Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,578 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05728697Recruiting
Test a liver ultrasound method to measure fat and stiffness
This trial tests a special ultrasound technique during an endoscopy to see how well it can detect changes in the liver from non-alcoholic fatty liver disease. It may help improve non-invasive assessment before or alongside a follow-up liver biopsy.
Boston, MassachusettsAges 18 years+ - NCT05732727RecruitingPhase 3
Stronger BP lowering using diuretics in kidney disease
This Phase 3 trial compares a plan that uses diuretics (water pills) to lower blood pressure more, versus usual blood pressure care, in people with uncontrolled hypertension and moderate-to-severe chronic kidney disease. It may help your blood pressure control while monitoring safety closely because kidney function changes how medicines work.
AngersAges 18 years+ - NCT05732714Recruiting
Reduce heart event risk after major non-heart surgery
This study looks at ways to lower the chance of heart-related problems after major surgery that is not directly related to the heart. It focuses on people at higher heart risk who are expected to stay in the hospital for at least two days after surgery.
Toronto, OntarioAges 45–75 - NCT05732870Recruiting
Study looks for blood and gene signals that affect bone health
This study collects information and samples around the time of certain bone or joint surgeries (like joint replacement or fracture repair) to learn what factors help or harm bone healing. The results may help find better targets to improve long-term bone health and recovery.
London, Greater LondonAges 18–110 - NCT05733702Recruiting
Study of Crohn’s and ulcerative colitis treatment changes
This study follows adults with Crohn’s disease or ulcerative colitis when their treatment is changed. It collects health information and samples to better understand how treatment changes affect people over time.
LuxembourgAges 18 years+ - NCT05733832Recruiting
Transitional care after hospital discharge for serious liver disease
This trial tests an extra support program after you leave the hospital to help people with advanced liver disease avoid complications and stay on track. It may help by providing structured follow-up soon after discharge.
Chicago, IllinoisAges 18 years+ - NCT05733845Recruiting
Study of why some bowel inflammation treatments don’t work
This study looks at blood and/or tissue “molecular” (cell-level) reasons why treatments don’t fully work in adults with Crohn’s disease or ulcerative colitis. If you are starting a biologic or small-molecule medicine and still have moderate to severe symptoms, you may be able to contribute to research that helps improve future care.
Vandœuvre-lès-Nancy, CHRU de NancyAges 18 years+ - NCT05734378Recruiting
Study aims to predict outcomes in small blood vessel brain disease
This trial is looking at how brain “small blood vessel disease” changes over time and what outcomes to expect. If you have certain symptoms or scan findings from this condition, your care team may compare your prognosis to help guide future treatment planning.
BernAges 16 years+ - NCT05736419RecruitingPhase 2
Immune-suppressing treatment before stem cell transplant for blood disorders
This Phase 2 study tests an immune-suppressing treatment for people with sickle cell disease or beta-thalassemia who are preparing for a stem cell transplant from a donor. It aims to help the transplant work better by changing the immune response.
Basking Ridge, New JerseyAges 2–50 - NCT05738824Recruiting
Study how inflammatory muscle diseases naturally change over time
This study follows people with suspected or confirmed inflammatory muscle disease (and sometimes healthy adults) to better understand how the condition progresses and what changes over time. It may help researchers identify patterns that could guide future treatments.
Bethesda, MarylandAges 2–120 - NCT05741151Recruiting
Testing a nerve target in Parkinson’s disease
This trial is studying the “superior cervical ganglion” as a possible treatment approach for Parkinson’s disease. It may help people whose symptoms are truly caused by Parkinson’s, not by another condition.
RomeAges 30–80 - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT05742776Recruiting
Ultrasound and sleep quality check in carpal tunnel
This trial studies whether ultrasound exam findings match how well you sleep if you have carpal tunnel syndrome. It may help doctors better understand which ultrasound results go along with worse sleep and symptoms.
Afyonkarahisar, Afyonkarahi̇sarAges 20–80 - NCT05746221Recruiting
Study inflammation and brain small-vessel disease in adults 40+
This study looks at inflammation-related changes in people with “small-vessel disease” of the brain. It will follow participants over time to understand the condition better and see how brain symptoms may change.
NijmegenAges 40 years+ - NCT05746715Recruiting
Study of people at risk for inherited CJD before symptoms
This study follows people who have a close family member with inherited Creutzfeldt-Jakob disease (CJD) to understand how the disease develops before any symptoms. It may involve genetic testing and safety-required procedures like brain scans and a spinal fluid test to learn about early changes.
Tel AvivAges 50 years+ - NCT05748028Recruiting
Testing treatment for pain and nerve symptoms in Parkinson’s
This study looks at pain and “autonomic” (automatic body) symptoms in people with Parkinson’s disease or a related condition called multiple system atrophy. It aims to understand what helps and to learn more about these symptoms in different types of Parkinson-like illnesses.
Telese Terme, BeneventoAges 18 years+ - NCT05748717Recruiting
Tests blood flow in children with sickle cell
This study measures how well blood flows through brain arteries in children with sickle cell disease using a noninvasive ultrasound test. It may help doctors better understand stroke risk and how treatments like hydroxyurea or recent care affect blood flow.
Kingston, Saint Andrew ParishAges 4–16 - NCT05752656Recruiting
Tracking outcomes after deep brain stimulation for Parkinson’s
This study follows people with Parkinson’s disease to see how their thinking, behavior, and movement change over time after deep brain stimulation. It may help doctors better understand what to expect from this treatment.
RomeAges 18 years+ - NCT05757141RecruitingPhase 1/Phase 2
Study of fosigotifator for vanishing white matter disease
This early-phase study tests fosigotifator in people with vanishing white matter disease (VWM). The goal is to see whether the treatment is safe and could affect how the disease works in the body and brain.
Boston, MassachusettsAges 6 months+ - NCT05759468RecruitingPhase 2
Add NAD to help protect kidneys in diabetes
This Phase 2 study tests whether adding NAD can improve kidney health in people with diabetes-related kidney disease. It is designed for people with certain urine lab results showing kidney stress, while keeping blood sugar and safety limits within range.
Boston, MassachusettsAges 30 years+ - NCT05759780Recruiting
Check how an eye probe measures tissue softness
This study uses a special eye/skin/gum imaging test to measure how tissues behave. It may help researchers improve noninvasive ways to understand eye and tissue health, and in some parts of the study, mild keratoconus.
Boston, MassachusettsAges 18–75 - NCT05761275Recruiting
Sexual quality of life after minimally invasive benign surgery
This study looks at how minimally invasive “vNOTES” surgery affects women’s sexual quality of life after a non-cancer (benign) gynecologic procedure. You might be eligible if you recently had this type of surgery and meet specific health, infection, and language requirements.
GenevaAges 18–70 - NCT05765110Recruiting
Tracking speech, movement, and thinking in Parkinson’s disease
This study looks at how people with Parkinson’s disease speak, move, and think to see whether these patterns can act like a “biomarker” (a measurable sign) of the disease. It also involves healthy volunteers to compare results.
PragueAges 30–75 - NCT05765370Recruiting
LDL cholesterol study in people 75+ with heart or blood vessel disease
This trial studies how to lower “bad” cholesterol (LDL) in people age 75 and older who have already had heart, brain, or leg/blood-vessel problems from blocked arteries. The goal is to see if the approach helps prevent further cardiovascular events (like heart attack or stroke).
Beijing, Beijing MunicipalityAges 75 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,578 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.