Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04450927Enrolling by invitation
Collecting health data from NHLBI patients and donors
This study collects information about standard care for people seen by the NHLBI, and also about donors. It helps researchers understand what happens in real-world care, which can improve future treatment decisions.
Bethesda, MarylandAges 2–120 - NCT04343417Enrolling by invitation
Kidney biopsy study that stores samples for research
This study collects and stores kidney biopsy samples (and related information) to help researchers understand kidney diseases. You may be able to join if you are already scheduled for a kidney biopsy and can consent.
New Haven, ConnecticutAges 18–99 - NCT04234139Enrolling by invitation
Study of severe alcoholic hepatitis patients before early liver transplant
This study follows people with severe alcoholic hepatitis who are being considered for an early liver transplant before they’ve been sober for 6 months. It aims to better understand this group’s situation and ethics/safety as early transplantation plans are made.
Baltimore, MarylandAges 18 years+ - NCT04190758Enrolling by invitation
Early arthritis study for RA, psoriatic arthritis, and psoriasis
This study looks at people with early arthritis related to rheumatoid arthritis, psoriatic arthritis, or psoriasis. Researchers want to understand how these early conditions behave and may help guide better treatment decisions.
GothenburgAges 18–80 - NCT04042532Enrolling by invitation
Theta-burst brain stimulation for younger-onset Alzheimer’s
This trial tests whether a form of brain stimulation (theta-burst stimulation) can improve thinking and memory in people with younger-onset Alzheimer’s. It also compares results with people without dementia who meet similar age and health requirements.
Taoyuan, GuishanAges 50–75 - NCT03901521Enrolling by invitation
Biobank for people with autosomal dominant polycystic kidney disease
This study collects samples and health information from adults with autosomal dominant polycystic kidney disease (ADPKD) who are having their own kidney removed. It helps researchers learn more about ADPKD and its genetic changes to support future treatments.
New York, New YorkAges 18–100 - NCT03862274Enrolling by invitation
Study of development in children with CLN2 due to TPP1 changes
This study looks at how children’s development progresses in CLN2 disease caused by a specific enzyme problem (TPP1). It may help doctors better understand outcomes and guide future care for children with this diagnosis.
Columbus, OhioAges Any age - NCT03692455Enrolling by invitation
Compare two weight-loss surgeries for reflux over 8 years
This study follows people for up to 8 years to see how two different weight-loss surgeries affect ongoing heartburn and acid reflux. You would join only if you were already enrolled in an earlier related study and can complete required follow-up visits and tests.
Passo Fundo, Rio Grande do SulAges 18–78 - NCT03674255Enrolling by invitation
Tests how accurate heart ultrasound is during stress
This study checks how well a heart ultrasound (echocardiography) works when your heart is at rest and under stress. You may benefit by getting closer attention to how the test is done, especially if it’s being used to look for blocked-heart-blood-flow problems.
Ages 18 years+ - NCT03623672Enrolling by invitation
Study for early signs of Parkinson-related brain changes
This study enrolls people with idiopathic REM sleep behavior disorder, a sleep problem that can come before Parkinson’s disease or related conditions. It aims to better understand early (“prodromal”) changes so future treatments can be targeted earlier.
Sun City, ArizonaAges 18 years+ - NCT03582488Enrolling by invitationPhase 4
Tracking brain changes in probable Lewy body dementia
This trial follows people with probable Lewy body dementia over several years to see how the brain changes on MRI and on memory/thinking tests. It may help researchers understand disease progression and improve future care for Lewy body dementia.
Jacksonville, FloridaAges 18 years+ - NCT03395509Enrolling by invitation
Free screening program for diabetes and heart risks
This study looks at how well and how cost-effective a combined health screening is for diabetes and cardiovascular (heart and blood vessel) risks. You may be invited to attend screening around your 67th birthday.
ViborgAges 67–67 - NCT03319446Enrolling by invitation
Sharing anonymous samples for a diagnostic test
This trial collects and stores anonymous samples from consenting adults. It helps researchers evaluate or improve diagnostic testing without using your personal identity.
Salt Lake City, UtahAges 18–99 - NCT03295279Enrolling by invitation
Use of chest CT scans from WTC Health Plan participants
This study creates a research archive of chest CT scan images from people enrolled in the World Trade Center (WTC) Health Plan program at Mount Sinai. It may help doctors and researchers better understand and track chest health over time using existing scan images.
New York, New YorkAges 18 years+ - NCT03162549Enrolling by invitation
Inflammatory bowel disease registry for adults on biologics or JAKs
This study is a real-world registry that collects information about people with Crohn’s disease or ulcerative colitis who take certain medicines (biologics or tofacitinib). It helps researchers better understand how these treatments are used and how people are doing over time.
Waltham, MassachusettsAges 18 years+ - NCT03089827Enrolling by invitation
Tests how a brain imaging tracer spreads in Alzheimer’s risk
This trial uses a radioactive imaging tracer to see how it moves and settles in the brain in people with risk factors for Alzheimer’s disease. It may help researchers understand which people show tracer patterns linked to Alzheimer’s changes.
Winston-Salem, North CarolinaAges 55 years+ - NCT03044847Enrolling by invitation
Long-term study of COPD in adults in China
This study follows people with COPD (chronic lung disease) over many years to better understand the condition. It may help doctors learn what factors predict worsening over time.
Beijing, Beijing MunicipalityAges 40–75 - NCT03021031Enrolling by invitation
Deep brain stimulation for Parkinson’s patients
This trial studies a type of brain stimulation to help reduce symptoms in people with Parkinson’s disease. You may be able to join if you have Parkinson’s and are being considered for this treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT00001467Recruiting
Study of genes in immune disorders
This research looks at how inherited (genetic) changes may affect the immune system in people with immune problems. It may help by improving understanding of these conditions and, in some cases, guiding faster care for a baby after birth.
Bethesda, MarylandAges 1 day–101 years - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Birmingham, AlabamaAges birth–2 weeks - NCT07564882Recruiting
Music and Mobile Apps to Help Babies With Heart Surgery Pain
This study tests whether music and a mobile app can help reduce pain and stress in babies aged 2–12 months who have had heart surgery. Researchers will measure pain levels and vital signs like heart rate and breathing.
AnkaraAges 2 months–1 year - NCT06092281Recruiting
Can questionnaires improve follow-up after ESD?
This trial tests whether sending questionnaires and feedback helps patients keep up with their follow-up appointments after having a precancerous growth removed from the digestive tract (a procedure called ESD). It aims to see if this approach can make a difference in how well patients stick to their recommended check-ups.
Xi'an, ShaanxiAges 18–80 - NCT07059091RecruitingPhase 2
Allergy medicine for COPD with indoor allergies
This study tests if omalizumab, an allergy medicine, can help people with COPD who are allergic to common indoor allergens and have had recent flare-ups. It aims to see if reducing allergic reactions can improve COPD control.
Birmingham, AlabamaAges 40 years+ - NCT06965725Recruiting
Sizing device for heart valve repair surgery
This trial tests a new tool to help surgeons choose the right size ring during mitral valve repair surgery. It may make the repair fit better and improve outcomes.
Glenview, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,583 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.