Clinical trials · Pennsylvania
Diabetes clinical trials in Pennsylvania
We’re tracking 98 recruiting diabetes studies with a site in Pennsylvania — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06962839RecruitingPhase 2
Study of BI 1815368 for diabetic macular edema
This trial tests an experimental medication (BI 1815368) given as an eye injection for people with diabetic macular edema, a condition where fluid builds up in the center of the retina and blurs vision. The study aims to see if this new treatment can reduce swelling and improve vision.
Bethlehem, PennsylvaniaAges 18 years+ - NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Monroeville, PennsylvaniaAges 18 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
West Chester, PennsylvaniaAges 18 years+ - NCT06616844Recruiting
Patch for non-healing diabetic foot ulcers
This trial tests a special patch made from pig tissue (placenta) placed on diabetic foot ulcers that are not healing well. If you have a foot ulcer that has been present for 4 to 52 weeks and is not shrinking, you may be able to join the study.
McKeesport, PennsylvaniaAges 18 years+ - NCT05722873Recruiting
Study intermittent fasting and its effects on metabolism
This study looks at how intermittent fasting affects your body's “metabolism” (how you use food and manage blood sugar/fats). It may help researchers understand whether this eating pattern changes metabolic health in people at higher risk for type 2 diabetes.
Pittsburgh, PennsylvaniaAges 21–45 - NCT06449677RecruitingPhase 3
Bionic pancreas study for cystic fibrosis related diabetes
This trial tests if an automated insulin delivery system (the iLet bionic pancreas) can safely and effectively manage blood sugar in people with cystic fibrosis related diabetes (CFRD). If you have CFRD and already use insulin, this study may help you learn if a bionic pancreas works well for you.
Philadelphia, PennsylvaniaAges 14 years+ - NCT05071898RecruitingPhase 1
Studying how genetics affect response to GLP-1 weight-loss drugs
This early-stage study looks at how genetic factors may change how people respond to a GLP-1 medicine (semaglutide). The goal is to learn who may benefit most and why, so future treatments can be better matched.
Lancaster, PennsylvaniaAges 18–89 - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Uniontown, PennsylvaniaAges 18 years+ - NCT06880835Recruiting
Inhaled insulin vs injected insulin for exercise blood sugar drops in type 1 diabetes
This trial tests whether a new inhaled insulin (Technosphere) causes fewer low blood sugar episodes during exercise compared to standard injected insulin in people with type 1 diabetes who use an automated insulin pump. It may help you avoid hypoglycemia while staying active.
Philadelphia, PennsylvaniaAges 18–65 - NCT06368817RecruitingPhase 2
Lower radiation dose for children with CNS germinoma
This trial will see if giving a lower dose of radiation therapy can still effectively treat children and young adults with a type of brain tumor called germinoma. The goal is to reduce side effects while keeping the cancer under control.
Philadelphia, PennsylvaniaAges 3–29 - NCT04661215Recruiting
Testing stomach opening muscle problems in people with gastroparesis
This study looks at whether abnormal function of the pyloric “stomach outlet” muscle is linked to gastroparesis symptoms (slow stomach emptying). It may help researchers better understand what causes symptoms and guide future treatments.
Philadelphia, PennsylvaniaAges 18–85 - NCT04731272RecruitingPhase 2
Weekly GLP-1 medicine for blood sugar issues in adults with CF
This Phase 2 trial tests a weekly GLP-1 medicine (dulaglutide) to improve blood sugar control in adults with cystic fibrosis (CF) who have trouble managing glucose. It may help people with CF-related prediabetes or diabetes by improving how their body handles sugar.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05197920Recruiting
Study of diabetes after acute pancreatitis
This study looks at why some people develop diabetes after acute pancreatitis and how that process works in the body. It may help doctors better predict risk and tailor care for people recovering from pancreatitis.
Pittsburgh, PennsylvaniaAges 18–75 - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Wyomissing, PennsylvaniaAges 18 years+ - NCT06325202Recruiting
A study on preventing low blood sugar with a closed loop system
This trial tests whether a closed-loop insulin pump combined with education can help people with type 1 diabetes better recognize and avoid dangerously low blood sugar. It may be a good fit if you've had diabetes for a long time and have trouble sensing when your blood sugar drops.
Philadelphia, PennsylvaniaAges 18–75 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Camp Hill, PennsylvaniaAges 55 years+ - NCT06401577Recruiting
Acute pancreatitis and diabetes risk study
This study looks at how acute pancreatitis affects blood sugar and the risk of developing diabetes. You'll wear a continuous glucose monitor (CGM) sensor and have metabolic tests to track changes over time.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06605807Recruiting
Improving medication decisions for older adults in the hospital
This study examines how doctors prescribe medications for older adults with chronic conditions during their hospital stay. The goal is to learn how to make safer and more effective prescribing choices for patients aged 65 and older who are discharged home.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06614322RecruitingPhase 2
Testing Pain Sensitivity and Pain Relief for Nerve Pain in Feet
This study looks at how people with long-term nerve pain in their feet respond to pain relief. It aims to match the right treatment to each person based on their pain sensitivity.
Pittsburgh, PennsylvaniaAges 18–80 - NCT06959277Recruiting
Walkasins study for balance with peripheral neuropathy
This trial tests if a wearable device called Walkasins can improve balance and walking in people with peripheral neuropathy. It may help if you have trouble with balance and your foot size fits the device.
Pittsburgh, PennsylvaniaAges 55 years+ - NCT06995651RecruitingPhase 1
Dorzagliatin for blood sugar in cystic fibrosis
This study tests a drug called dorzagliatin to see if it can help control blood sugar in adults with cystic fibrosis who have pancreatic insufficiency and abnormal glucose tolerance.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT00097292Recruiting
Preventing Type 1 Diabetes in At-Risk People
This study looks for people at high risk of developing type 1 diabetes (based on family history or blood markers) and follows them over time to understand disease development. The goal is to eventually prevent or delay type 1 diabetes in people who don't have it yet.
Pittsburgh, PennsylvaniaAges 2–45
Diabetes trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting diabetes studies listed above.
- University of Pittsburgh · 6 studies
- University of Pennsylvania · 4 studies
- Children's Hospital of Philadelphia · 2 studies
- Preferred Primary Care Physicians · 2 studies
- UPMC Children's Hospital of Pittsburgh · 2 studies
- Altoona Center for Clinical Research
- Capital Area Research, LLC
- Clinical Research Center of Reading, LLC
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in Pennsylvania?
- Yes. We're currently tracking 98 recruiting diabetes studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.