Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06692712RecruitingPhase 3
Gene therapy study for children with SPG50
This study tests a gene therapy called IT MELPIDA for children with SPG50, a genetic condition that affects movement and development. The treatment is given through a lumbar puncture (spinal tap) and aims to slow or stop the loss of motor skills.
Dallas, TexasAges 4 months–6 years - NCT06361108RecruitingPhase 1
Spray study for diabetic nerve pain in feet
This study tests a new spray medication (YJ001) applied to the feet to see if it is safe and helps reduce pain in people with diabetic peripheral neuropathy. You may qualify if you have diabetes, stable blood sugar, and moderate to severe nerve pain in your feet.
Fredericksburg, TexasAges 18–80 - NCT06492460RecruitingPhase 3
Two courses of chemo-radiation after surgery for high-risk head and neck cancer
This trial tests whether giving two rounds of cisplatin chemo along with radiation after surgery can help people with high-risk head and neck squamous cell carcinoma. It is for patients who have already had surgery and whose cancer showed signs of being more aggressive.
Guangzhou, GuangdongAges 18–70 - NCT06672536RecruitingPhase 1/Phase 2
Study of SCT520FF for wet age-related macular degeneration
This trial tests an investigational drug called SCT520FF for people with wet age-related macular degeneration (nAMD). It aims to find the safest dose and check if it can improve vision. You may be eligible if you have active new blood vessels in your eye from nAMD and have not had certain other eye problems.
TianjingAges 45–80 - NCT06681012Recruiting
Gelsectan for irritable bowel syndrome with diarrhea
This trial tests a supplement called Gelsectan to see if it reduces diarrhea and belly pain in people with diarrhea-predominant irritable bowel syndrome (IBS-D). It may help if you have loose, urgent stools more often than not.
LeuvenAges 18–65 - NCT06680232RecruitingPhase 1
Gene therapy trial for chronic hepatitis B
This trial tests a gene therapy called PBGENE-HBV for people with chronic hepatitis B who are already on antiviral treatment. The goal is to see if it is safe and can help control the virus.
Boston, MassachusettsAges 18–70 - NCT06675617Recruiting
Additional stent for type B aortic dissection treatment
This trial tests a new device, called the Allay aortic stent, that is used along with a standard stent graft to treat a type B aortic dissection (a tear in the aorta). The goal is to improve how the aorta heals and reduce complications. It is for people whose dissection extends into the abdomen and are already planned for stent grafting.
SalzburgAges 18 years+ - NCT06662786RecruitingPhase 3
Amivantamab plus chemo vs. standard chemo for left-sided colorectal cancer
This trial compares a new combination (amivantamab plus chemotherapy) with the standard treatment (cetuximab plus chemotherapy) as the first therapy for people with left-sided colorectal cancer that has spread. The goal is to see which approach works better when the tumor has no mutations in the KRAS, NRAS, or BRAF genes.
Gilbert, ArizonaAges 18 years+ - NCT06666283RecruitingPhase 1
Testing a new drug for diabetic kidney disease
This study tests a new medicine called AP303 for people with type 2 diabetes and chronic kidney disease. The goal is to see if it is safe and how the body processes it. If you have diabetes and your kidneys are not working as well as they used to, this trial might help find new treatment options.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06374368Recruiting
Small bowel diversion surgery for obesity
This trial tests a surgery called small bowel diversion to help people with obesity lose weight. It may also improve blood sugar control for those with type 2 diabetes.
OstravaAges 18–65 - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06635629RecruitingPhase 2
Desmopressin test for ACTH-dependent Cushing syndrome
This trial studies how well a desmopressin stimulation test works to diagnose ACTH-dependent Cushing syndrome. It compares results from people with possible or recurrent Cushing syndrome and healthy volunteers.
Bethesda, MarylandAges 18–70 - NCT06629649Recruiting
AI-based glaucoma screening at health centers
This trial uses an AI tool to screen for glaucoma at community health centers. If you qualify, you will get a free eye check to catch glaucoma early and help researchers improve screening for high-risk groups.
