Clinical trials · California
Diabetes clinical trials in California
We’re tracking 189 recruiting diabetes studies with a site in California — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Palo Alto, CaliforniaAges 12 years+ - NCT06662994RecruitingPhase 4
High dose aflibercept for diabetic macular edema after vitrectomy
This trial tests a high-dose version of the drug aflibercept (given as an eye injection) for people with diabetic macular edema who have previously had a vitrectomy surgery. The goal is to see if this higher dose can help reduce swelling and improve vision.
Fullerton, CaliforniaAges 21 years+ - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Los Angeles, CaliforniaAges 10–17 - NCT06654713Recruiting
Closed-loop insulin system impact on pregnancy study
This study looks at how automated insulin delivery systems (closed-loop pumps) work during pregnancy for women with type 1 diabetes. It aims to understand how these systems can help manage blood sugar levels safely for both you and your baby.
San Francisco, CaliforniaAges 18 years+ - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
San Diego, CaliforniaAges 18–50 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Fresno, CaliforniaAges 18–80 - NCT06619860RecruitingPhase 2
VX-993 for diabetic nerve pain
This trial tests a new medicine called VX-993 for people with diabetes who have had nerve pain in both feet or legs for at least a year. The goal is to see if it reduces pain and is safe.
Bakersfield, CaliforniaAges 18–80 - NCT06524960RecruitingPhase 1/Phase 2
Denosumab for Preserving Insulin in Type 1 Diabetes
This study tests if denosumab, a drug normally used for bone health, can help preserve your body's own insulin production in type 1 diabetes. It might slow the loss of insulin-making cells, helping you maintain better blood sugar control over time.
Duarte, CaliforniaAges 18–50 - NCT06525259Recruiting
Study on risk factors for type 2 diabetes in youth
This study looks for children and teens who are at high risk of developing type 2 diabetes to understand what factors lead to it. If your child is overweight, has slightly high blood sugar, and is in early to mid-puberty, they may be able to join.
Los Angeles, CaliforniaAges 8–15 - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Los Angeles, CaliforniaAges Any age - NCT06445946RecruitingPhase 4
Metformin vs insulin for gestational diabetes
This study compares two common medicines (metformin pills and insulin shots) to see which works better for controlling blood sugar in pregnant women with gestational diabetes. The goal is to find the best treatment for both mom and baby, now and in the long term.
Los Angeles, CaliforniaAges 18 years+ - NCT06453928Recruiting
Starting diabetes technology for type 1 diabetes
This study helps people with type 1 diabetes who use insulin injections learn about and start using diabetes technology like continuous glucose monitors or insulin pumps. It aims to see if starting technology improves blood sugar control.
Torrance, CaliforniaAges 18 years+ - NCT06408207Recruiting
CGM Academy for Youth with Type 1 Diabetes
This study tests a program to help young people with type 1 diabetes learn to use continuous glucose monitors (CGMs) like Dexcom G6 and G7. It aims to improve diabetes management through education and support.
Los Angeles, CaliforniaAges 8–18 - NCT06329375Recruiting
Food Help for Diabetes Patients After Hospital Stay
This study helps people with diabetes who are admitted to Stanford Hospital and have trouble affording enough food. It provides meals through Mom's Meals after you go home, to make sure you have healthy food options.
Palo Alto, CaliforniaAges 18 years+ - NCT06296485Recruiting
Safer Aging with Diabetes Monitoring
This study tests a way to help older adults with type 2 diabetes who use insulin avoid dangerously low blood sugar. You would use a continuous glucose monitor and get support via email or internet to stay safe.
Fremont, CaliforniaAges 75 years+ - NCT06251323Recruiting
Better diabetes care with team support and technology
This study tests a new way to help adults with type 2 diabetes get better care. It includes a team of healthcare providers and uses technology to support your treatment.
Stanford, CaliforniaAges 18 years+ - NCT06002048Enrolling by invitation
AI Study for Diabetes Insights
This study uses artificial intelligence to better understand type 2 diabetes. It is open to adults with or without type 2 diabetes, and aims to improve care for everyone.
San Diego, CaliforniaAges 40–85 - NCT05138432Recruiting
More fresh fruit and vegetables for kids with type 2 diabetes
This study tests whether giving families extra fresh fruits and vegetables helps children manage type 2 diabetes. It’s delivered through a “prescription” program and may support healthier eating habits.
San Diego, CaliforniaAges Up to 18 years - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Escondido, CaliforniaAges 18–75 - NCT05758545Recruiting
Device treatment for diabetic foot ulcers with poor blood flow
This trial tests whether COMS One is safe and effective for healing a specific diabetic foot ulcer. It may help people whose ulcer is not healing well, especially when blood flow to the foot is limited.
Castro Valley, CaliforniaAges 22–90 - NCT05752292Enrolling by invitation
Pregnant with gestational diabetes: share risk info to help
This study is testing how to share risk information during pregnancy in a way that helps patients feel more informed and empowered. It includes people currently pregnant with gestational diabetes and will ask about your preferences and understanding.
Pleasanton, CaliforniaAges 18 years+ - NCT05704309Enrolling by invitation
Study of diabetes prevention participants using brain scans
This study looks at how people who previously took part in a diabetes prevention program are doing over time, including brain health using MRI scans for some participants. It may help researchers understand who is at higher risk for memory and thinking problems and why.
Alhambra, CaliforniaAges Any age - NCT05505669Recruiting
Blood test study to track markers in diabetes
This study measures “circulating biomarkers” (blood-based signals) in people with type 1 or type 2 diabetes, and in some people without diabetes who test positive for certain diabetes antibodies. The goal is to understand what these blood signals can tell us about diabetes development and progression.
Duarte, CaliforniaAges Any age
Diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting diabetes studies listed above.
- University of California, San Francisco · 3 studies
- Children's Hospital Los Angeles · 2 studies
- City of Hope · 2 studies
- Stanford University · 2 studies
- University of California San Diego · 2 studies
- Angel City Research
- Angel City Research, Inc.
- Board of Trustees of the Leland Stanford Junior University
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in California?
- Yes. We're currently tracking 189 recruiting diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.