Clinical trials · California
Diabetes clinical trials in California
We’re tracking 189 recruiting diabetes studies with a site in California — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Escondido, CaliforniaAges 18 years+ - NCT07546929RecruitingPhase 2
HP-211 Safety Study for Type 2 Diabetes Treatment
This study tests a new medicine called HP-211 in people with early-stage type 2 diabetes to see if it's safe and helps control blood sugar. You'd take the study drug along with your current diabetes management.
Canoga Park, CaliforniaAges 18 years+ - NCT07561541RecruitingPhase 4
Extended Antibiotics for Diabetic Leg Fracture Surgery
This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.
Los Angeles, CaliforniaAges 18 years+ - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Escondido, CaliforniaAges 18 years+ - NCT07588100RecruitingPhase 1
Safety study of RO7663498 eye injection for diabetic retinopathy
This is an early-stage safety study testing a new medicine injected directly into the eye to treat diabetic retinopathy (damage to blood vessels in the retina caused by diabetes). The study checks if the medicine is safe and how the body processes it.
Glendale, CaliforniaAges 18 years+ - NCT07598773Enrolling by invitation
Continuous glucose monitoring study for prediabetes and type 2 diabetes
This study asks you to wear a glucose monitor and smart ring for several months to help researchers understand how blood sugar changes throughout the day in people with prediabetes or type 2 diabetes. The goal is to learn how lifestyle and medications affect blood sugar control.
San Francisco, CaliforniaAges 18 years+ - NCT07019649Enrolling by invitation
AYUDA program for younger Latinx adults with type 2 diabetes
This study tests a program called AYUDA, which sends helpful text messages and support to younger Latinx adults (ages 18–44) who were recently diagnosed with type 2 diabetes and are raising children. The goal is to see if this program helps manage diabetes better.
Pleasanton, CaliforniaAges 18–44 - NCT06002048Enrolling by invitation
AI Study for Diabetes Insights
This study uses artificial intelligence to better understand type 2 diabetes. It is open to adults with or without type 2 diabetes, and aims to improve care for everyone.
San Diego, CaliforniaAges 40–85 - NCT05704309Enrolling by invitation
Study of diabetes prevention participants using brain scans
This study looks at how people who previously took part in a diabetes prevention program are doing over time, including brain health using MRI scans for some participants. It may help researchers understand who is at higher risk for memory and thinking problems and why.
Alhambra, CaliforniaAges Any age - NCT06962839RecruitingPhase 2
Study of BI 1815368 for diabetic macular edema
This trial tests an experimental medication (BI 1815368) given as an eye injection for people with diabetic macular edema, a condition where fluid builds up in the center of the retina and blurs vision. The study aims to see if this new treatment can reduce swelling and improve vision.
Arcadia, CaliforniaAges 18 years+ - NCT07734844RecruitingPhase 3
New vs existing treatment for diabetic macular edema
This study compares a new medication, tabirafusp tedromer, to an existing treatment, aflibercept, for people with diabetic macular edema (swelling in the back of the eye from diabetes). It may help if your DME hasn't improved or you're looking for a new option.
Glendale, CaliforniaAges 18 years+ - NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Huntington Beach, CaliforniaAges 18 years+ - NCT07685808RecruitingPhase 2
Testing a weight loss injection for people with overweight or obesity
This study tests an injectable medication called Olatorepatide to help people with overweight or obesity lose weight. It is only for people without diabetes who meet specific body mass index (BMI) requirements.
Walnut Creek, CaliforniaAges 18 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
San Diego, CaliforniaAges 18 years+ - NCT06616844Recruiting
Patch for non-healing diabetic foot ulcers
This trial tests a special patch made from pig tissue (placenta) placed on diabetic foot ulcers that are not healing well. If you have a foot ulcer that has been present for 4 to 52 weeks and is not shrinking, you may be able to join the study.
Fresno, CaliforniaAges 18 years+ - NCT06010433Recruiting
CERAMENT G treatment tracking study
This study tracks how well the CERAMENT G device works for people getting it as part of their treatment. It helps doctors gather real-world safety and effectiveness information.
San Diego, CaliforniaAges 18 years+ - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Northridge, CaliforniaAges 18 years+ - NCT07284875RecruitingPhase 3
Ribupatide for weight loss in adults without diabetes
This trial tests a new medication, Ribupatide, to see if it helps people with obesity or overweight who also have weight-related health problems. You cannot have diabetes to join.
Escondido, CaliforniaAges 18 years+ - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Escondido, CaliforniaAges 18 years+ - NCT06368817RecruitingPhase 2
Lower radiation dose for children with CNS germinoma
This trial will see if giving a lower dose of radiation therapy can still effectively treat children and young adults with a type of brain tumor called germinoma. The goal is to reduce side effects while keeping the cancer under control.
Loma Linda, CaliforniaAges 3–29 - NCT03752840Recruiting
Community eye-worker program in Nepal
This trial tests a village-based approach to bring eye care closer to older community members. If you live in the right area and are willing to participate, it may help improve access to eye screening and services.
San Francisco, CaliforniaAges 60 years+ - NCT07701590Recruiting
New wound dressings for hard-to-heal leg and foot ulcers
This study tests a special amniotic membrane wound dressing compared to a synthetic wound matrix for stubborn diabetic foot ulcers or venous leg ulcers. It may help if your wound has not been healing well for over a month.
San Diego, CaliforniaAges 18 years+ - NCT06884059RecruitingPhase 1
Time-restricted eating for people with early kidney signs
This study tests whether eating only during a certain window each day helps people with type 2 diabetes and small amounts of protein in their urine (a sign of early kidney stress) improve their health. You'll use a smartphone app to log your meals and follow a daily eating schedule.
La Jolla, CaliforniaAges 18–75 - NCT04199676Recruiting
Testing blood sugar after delivery for gestational diabetes
This study checks your blood sugar shortly after birth (on day 0 or day 1) to see how well glucose testing works for people who had gestational diabetes. The results may help guide follow-up care and reduce the risk of longer-term blood sugar problems.
Long Beach, CaliforniaAges 18 years+
Diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting diabetes studies listed above.
- Diablo Clinical Research · 4 studies
- Desert Oasis Healthcare Medical Group · 2 studies
- Headlands Research - AMCR Institute · 2 studies
- Kailera Clinical Site · 2 studies
- Neighborhood Healthcare · 2 studies
- North Park Podiatry · 2 studies
- Retina Associates of Southern California · 2 studies
- University of California San Diego · 2 studies
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in California?
- Yes. We're currently tracking 189 recruiting diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.