Clinical trials
Dexmedetomidine clinical trials
Below are recruiting dexmedetomidine clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05793060RecruitingPhase 4
Compare two add-on medicines for neck nerve block comfort
This study compares dexmedetomidine versus dexamethasone as “extra” medicines added to bupivacaine during an intermediate cervical plexus nerve block. It aims to see which add-on helps with pain control and smoother comfort after the procedure.
Damanhūr, El-BeheiraAges 21–60 - NCT05934669RecruitingPhase 4
Numbing medicines compared for small stitches in young children
This trial tests three medicines given through the nose to keep children comfortable during minor procedures in the emergency department, specifically for closing small cuts with stitches. It may help find which nasal medicine works best and is safest for quick, minimal procedures.
Oklahoma City, OklahomaAges 1–5 - NCT06087510RecruitingPhase 4
Different doses of esketamine and dexmedetomidine for pain after scoliosis surgery
This trial tests two different doses of esketamine and dexmedetomidine to see which provides better pain relief after scoliosis correction surgery. It aims to improve your recovery and long-term outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06138340Recruiting
How anesthesia affects brain networks in people with glioma
This study looks at how different anesthetics change brain connections during surgery for a type of brain tumor called glioma. It may help doctors choose the best anesthesia for your surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06164314Recruiting
Calming medicine during brain tumor surgery
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
BeijingAges 18 years+ - NCT06252662RecruitingPhase 4
Comparing two numbing medicines for mastectomy nerve blocks
This study compares two types of numbing medicine given through a nerve block before a mastectomy. One is a long-acting version (liposomal bupivacaine) and the other is a standard numbing medicine combined with a sedative (bupivacaine with dexmedetomidine). The goal is to see which provides better pain relief after surgery.
Portsmouth, VirginiaAges 18 years+ - NCT06545890RecruitingPhase 1/Phase 2
Ketofol vs. dexmedetomidine for preventing confusion after waking in kids having eye muscle surgery
This study compares two medicines (Ketofol and dexmedetomidine) to see which better prevents confusion and agitation when children wake up from squint eye surgery. The goal is to find a safer, more comfortable recovery for your child.
CairoAges 2–6 - NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT06579001RecruitingPhase 4
Nasal spray to prevent confusion after hip replacement
This trial tests if a nasal spray called dexmedetomidine can prevent confusion (emergence delirium) after a hip replacement. It may help older adults wake up more calmly from anesthesia.
HangzhouAges 60 years+ - NCT06619912RecruitingPhase 3
Medicine to prevent confusion after heart surgery
This trial tests if a medication called dexmedetomidine can help prevent postoperative delirium (sudden confusion and disorientation) after heart surgery. It is for adults having heart surgery with a heart-lung machine.
Xi'an, ShaanxiAges 18 years+ - NCT06636578RecruitingPhase 4
Adding dexmedetomidine to pain block for heart surgery
This study tests adding a medicine called dexmedetomidine to a standard pain-blocking injection (ropivacaine) used during heart surgery. The goal is to see if it reduces pain and speeds recovery better than the injection alone.
Al FayyumAges 20–65 - NCT06665438RecruitingPhase 3
Pain relief after knee arthroscopy: numbing injection with added medication
This trial tests whether adding dexmedetomidine to a numbing injection (bupivacaine) inside the knee joint provides better pain relief after arthroscopic ACL reconstruction. It aims to help patients recover more comfortably after surgery.
AsyutAges 18–65 - NCT06702488RecruitingPhase 1
Dexmedetomidine and magnesium to protect thinking after surgery in seniors
This study tests whether adding two drugs, dexmedetomidine and magnesium sulfate, during anesthesia can help older adults keep their thinking and memory sharp after open abdominal surgery. It aims to reduce the risk of confusion or memory problems that sometimes happen after surgery.
Al FayyumAges 60–80 - NCT06281977RecruitingPhase 3
Dexmedetomidine for electrical storm in the ICU
This trial tests if a medication called dexmedetomidine (a sedative that can also stabilize heart rhythm) helps calm electrical storms—dangerous, repeated episodes of fast heartbeats. It is for people in the intensive care unit who are experiencing this emergency.
Rochester, MinnesotaAges 18 years+ - NCT06712186RecruitingPhase 1/Phase 2
Dexmedetomidine for safer intubation in high blood pressure patients
This study tests if dexmedetomidine can help prevent dangerous blood pressure spikes during breathing tube placement for surgery in patients with high blood pressure. It is for older adults (over 60) who have been managing their hypertension for at least 6 months.
Karachi, SindhAges 60 years+ - NCT06736483RecruitingPhase 2
Dexmedetomidine for children’s groin surgery recovery
This trial tests whether adding a sedative called dexmedetomidine to a numbing shot (nerve block) helps children aged 1–7 recover better after groin surgery. The goal is to improve comfort and reduce side effects.
Montpellier, FranceAges 1–7 - NCT06740903RecruitingPhase 2/Phase 3
Comparing two drugs for pain control in gallbladder surgery
This study compares two medications, dexmedetomidine and lignocaine, to see which works better for pain management during and after laparoscopic gallbladder removal. It may help improve comfort and recovery for people having this surgery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT06759116Recruiting
Comparing two pain medicines for knee surgery recovery
This trial tests whether adding fentanyl or dexmedetomidine to a standard numbing medicine (bupivacaine) provides better pain relief after knee surgery. It may help find the best option for patients undergoing knee procedures like total knee replacement or ACL repair.
El SharkiaAges 21–85 - NCT06778811RecruitingPhase 4
Sleep quality study for heart surgery patients
This trial studies sleep problems before and after heart surgery. It tests two medicines to see if they can help improve sleep. This may help you recover better after surgery.
Nanjing, JiangsuAges 40–75 - NCT06779604Recruiting
Numbing medicine mix for arm surgery pain relief
This trial tests if adding two medicines, dexmedetomidine and dexamethasone, to the numbing shot around the arm's nerves can improve pain relief during and after upper arm or hand surgery.
Istanbul, UmraniyeAges 18–70 - NCT06899841RecruitingPhase 2/Phase 3
Dexmedetomidine in a nerve block for kidney stone surgery
This study tests whether adding a medicine called dexmedetomidine to a nerve block (an injection near the spine) can improve pain relief after kidney stone surgery. It is for people who are generally healthy and scheduled for a kidney stone procedure.
Asyut, Assiut GovernorateAges 18–70 - NCT06978192RecruitingPhase 2
Study for treating shingles pain with a special nerve block
This trial tests a combination of two treatments to reduce shingles pain that hasn't responded to standard medicines. It involves a nerve block to see if it can help people who have ongoing pain after shingles.
Zunyi, GuizhouAges 40–85 - NCT06979141RecruitingPhase 3
Cough prevention after general anesthesia
This trial compares three drugs (dexmedetomidine, magnesium sulfate, and lidocaine) to see which best prevents coughing when waking up from anesthesia. It is for adults between 21 and 60 who are having surgery and are in good general health.
AsyutAges 21–60 - NCT07002723Recruiting
Esketamine and dexmedetomidine for better sleep after hip surgery
This study tests whether combining two medicines (esketamine and dexmedetomidine) can improve sleep quality after hip fracture surgery in older adults. The goal is to help you rest better and recover more comfortably.
Shenzhen, GuangdongAges 65 years+
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Common questions
- Are there clinical trials for dexmedetomidine?
- Yes. Clin2 currently lists 194 recruiting dexmedetomidine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dexmedetomidine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dexmedetomidine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.