Clinical trials
Dexmedetomidine clinical trials
Below are recruiting dexmedetomidine clinical trials, each written for real people, not researchers. We’re tracking 192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07502651Enrolling by invitationEarly Phase 1
Comparing two sedatives for jaw fracture surgery
This trial tests two medications given as a nasal spray to help you relax during surgery for a broken jaw. The goal is to see which one works better and is safer.
Rohtak, HaryanaAges 18–50 - NCT07677917Enrolling by invitationPhase 1
Medicine to reduce restlessness after sinus surgery
This trial tests two inhaled medicines, dexmedetomidine and magnesium sulfate, to see which is better at preventing agitation and restlessness as patients wake up from functional endoscopic sinus surgery. It may help you recover more calmly.
CairoAges 21–50 - NCT07509866Recruiting
Comparing pain relief options for knee replacement surgery
This trial tests two different numbing medicines for knee replacement surgery. It compares a long-acting numbing medicine (liposomal bupivacaine) with a standard one (ropivacaine) mixed with other drugs to see which provides better pain control. The goal is to find a way to reduce pain and improve recovery.
Wuhan, HubeiAges 18–80 - NCT07519863RecruitingPhase 2
Comparing sedation medicines for burned children during procedures
This study tests two different sedation medicine combinations to see which one reduces confusion and agitation (called delirium) when children with burn injuries need procedures done. The goal is to find the safest, most comfortable option for your child during treatment.
CairoAges 3–16 - NCT06641206Recruiting
Dexmedetomidine injection for chronic knee pain
This trial tests whether a single injection of dexmedetomidine into the knee joint can reduce chronic knee pain. It is for people who are not scheduled for knee surgery and have no serious health problems.
Tanta, El GharbyiaAges 40–75 - NCT07365800Enrolling by invitationPhase 4
Combination pain control after complex spine surgery
This study tests a combination of three medications (methadone, dexmedetomidine, and ketamine) to control pain after major spine surgery. If you are having complex spine surgery, this trial may offer better pain relief without needing as much opioid medication.
Columbia, MissouriAges 18–79 - NCT07363681Recruiting
Comparing Two Anesthesia Methods for Urological Surgery
This study compares two types of anesthesia during urological surgery: inhaled gases versus a medicine called dexmedetomidine. The goal is to see which one helps you recover more smoothly in the recovery room.
Istanbul, IstanbulAges 39–99 - NCT06490731RecruitingPhase 1/Phase 2
Comparing two sedatives for ICU recovery after bowel surgery
This trial tests whether dexmedetomidine or ketamine is better at reducing inflammation and keeping blood pressure stable in patients recovering from emergency abdominal surgery. It may help doctors choose the best sedation for you after surgery.
AsyutAges 18–70 - NCT06480539RecruitingPhase 4
Dexmedetomidine for Better Sleep After Lung Surgery in Older Adults
This study tests whether giving a medicine called dexmedetomidine at night can help older adults sleep better and feel less tired after lung surgery. If you are 60 or older and having lung surgery through small cuts (thoracoscopy), you may be able to join.
Genk, LimburgAges 60 years+ - NCT07013955Enrolling by invitationPhase 3
Comparing nasal packing drugs for better sinus surgery view
This trial is testing whether packing the nose with one of three medications (dexmedetomidine, midazolam, or bupivacaine) during functional endoscopic sinus surgery (FESS) can improve the surgeon's view during the procedure. It may help patients by reducing bleeding and making the surgery smoother.
MinyaAges 16–60 - NCT06878703RecruitingPhase 3
Dexmedetomidine vs midazolam for preterm babies on a ventilator
This study compares two sedative medicines, dexmedetomidine and midazolam, to see which one helps preterm babies on a ventilator breathe on their own sooner. Your baby may be eligible if they were born very early and need medicine to relax while on the breathing machine.
ParisAges Up to 7 months - NCT06808295RecruitingPhase 1
Dexmedetomidine for tear duct surgery
This study tests whether a medication called dexmedetomidine can reduce the amount of anesthesia needed during tear duct surgery (DCR), possibly making the procedure safer and more comfortable.
GizaAges 16–75 - NCT06741566RecruitingEarly Phase 1
Nasal spray before heart bypass to protect memory
This study tests whether a nasal spray containing dexmedetomidine or insulin, given before heart bypass surgery, can help prevent memory and thinking problems that sometimes happen after the operation. It is for adults 60 and older.
