments have not worked well.
Tampa, FloridaAges 18–65 - NCT07360600Recruiting
Web-based parent support program with coaching
This study tests a web-based program with brief coaching to help parents of children with disabilities manage stress and emotions. Participation involves using the program and talking with a coach, and you must have internet access and a child who visits a clinic regularly.
Tampa, FloridaAges 18 years+ - NCT07573176RecruitingPhase 3
Seltorexant for Depression in Adults and Older Adults
This study tests a new medication called seltorexant as a standalone treatment for major depression. The trial is for adults and older adults who have depression that hasn't improved with other antidepressants or who haven't tried them yet.
Tampa, FloridaAges 18–74
Hear when a new Depression trial opens near Tampa, FL
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Depression trials in other cities
Where these studies are running near Tampa
Institutions with a site for the recruiting depression studies listed above.
- Clinical Site · 5 studies
- University of South Florida · 5 studies
- K2 Medical Research · 4 studies
- IPTB Clinical Research · 3 studies
- Interventional Psychiatry of Tampa Bay · 2 studies
- Accel Research Sites - St. Pete-Largo Clinical Research Unit
- Alcanza Clinical Research
- Autobahn Site #108
What taking part in a depression study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting depression studies in Florida.
Common questions
- Are there depression clinical trials near Tampa?
- Yes. We're currently tracking 31 recruiting depression studies with a site near Tampa, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a depression study near Tampa?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Tampa to take part?
- Not necessarily. These studies have a site near Tampa, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New depression studies open near Tampa regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.