Clinical trials · Massachusetts
Diabetes clinical trials in Massachusetts
We’re tracking 95 recruiting diabetes studies with a site in Massachusetts — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT06931275Recruiting
Reducing technology gaps in type 1 diabetes care
This trial tests if sending reminders to doctors can help more Black and Hispanic people with type 1 diabetes get access to helpful diabetes technology. It aims to reduce unfair differences in who gets to use these tools.
Boston, MassachusettsAges 2–95 - NCT07043426Recruiting
Diabetes care support for social needs
This study tests if connecting people with type 2 diabetes who have high A1C levels (9% or more) to community resources for social needs (like food or housing) can help improve their diabetes control. It aims to see if addressing life challenges outside the clinic helps lower blood sugar.
Boston, MassachusettsAges 18 years+ - NCT07187531RecruitingPhase 2
Testing a new drug to slow type 1 diabetes progression
This trial tests an experimental drug called SAB-142 to see if it can slow down or stop the progression of type 1 diabetes. It is designed for people who were recently diagnosed and still produce some insulin on their own.
Boston, MassachusettsAges 5–40 - NCT07296484RecruitingPhase 2
Clofutriben for hard-to-control type 2 diabetes
This trial tests a new medication, clofutriben, for people with hard-to-control type 2 diabetes who might also have mild excess of a stress hormone called cortisol. It aims to see if the drug can help lower blood sugar and improve diabetes management.
Springfield, MassachusettsAges 18 years+ - NCT02734277Recruiting
Extending a past Type 1 diabetes immune study
This study is for people who already took part in an earlier immune-tolerance program for Type 1 diabetes. It tests whether continuing follow-up and assessments can be done safely and may help learn more about long-term immune effects of treatment.
Boston, MassachusettsAges 8–35 - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Boston, MassachusettsAges 18 years+ - NCT06869057Recruiting
Improving diabetes care after hospital discharge
This study tests a redesigned discharge process to help people with type 2 diabetes manage their health after leaving the hospital. It focuses on patients who also have unmet social needs, like food or housing issues.
Worcester, MassachusettsAges 18 years+ - NCT07415954RecruitingPhase 2
Testing a new diabetes medicine for blood sugar control
This study tests a new medicine, NNC0662-0419, in people with type 2 diabetes. You must be willing to lose a lot of weight (more than a quarter of your current weight) as part of the study to see if the medicine helps lower blood sugar.
Boston, MassachusettsAges 18–75 - NCT07076199RecruitingPhase 3
Weekly vs daily insulin for type 1 diabetes
This study tests a new once-weekly insulin (icodec) against a standard daily insulin (glargine), both taken with mealtime insulin. It aims to see which works better to control blood sugar in adults with type 1 diabetes.
Boston, MassachusettsAges 18 years+ - NCT05911256Enrolling by invitation
Community health coach plus pharmacist to improve diabetes sugars
This study tests whether a team of community health worker and pharmacist can help improve blood sugar control in people with type 2 diabetes. You may be asked to use a continuous glucose monitor (a sensor that tracks sugar levels) and take part in support visits.
Worcester, MassachusettsAges 25–75 - NCT05704309Enrolling by invitation
Study of diabetes prevention participants using brain scans
This study looks at how people who previously took part in a diabetes prevention program are doing over time, including brain health using MRI scans for some participants. It may help researchers understand who is at higher risk for memory and thinking problems and why.
Boston, MassachusettsAges Any age - NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Boston, MassachusettsAges 18 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Boston, MassachusettsAges 18 years+ - NCT06616844Recruiting
Patch for non-healing diabetic foot ulcers
This trial tests a special patch made from pig tissue (placenta) placed on diabetic foot ulcers that are not healing well. If you have a foot ulcer that has been present for 4 to 52 weeks and is not shrinking, you may be able to join the study.
Boston, MassachusettsAges 18 years+ - NCT06575868Recruiting
Can myo-inositol prevent gestational diabetes in pregnancy?
This study tests whether a supplement called myo-inositol (a natural sugar-like substance) can help prevent gestational diabetes in pregnant women with obesity. If you join, you will wear a continuous glucose monitor to track your blood sugar levels and might take the supplement or a placebo.
Boston, MassachusettsAges 18–45 - NCT05862818Recruiting
Food timing study to see if it lowers diabetes risk
This study looks at whether changing when you eat can reduce the chance of developing diabetes. You’d need to be generally healthy and meet specific lifestyle and body-size requirements.
Boston, MassachusettsAges 18–45 - NCT06449677RecruitingPhase 3
Bionic pancreas study for cystic fibrosis related diabetes
This trial tests if an automated insulin delivery system (the iLet bionic pancreas) can safely and effectively manage blood sugar in people with cystic fibrosis related diabetes (CFRD). If you have CFRD and already use insulin, this study may help you learn if a bionic pancreas works well for you.
Boston, MassachusettsAges 14 years+ - NCT05317585Recruiting
Continuous glucose monitor use during early pregnancy with type 2 diabetes
This study tests whether using a continuous glucose monitor during pregnancy is useful for people with type 2 diabetes. It may help track blood sugar levels more closely to support safer pregnancy care.
Worcester, MassachusettsAges 18 years+ - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Quincy, MassachusettsAges 18 years+ - NCT06368817RecruitingPhase 2
Lower radiation dose for children with CNS germinoma
This trial will see if giving a lower dose of radiation therapy can still effectively treat children and young adults with a type of brain tumor called germinoma. The goal is to reduce side effects while keeping the cancer under control.
Boston, MassachusettsAges 3–29 - NCT06988462Recruiting
Bottarga supplement for metabolic health
This study tests a supplement called bottarga, made from fish eggs, to see if it improves cholesterol, blood sugar, or weight in people with metabolic problems like high cholesterol or prediabetes. It is a small pilot study for Massachusetts residents.
Sommerville, MassachusettsAges 18–60 - NCT03549559Recruiting
Heart imaging study in healthy people and specific conditions
This study uses heart imaging to look at changes in the heart muscle. It includes healthy volunteers and people with diabetes or aortic stenosis, to understand differences seen on scans.
Boston, MassachusettsAges 18–85 - NCT03710928Recruiting
Very low carbohydrate diet versus standard diet for type 1 diabetes
This study compares a very low carbohydrate diet to a regular diet to see how well blood sugar control works for adults with type 1 diabetes. It may help you understand which eating pattern is easier and safer for managing daily glucose with modern diabetes technology.
Boston, MassachusettsAges 18–40 - NCT04101669Recruiting
Diabetes device trial to improve blood sugar and weight
This study tests the RESET System to help people with type 2 diabetes lower their average blood sugar (HbA1c) despite current medication. It may also affect weight and safety outcomes by changing how food moves through the gut.
Boston, MassachusettsAges 22–65
Diabetes trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting diabetes studies listed above.
- Boston Medical Center · 4 studies
- Brigham and Women's Hospital · 4 studies
- Joslin Diabetes Center · 4 studies
- Massachusetts General Hospital · 4 studies
- University of Massachusetts Chan Medical School · 2 studies
- Boston Children's Hospital
- Cambridge Health Alliance
- Care Access
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in Massachusetts?
- Yes. We're currently tracking 95 recruiting diabetes studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.