Clinical trials · California
Diabetes clinical trials in California
We’re tracking 189 recruiting diabetes studies with a site in California — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06770933RecruitingPhase 2
VX-01 pill for diabetic eye disease study
This trial tests if an oral medication called VX-01 can help people with diabetic eye disease (non-proliferative diabetic retinopathy) that is moderate to severe but not yet at the most advanced stage. It may be an option if you have type 1 or type 2 diabetes and have not had certain prior eye treatments.
Santa Barbara, CaliforniaAges 18 years+ - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Los Angeles, CaliforniaAges 12 years+ - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
San Francisco, CaliforniaAges 18–55 - NCT06897475RecruitingPhase 2
Study of LY3457263 for type 2 diabetes on semaglutide or tirzepatide
This study tests if adding LY3457263 helps lower blood sugar in people with type 2 diabetes who are already taking a stable dose of semaglutide or tirzepatide. You will be randomly assigned to get either LY3457263 or a placebo.
Santa Ana, CaliforniaAges 18–75 - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
Duarte, CaliforniaAges 18–55 - NCT06923046Recruiting
Team Clinic for teens with type 2 diabetes
This trial tests a group clinic program for teens with type 2 diabetes. It aims to help you manage your diabetes better with support from others your age and your family.
Los Angeles, CaliforniaAges 12–18 - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Walnut Creek, CaliforniaAges 18–50 - NCT06981234RecruitingPhase 2
Acetazolamide for type 1 diabetes
This trial tests whether a medicine called acetazolamide (used for altitude sickness) can help people with type 1 diabetes. It compares how your body responds while on the drug versus a placebo, using a crossover design so everyone gets both treatments.
La Jolla, CaliforniaAges 18 years+ - NCT06999356Recruiting
Salud Diabetes: Lifestyle Changes and Glucose Monitoring Study
This study tests if combining lifestyle coaching with a continuous glucose monitor (CGM) helps people with type 2 diabetes improve their blood sugar control. You'll track your glucose levels using a study device and see how daily habits affect them.
Santa Barbara, CaliforniaAges 18–89 - NCT07065721Recruiting
Continuous glucose monitors for young adults with type 2 diabetes
This trial tests if using a continuous glucose monitor (a small sensor that checks your sugar levels without fingersticks) helps young adults manage type 2 diabetes better. You will wear the sensor and use a phone app to track your glucose.
San Diego, CaliforniaAges 18–45 - NCT07116876Recruiting
Placental membrane vs standard care for diabetic foot ulcers
This study tests a special wound covering made from donated placental tissue to see if it helps diabetic foot ulcers heal better than usual care. It may be an option for people with diabetes who have a foot sore that hasn't healed after 30 days.
Castro Valley, CaliforniaAges 21–80 - NCT07187531RecruitingPhase 2
Testing a new drug to slow type 1 diabetes progression
This trial tests an experimental drug called SAB-142 to see if it can slow down or stop the progression of type 1 diabetes. It is designed for people who were recently diagnosed and still produce some insulin on their own.
San Francisco, CaliforniaAges 5–40 - NCT07209475RecruitingPhase 4
Amnio-Maxx for healing diabetic foot ulcers
This trial tests whether a special wound dressing called Amnio-Maxx can help heal foot ulcers in people with diabetes. You may qualify if you have a diabetic foot ulcer that hasn't healed much with standard care.
Burbank, CaliforniaAges 18 years+ - NCT07219602RecruitingPhase 3
Study of obicetrapib and ezetimibe for diabetes and metabolic syndrome
This trial tests a combination medication (obicetrapib plus ezetimibe) taken daily to lower cholesterol and triglycerides in people with type 2 diabetes or metabolic syndrome who are already on standard cholesterol treatment. It may help reduce heart risks.
La Jolla, CaliforniaAges 18 years+ - NCT07225218Recruiting
Diabetes prevention program for UCLA students
This study tests a wellness program for UCLA undergraduates who are at risk for developing diabetes. It aims to help students prevent diabetes through support and education.
Los Angeles, CaliforniaAges 17–25 - NCT07260110Recruiting
Study of teplizumab vs. no treatment in stage 2 type 1 diabetes
This study watches people with stage 2 type 1 diabetes who either get teplizumab or not, to compare their real-world experiences. It helps researchers learn how the drug affects daily life.
San Francisco, CaliforniaAges 8 years+ - NCT07296484RecruitingPhase 2
Clofutriben for hard-to-control type 2 diabetes
This trial tests a new medication, clofutriben, for people with hard-to-control type 2 diabetes who might also have mild excess of a stress hormone called cortisol. It aims to see if the drug can help lower blood sugar and improve diabetes management.
Northridge, CaliforniaAges 18 years+ - NCT07341373RecruitingPhase 1
Testing a new insulin delivery method for type 1 diabetes
This study tests a new way to give insulin directly into the abdomen (intraperitoneal) for people with type 1 diabetes. It will check how safe and effective a single dose is over 12 hours, using a special procedure to keep blood sugar stable (clamp).
Chula Vista, CaliforniaAges 18–60 - NCT07355270Recruiting
Radiofrequency vapor ablation for type 2 diabetes
This trial tests a new device that uses radiofrequency energy to treat the lining of the upper small intestine in people with type 2 diabetes. The goal is to see if this treatment is safe and helps improve blood sugar control.
Newport Beach, CaliforniaAges 22–65 - NCT02734277Recruiting
Extending a past Type 1 diabetes immune study
This study is for people who already took part in an earlier immune-tolerance program for Type 1 diabetes. It tests whether continuing follow-up and assessments can be done safely and may help learn more about long-term immune effects of treatment.
San Francisco, CaliforniaAges 8–35 - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Newport Beach, CaliforniaAges 18 years+ - NCT07415954RecruitingPhase 2
Testing a new diabetes medicine for blood sugar control
This study tests a new medicine, NNC0662-0419, in people with type 2 diabetes. You must be willing to lose a lot of weight (more than a quarter of your current weight) as part of the study to see if the medicine helps lower blood sugar.
Lancaster, CaliforniaAges 18–75 - NCT07076199RecruitingPhase 3
Weekly vs daily insulin for type 1 diabetes
This study tests a new once-weekly insulin (icodec) against a standard daily insulin (glargine), both taken with mealtime insulin. It aims to see which works better to control blood sugar in adults with type 1 diabetes.
Concord, CaliforniaAges 18 years+ - NCT07502508RecruitingPhase 2
Icovamenib for type 2 diabetes with Ozempic
This trial tests an investigational pill called icovamenib for people with type 2 diabetes who are already on Ozempic but still have high blood sugar. The goal is to see if adding icovamenib helps lower blood sugar more safely.
Montclair, CaliforniaAges 18–70
Diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting diabetes studies listed above.
- University of California, San Francisco · 5 studies
- Ark Clinical Research · 3 studies
- Diablo Clinical Research · 3 studies
- Scripps Health · 3 studies
- Alliance Clinical · 2 studies
- Hoag Memorial Hospital Presbyterian · 2 studies
- Los Angeles Institute for Metabolic Research · 2 studies
- Pacific Clinical Studies · 2 studies
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in California?
- Yes. We're currently tracking 189 recruiting diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.