Clinical trials
Dexmedetomidine clinical trials
Below are recruiting dexmedetomidine clinical trials, each written for real people, not researchers. We’re tracking 178 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07290595RecruitingPhase 2/Phase 3
Comparing two medicines for faster nerve block in arm surgery
This study compares two medicines (dexmedetomidine and dexamethasone) added to a numbing drug (ropivacaine) for a nerve block in the collarbone area. The goal is to see which combination works faster and better for pain relief during upper limb surgery.
Sāhīwāl, Punjab ProvinceAges 18–70 - NCT07285083Recruiting
Pain relief after abdominal surgery: comparing two numbing medicines
This study compares two numbing medicines (bupivacaine alone vs. bupivacaine plus dexmedetomidine) to see which provides better pain relief after abdominal surgery. If you are having a planned abdominal operation, this trial may help improve your recovery comfort.
Rahim Yar Khan, Punjab ProvinceAges 21–45 - NCT07271147Recruiting
Nerve stimulation plus sedative for post-op nausea
This study tests whether combining a very mild nerve stimulation (taVNS) with a sedative (dexmedetomidine) can reduce nausea and vomiting after laparoscopic surgery. It may be a good option if you are scheduled for keyhole surgery and want to feel better afterward.
Nantong, JiangsuAges 18–65 - NCT06899841RecruitingPhase 2/Phase 3
Dexmedetomidine in a nerve block for kidney stone surgery
This study tests whether adding a medicine called dexmedetomidine to a nerve block (an injection near the spine) can improve pain relief after kidney stone surgery. It is for people who are generally healthy and scheduled for a kidney stone procedure.
Asyut, Assiut GovernorateAges 18–70 - NCT07239479Recruiting
Dexmedetomidine and desflurane for laparoscopic colon surgery
This study tests a combination of two drugs (dexmedetomidine and desflurane) used during keyhole colon surgery to see if it helps with recovery. It is designed for generally healthy adults having a planned laparoscopic colectomy.
Ho Chi Minh City, Ho Chi MinhAges 18–65 - NCT06665438RecruitingPhase 3
Pain relief after knee arthroscopy: numbing injection with added medication
This trial tests whether adding dexmedetomidine to a numbing injection (bupivacaine) inside the knee joint provides better pain relief after arthroscopic ACL reconstruction. It aims to help patients recover more comfortably after surgery.
AsyutAges 18–65 - NCT07180940RecruitingPhase 4
Comparing two medicines added to a nerve block for back surgery
This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.
PoznanAges 18 years+ - NCT07168720RecruitingPhase 2
Dexmedetomidine patch for calming children before surgery
This study tests a skin patch that helps children relax before surgery. The patch contains a medicine that is absorbed through the skin to reduce anxiety, so the child may need less anesthesia.
Guangzhou, GuangdongAges 2–6 - NCT07144007Recruiting
Preventing agitation after rhinoplasty with propofol and dexmedetomidine
This study tests whether giving two medicines, propofol and dexmedetomidine, during rhinoplasty can help prevent confusion or restlessness when waking up from anesthesia. It may be a good option if you are having nose surgery and are generally healthy.
Van, TuşbaAges 18–65 - NCT07125573Enrolling by invitation
Esketamine and dexmedetomidine for recovery after lung surgery
This trial tests if adding two medicines (esketamine and dexmedetomidine) during your thoracoscopic (keyhole) lung surgery helps you recover better and feel less discomfort afterward.
Kunming, YunnanAges 18–65 - NCT06970626RecruitingPhase 2/Phase 3
Comparing pain relief methods after sleeve gastrectomy
This study compares two ways to manage pain after laparoscopic sleeve gastrectomy: one uses a medication called dexmedetomidine given through an IV, and the other uses a combination of nerve blocks (TAP block and paragastric block) to see which leads to a better recovery.
AlexandriaAges 20–60 - NCT06970678RecruitingPhase 1/Phase 2
A new way to ease pain and speed recovery after sleeve gastrectomy
This study tests whether adding two pain-management methods—a sedative infusion and a nerve block around the stomach—can help you recover faster and more comfortably after sleeve gastrectomy surgery. If you're eligible, you'll receive the extra treatment on top of standard anesthesia.
