Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,353 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04163614Recruiting
Testing blood pressure patterns and fluid removal during dialysis
This study looks at how blood pressure changes during hemodialysis and how much fluid is removed, to see what approach works best for controlling blood pressure. It may help dialysis patients whose blood pressure is often high before or after treatment.
Dallas, TexasAges 18 years+ - NCT04206852Recruiting
Balloon treatment for chronic blood-clot lung vessel disease
This trial tests whether a procedure called balloon pulmonary angioplasty is safe and effective for people with chronic thromboembolic disease in the lungs, especially when surgery isn’t an option. If you have CTEPH, it may help improve lung blood flow and symptoms.
BeijingAges 18 years+ - NCT04162171Recruiting
SBRT treatment study for steady heart rhythm VT
This study looks at using SBRT (high-precision radiation) to treat a dangerous, steady heart rhythm called monomorphic VT. It is meant for people who keep having VT even after prior ablation attempts and after trying a class III “rhythm-stabilizing” medicine.
Halifax, Nova ScotiaAges Any age - NCT04181138Recruiting
Study of childhood primary sclerosing cholangitis types
This study follows children and young adults with primary sclerosing cholangitis (PSC) to understand the condition and how it shows up on scans or biopsy. It may help doctors better recognize PSC and choose the best next steps for care.
Los Angeles, CaliforniaAges 2–25 - NCT04240119Enrolling by invitation
Study blood vessel growth markers in certain brain artery narrowing
This study looks at “angiogenic markers,” which are blood measures that may reflect how blood vessels grow, in people with significant narrowing of a brain artery. It aims to better understand these changes and how they relate to cerebrovascular disease.
Ages 18 years+ - NCT04204135Enrolling by invitation
Tracking hip flexor weakness after specific spine surgeries
This trial follows how hip flexor strength changes after two types of lower-back surgeries (ALIF or LLIF). It may help doctors better predict and prevent weakness in the hip and leg after surgery.
Chicago, IllinoisAges Up to 65 years - NCT04216927RecruitingPhase 3
Neonates on heart-lung bypass get NO to prevent kidney injury
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
Cincinnati, OhioAges 1 day–1 month - NCT04240665Enrolling by invitation
Test a digital notebook for memory problems
This study tests a digital “memory notebook” to help people who have early memory concerns keep track and report changes over time. It may be useful if you’re having mild memory issues and can complete surveys with a study partner.
Sacramento, CaliforniaAges 60 years+ - NCT04163198Recruiting
Testing better airway clearance for weak breathing muscles
This study checks a device approach that helps move mucus out of the lungs in people with neuromuscular (nerve/muscle) conditions and weak breathing. It may help reduce mucus buildup and lower respiratory infections, but you must meet specific breathing and stability requirements.
London, LondonAges 18 years+ - NCT04165109Recruiting
Down syndrome study to test memory and thinking changes
This study enrolls adults with Down syndrome to better understand how thinking and memory develop and change over time. It may help by building a “trial-ready” group and by measuring thinking in a careful, consistent way.
Phoenix, ArizonaAges 25–55 - NCT04180059RecruitingPhase 1
Anti-DP treatment after stem cell transplant to prevent relapse
This early-phase trial tests an anti-DP medicine given after an allogeneic (donor) stem cell transplant. It aims to improve outcomes by targeting immune cells linked to certain transplant match types and reducing relapse risk.
NantesAges 18–75 - NCT04216732Recruiting
Study of medullary thyroid cancer progression in a registry
This study follows people with medullary thyroid cancer to better understand how the disease changes over time, including in advanced stages. You may help improve future treatment planning and care for people with medullary thyroid cancer.
San Francisco, CaliforniaAges 18 years+ - NCT04252950Recruiting
Exercise program after blood-flow procedures for leg artery disease
This study tests whether a community-based exercise program helps people recover and improve walking after a procedure to restore blood flow in the leg arteries. It may help if your main problem is leg circulation problems and you’re able to take part in exercise safely.
Minneapolis, MinnesotaAges 40–90 - NCT04246437RecruitingPhase 1
Brain imaging study for autonomic failure with possible Parkinson disease
This Phase 1 study uses a special injected imaging tracer and an MRI scan to look at brain function in people with autonomic failure. It may help researchers understand what’s happening in conditions that can be related to Parkinson disease, multiple system atrophy, or dementia with Lewy bodies.
Nashville, TennesseeAges 18 years+ - NCT04150640RecruitingPhase 2
Chemo drug combination for advanced stomach or esophagus cancer
This Phase 2 trial tests whether a combination of chemo drugs (oxaliplatin and liposomal irinotecan) plus trastuzumab works better for people with advanced stomach or esophagus adenocarcinoma that has specific tumor markers (HER2 and PDL1). It may help shrink tumors and improve control of the cancer in people who have not had prior treatment for advanced disease.
Madison, WisconsinAges 18 years+ - NCT04160507Recruiting
Biobank study collecting samples about kidney health in Black adults
This study builds a research “bank” (biorepository) of blood and other samples from Black adults with different stages of kidney health, including people with kidney disease and people without known kidney disease. It may help researchers better understand kidney risk and causes over time.
Durham, North CarolinaAges 18 years+ - NCT04156893RecruitingPhase 1/Phase 2
RH-matched blood transfusions for sickle cell patients
This study tests whether giving red blood cells matched to your child’s RH (a blood marker) can improve safety and fit for people with sickle cell disease who need regular transfusions. It may help reduce mismatches by using blood units selected to match the child’s blood type more closely.
Philadelphia, PennsylvaniaAges 6 months+ - NCT04203303Recruiting
Study how your gut microbes affect health and disease
This study looks at how the bacteria (microbes) living in and on your body relate to health and disease. It may help researchers understand what changes in these microbes mean for future treatments.
Rochester, MinnesotaAges 18 years+ - NCT04222062RecruitingPhase 2
Compare Gliadel implant versus focused brain radiation
This Phase 2 study compares two ways to treat brain metastases: a Gliadel wafer placed during planned surgery versus focused stereotactic radiosurgery. It aims to see which approach works better and is safer for people with a limited number of brain tumor spots.
Detroit, MichiganAges 18 years+ - NCT04147559Enrolling by invitation
Long-term follow-up for a specific hip replacement stem
This study checks how well a particular hip replacement stem (the PROFEMUR Preserve Classic Femoral Stem) and matching parts keep working over many years. You may be invited if you had that exact hip replacement combination and can return for long-term checkups.
Scottsdale, ArizonaAges 21 years+ - NCT04234048RecruitingPhase 1
ST-001 trial for stubborn T-cell lymphoma that came back
This Phase 1 trial tests ST-001, an experimental treatment, for T-cell lymphomas that have returned or did not respond to prior therapy. It aims to find a safe dose and see whether it can shrink or control the lymphoma.
Scottsdale, ArizonaAges 18 years+ - NCT04241328Recruiting
Cardiac surgery registry for patients who used a Medtronic device
This study tracks patients who had cardiac surgery using a specific Medtronic heart-surgery device. It mainly collects real-world data to help understand outcomes, and you may be included if you give consent and are not in another device/drug study that could affect the results.
ViennaAges Any age - NCT03806283Recruiting
Study how pregnancy blood vessels change in late pregnancy
This study looks at how blood vessels adapt during late pregnancy, especially around the time of a C-section. Your participation may help researchers understand normal pregnancy changes and how they differ in certain complications.
Madison, WisconsinAges 18–40
Hear when a new Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,353 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.