Birmingham, AlabamaAges 18 years+ - NCT06621979Recruiting
Study of fundoplicature after omega gastric bypass
This study checks if a second surgery to wrap the top of the stomach (fundoplicature) works well for people who had severe heartburn after a specific type of gastric bypass. If you had this second surgery in the last 2 years and your heartburn is better, you may be eligible.
CornebarrieuAges 18 years+ - NCT06616844Recruiting
Patch for non-healing diabetic foot ulcers
This trial tests a special patch made from pig tissue (placenta) placed on diabetic foot ulcers that are not healing well. If you have a foot ulcer that has been present for 4 to 52 weeks and is not shrinking, you may be able to join the study.
Fresno, CaliforniaAges 18 years+ - NCT06592274RecruitingPhase 2
Study of HB0017 for people with plaque psoriasis
This trial tests an investigational drug, HB0017, in adults with moderate to severe plaque psoriasis. If you have had psoriasis for at least 6 months and have not used certain biologic treatments, you may be able to join.
Bengbu, AnhuiAges 18–75 - NCT06597942RecruitingPhase 1/Phase 2
Brain stimulation for Alzheimer's disease
This study tests whether a new type of brain stimulation (called repetitive transcranial magnetic stimulation, or rTMS) with a larger coil can improve memory and thinking in people with mild to moderate Alzheimer's disease. It involves multiple sessions of rTMS and MRI scans.
Los Angeles, CaliforniaAges 55–100 - NCT06422741Recruiting
Grape seed extract for cholesterol in night shift workers
This study tests whether a grape seed extract supplement can help lower LDL (bad) cholesterol in people who work rotating night shifts. It is looking for healthy adults with moderately high cholesterol who are not taking cholesterol medicine.
Reus, TarragonaAges 18 years+ - NCT06577467Recruiting
Studying leftover virus after covid recovery
This study looks for signs of leftover SARS-CoV-2 virus in people who have fully recovered from COVID-19, including those with ongoing neurological symptoms (like brain fog, fatigue, or nerve pain). It aims to understand why some people have long-lasting symptoms after infection.
Bethesda, MarylandAges 18–110 - NCT06582017RecruitingPhase 1
Study of QXL138AM for advanced solid tumors and multiple myeloma
This trial tests an investigational drug called QXL138AM for people with advanced solid tumors or multiple myeloma that has not responded to standard treatments. The goal is to see if the drug is safe and effective.
Los Angeles, CaliforniaAges 18 years+ - NCT06571487Recruiting
Growth hormone resistance in beta cells after pregnancy
This study looks at how the body's insulin-making cells (beta cells) might become resistant to growth hormone after a full-term pregnancy. It compares women who had gestational diabetes to those who didn't, to learn more about diabetes risk. You may join if you had a healthy single-baby pregnancy in the last 5 years and never had type 1 or type 2 diabetes.
Columbia, MissouriAges 18–45 - NCT06583083RecruitingPhase 2
Sintilimab plus chemo vs chemo alone for advanced ENKTL lymphoma
This trial tests whether adding the immunotherapy drug sintilimab to a standard chemotherapy regimen (P-GEMOX) works better than chemotherapy alone for people with advanced ENKTL lymphoma. The goal is to see if the combination improves outcomes.
Guangzhou, GuangdongAges 18 years+ - NCT06567314RecruitingPhase 2
Study of Ivonescimab for advanced skin or prostate cancer
This study tests a new immunotherapy medicine, ivonescimab, in people with advanced skin cancer or advanced prostate cancer. It looks at how safe and effective the drug is.
Houston, TexasAges 18 years+ - NCT06552169RecruitingPhase 2
Treg cell therapy to lower anti-rejection meds after kidney transplant
This trial tests whether adding a special type of immune cell (Treg cells) to standard therapy can help kidney transplant recipients safely take lower doses of anti-rejection medicines. It is for people who are getting a kidney from a living donor.
Phoenix, ArizonaAges 18–65
Hear when a new Diabetes (Insulin-requiring, Type 1 or Type 2) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,152 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.