AlexandriaAges 18–60 - NCT07088900Recruiting
Dexmedetomidine with bupivacaine for pain relief in children's appendix surgery
This trial tests if adding dexmedetomidine to bupivacaine (a numbing medicine given near the tailbone) provides better pain relief during and after appendix surgery in children. It may help reduce the need for other pain medicines.
CairoAges 2–7 - NCT07080229RecruitingPhase 3
Nasal spray for blood pressure during cataract surgery in older adults
This trial tests whether a nasal spray of dexmedetomidine can help control blood pressure in older adults with high blood pressure who are having cataract surgery. It may keep your blood pressure more stable during the procedure.
Ismailia, Ismailia GovernorateAges 65 years+ - NCT06978192RecruitingPhase 2
Study for treating shingles pain with a special nerve block
This trial tests a combination of two treatments to reduce shingles pain that hasn't responded to standard medicines. It involves a nerve block to see if it can help people who have ongoing pain after shingles.
Zunyi, GuizhouAges 40–85 - NCT07056582Recruiting
Pain relief before nasal surgery: ketamine vs. dexmedetomidine
This trial tests two inhaled medicines given before surgery to see which one works better for pain after nasal surgery. One medicine is ketamine and the other is dexmedetomidine, both given as a mist through a nebulizer.
SohagAges 20–60 - NCT07056244Recruiting
Comparing two pain medicines for children’s hernia surgery
This study tests whether adding dexmedetomidine or dexamethasone to the standard numbing medicine (bupivacaine) provides better pain relief for children getting hernia surgery. The medicine is given through a shot in the lower back (caudal epidural block) to help keep your child comfortable during and after the operation.
SohagAges 2–6 - NCT07034898Enrolling by invitationPhase 4
Dexmedetomidine vs Labetalol for Airway Stress in Brain Surgery
This trial compares two medicines (dexmedetomidine and labetalol) to see which one better controls stress on the airway during brain surgery in people with high blood pressure. The goal is to find a safer way to manage your heart rate and blood pressure while you are under anesthesia.
CairoAges 30–60 - NCT07034300RecruitingPhase 4
Comparing lidocaine with and without dexmedetomidine for arm surgery
This trial tests whether adding dexmedetomidine to lidocaine works better for numbing the arm during surgery. Patients get numbing medicine through a special IV in the arm while the surgery is happening.
Lahore, Punjab ProvinceAges 18–60 - NCT07023991Enrolling by invitationPhase 1
Dexmedetomidine with bupivacaine for children's lower abdominal surgery
This trial tests whether adding dexmedetomidine (a sedative) to bupivacaine (a numbing medicine) improves pain relief from a nerve block in young children having lower belly surgery. The goal is to see if the combination provides better or longer-lasting pain control.
Cairo, EgyptAges 1–7 - NCT07022821RecruitingPhase 4
Comparing two pain medicines after planned C-section
This study tests two medications, dexmedetomidine and ketamine, to see which one works better for pain after a planned C-section. If you're having a scheduled C-section and are generally healthy, this trial could help find better pain relief options.
Lahore, Punjab ProvinceAges 18–50 - NCT07013955Enrolling by invitationPhase 3
Comparing nasal packing drugs for better sinus surgery view
This trial is testing whether packing the nose with one of three medications (dexmedetomidine, midazolam, or bupivacaine) during functional endoscopic sinus surgery (FESS) can improve the surgeon's view during the procedure. It may help patients by reducing bleeding and making the surgery smoother.
MinyaAges 16–60 - NCT07002723Recruiting
Esketamine and dexmedetomidine for better sleep after hip surgery
This study tests whether combining two medicines (esketamine and dexmedetomidine) can improve sleep quality after hip fracture surgery in older adults. The goal is to help you rest better and recover more comfortably.
Shenzhen, GuangdongAges 65 years+ - NCT06979141RecruitingPhase 3
Cough prevention after general anesthesia
This trial compares three drugs (dexmedetomidine, magnesium sulfate, and lidocaine) to see which best prevents coughing when waking up from anesthesia. It is for adults between 21 and 60 who are having surgery and are in good general health.
AsyutAges 21–60
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Common questions
- Are there clinical trials for dexmedetomidine?
- Yes. Clin2 currently lists 178 recruiting dexmedetomidine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dexmedetomidine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dexmedetomidine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.