Al FayyumAges 60–75 - NCT06970678RecruitingPhase 1/Phase 2
A new way to ease pain and speed recovery after sleeve gastrectomy
This study tests whether adding two pain-management methods—a sedative infusion and a nerve block around the stomach—can help you recover faster and more comfortably after sleeve gastrectomy surgery. If you're eligible, you'll receive the extra treatment on top of standard anesthesia.
AlexandriaAges 18–60 - NCT07316166RecruitingPhase 4
Nerve Block With or Without Extra Medicine for Hip Replacement
This trial compares two types of nerve blocks for pain relief after total hip replacement. One block uses a standard numbing medicine, and the other adds a medication (dexmedetomidine) that may extend the pain relief. The goal is to see which approach works better for managing pain after surgery.
Providence, Rhode IslandAges 18–80 - NCT07532733Recruiting
Sedation Safety During Minimally Invasive Heart Valve Procedure
This study examines how a specific sedative medication (dexmedetomidine) affects breathing and heart function during a minimally invasive procedure to replace a faulty heart valve. Researchers want to ensure the sedation is safe and effective for older adults.
BrusselsAges 60 years+ - NCT06067893Enrolling by invitationPhase 4
Low dose sedation medicine for pain after scoliosis surgery
This trial tests a low dose of a sedative medicine, dexmedetomidine, given during and after spine surgery to see if it helps with pain. It is for teens and adults with scoliosis having back fusion surgery.
Kansas City, MissouriAges 10–21 - NCT04824144RecruitingPhase 1/Phase 2
Dexmedetomidine for agitation in palliative care delirium
This trial tests whether dexmedetomidine can help calm agitation caused by delirium in adults receiving palliative (comfort-focused) care. It may help reduce restlessness and distress when standard approaches may not be enough.
Calgary, AlbertaAges 18 years+ - NCT04912518Recruiting
Dexmedetomidine for heart protection after a specific heart attack
This study tests whether dexmedetomidine can protect the heart in people who are having a specific type of heart attack (anterior STEMI) when treated within 6 hours of symptom start. You may be considered if your diagnosis and vital signs fit the study safety rules, and if you can take part in follow-up.
Hefei, AnhuiAges 18–75 - NCT04916197RecruitingPhase 4
Dexmedetomidine sedation after stroke clot removal
This Phase 4 study tests whether using a specific calming medicine (dexmedetomidine) for a longer period after a successful clot-removal procedure helps people do better in the long term. It may help improve outcomes after ischemic stroke where the clot is successfully treated.
Beijing, Beijing MunicipalityAges 18–80 - NCT04928300RecruitingPhase 3
Low-dose pain medicine vs saline for broken ribs
This Phase 3 study tests whether low-dose dexmedetomidine (a calming/pain-related medicine used during anesthesia or ICU care) works better than normal saline to reduce hard-to-control rib fracture pain. It may help people with multiple broken ribs who still have significant pain despite other treatments.
Asyut, AssuitAges 18–65 - NCT05303987RecruitingPhase 2
Dexmedetomidine or propofol for sleep endoscopy in children
This Phase 2 study compares two medicines used to help children sleep during a procedure called drug-induced sleep endoscopy. It’s for children with obstructive sleep apnea who are being evaluated before adenotonsillectomy, to help surgeons understand the cause of the blockage and potentially improve treatment planning.
Ann Arbor, MichiganAges 3–11 - NCT05793060RecruitingPhase 4
Compare two add-on medicines for neck nerve block comfort
This study compares dexmedetomidine versus dexamethasone as “extra” medicines added to bupivacaine during an intermediate cervical plexus nerve block. It aims to see which add-on helps with pain control and smoother comfort after the procedure.
Damanhūr, El-BeheiraAges 21–60 - NCT05934669RecruitingPhase 4
Numbing medicines compared for small stitches in young children
This trial tests three medicines given through the nose to keep children comfortable during minor procedures in the emergency department, specifically for closing small cuts with stitches. It may help find which nasal medicine works best and is safest for quick, minimal procedures.
Oklahoma City, OklahomaAges 1–5
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Common questions
- Are there clinical trials for dexmedetomidine?
- Yes. Clin2 currently lists 192 recruiting dexmedetomidine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dexmedetomidine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dexmedetomidine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.