Clinical trials · Boston, MA
Down Syndrome clinical trials in Boston
We’re tracking 166 recruiting down syndrome studies with a site in or near Boston — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT02399527Recruiting
Lymphatic problem registry for tracking outcomes
This study enrolls people with certain lymphatic (lymph fluid) conditions to collect information and track how they do over time. It may help doctors better understand outcomes and improve care.
Boston, MassachusettsAges Any age - NCT00315380Recruiting
Study following people with eosinophilic granulomatosis with polyangiitis
This study looks at the health course of people who have eosinophilic granulomatosis with polyangiitis, a rare inflammatory condition. Your participation may help researchers better understand how the illness changes over time.
Boston, MassachusettsAges Any age - NCT01186913Enrolling by invitation
Natural history study for severe combined immune deficiency (SCID)
This study follows children and adults with SCID and related immune disorders to understand how the illness behaves over time. It also helps researchers learn which testing results and genetic types of SCID match different treatment plans.
Boston, MassachusettsAges Any age - NCT06056908Recruiting
Shwachman Diamond Syndrome Registry and Study
This study is creating a registry for people with Shwachman-Diamond Syndrome (SDS) or similar conditions, and their family members. It aims to learn more about the condition and improve care by collecting health information over time.
Boston, MassachusettsAges Any age - NCT00912041Recruiting
Test of a brain-to-computer device for quadriplegia
This study tests whether a tiny brain computer interface can help people with quadriplegia (loss of movement in all four limbs) communicate or control technology. It’s mainly a feasibility study, meaning the goal is to see if the device can work safely and reliably in real life.
Boston, MassachusettsAges 18–80 - NCT00358943Recruiting
Gaucher disease registry and pregnancy tracking study
This study creates a large, long-term record of people with Gaucher disease and details about pregnancy outcomes. It helps researchers better understand Gaucher over a person’s life and during pregnancy.
Boston, MassachusettsAges Any age - NCT06056635Recruiting
Study of special telescopes for fetal surgery
This study tests two types of small cameras (fetoscopes) to see how well they work for surgery on a baby before birth. Doctors want to learn if these tools can safely perform fetal procedures.
Boston, MassachusettsAges 18–45 - NCT05767658Recruiting
Online messages to support safer infant care
This study tests whether online social network posts and text messages can help pregnant people practice safer infant care after birth. It may help you feel more prepared about feeding and safe sleep.
Boston, MassachusettsAges Any age - NCT02000089RecruitingPhase 3
Pancreas screening study for people at high cancer risk
This Phase 3 study tests a structured plan for checking the pancreas early in people with a higher-than-usual risk of pancreatic cancer. The goal is to find changes sooner, when treatment may be easier.
Boston, MassachusettsAges 18 years+ - NCT06059391RecruitingPhase 2
Vaccine for stem cell donors to prevent CMV
This trial tests whether giving a CMV vaccine to stem cell donors can help protect recipients from CMV infection after transplant. It is for adults with specific blood cancers who are CMV-positive and have a matched related donor.
Boston, MassachusettsAges 18–75 - NCT02074839RecruitingPhase 1
Oral AG-120 for advanced blood cancers with an IDH1 mutation
This Phase 1 study tests an oral medicine called AG-120 in adults with advanced blood cancers that have a specific IDH1 mutation. It also looks at safety and how the treatment works, with frequent blood, urine, and bone marrow samples.
Boston, MassachusettsAges 18 years+ - NCT06078553Recruiting
Natural history study of congenital myasthenic syndromes (CMS)
This study follows people with congenital myasthenic syndrome (CMS) caused by changes in certain genes (DOK7, MUSK, AGRN, or LRP4) over time. It does not test any new drug, but helps researchers understand how the condition changes and how to plan future treatments.
Boston, MassachusettsAges 2 years+ - NCT06247787RecruitingPhase 1
Imetelstat plus chemo for relapsed leukemia in kids
This trial tests a new drug called imetelstat combined with two chemotherapy drugs (fludarabine and cytarabine) for children and teens with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or juvenile myelomonocytic leukemia (JMML) that has come back or not responded to treatment. The goal is to find the safest dose of imetelstat and see if it helps control the cancer.
Boston, MassachusettsAges 1–18 - NCT05129605Recruiting
Prostate cancer genetic risk screening study for men
This study looks at your personal and family risk for prostate cancer and helps decide who should have extra screening like MRI. It may help you find cancer earlier if you are at higher genetic risk.
Boston, MassachusettsAges 35–74 - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Boston, MassachusettsAges Up to 1.3 years - NCT06840496RecruitingPhase 3
Study of oral NA-921 vs placebo for girls and women with Rett syndrome
This trial tests an oral medication called NA-921 in females with Rett syndrome to see if it works better than a placebo. It may be an option for those who have a confirmed MECP2 gene mutation and stable seizure patterns.
Boston, MassachusettsAges 5–20 - NCT02780297Recruiting
Study of rare stone-causing kidney conditions
This study is for people with certain rare kidney conditions that can cause kidney stones. It aims to learn how these conditions behave over time and may help improve future care.
Boston, MassachusettsAges Any age - NCT06782373RecruitingPhase 2
Pacritinib for VEXAS syndrome
This trial tests whether the drug pacritinib can safely reduce inflammation and improve symptoms in people with VEXAS syndrome, a rare genetic condition that causes inflammation in various parts of the body. It may be a new treatment option for those who still have inflammation despite taking steroids.
Boston, MassachusettsAges 18 years+ - NCT00499317Recruiting
Genetic study of chronic pelvic pain and bladder symptoms
This study looks for genetic (inherited) factors behind chronic pelvic pain and related urinary and sexual symptoms. You may be able to help researchers by providing a few samples and answering short questions, which could improve understanding of these conditions.
Boston, MassachusettsAges Any age - NCT04196595Recruiting
Apple study for women’s health using an iPhone app
This study looks at women’s health by collecting information through an Apple Research app on your iPhone. You may help improve how health data is gathered, while also checking in with the study team by agreeing to participate.
Boston, MassachusettsAges 18 years+ - NCT06716411Recruiting
Acupuncture for Gulf War Illness relief
This study tests whether acupuncture can help relieve Gulf War Illness symptoms like fatigue, mood or thinking problems, and muscle or joint pain. You may be able to join if you were deployed to the Gulf region and have had these symptoms for more than 6 months.
Boston, MassachusettsAges 18 years+ - NCT06188689Recruiting
Testing a new diagnostic test for heart rhythm disorders
This study is evaluating a new diagnostic test for Calcium Release Deficiency Syndrome (CRDS) and related heart rhythm disorders. It aims to find out if this test can accurately identify patients with these conditions, which could lead to better diagnosis and treatment.
Boston, MassachusettsAges Any age - NCT04775706RecruitingPhase 2
Test of sonefpeglutide for people with short bowel syndrome
This Phase 2 study tests whether sonefpeglutide is safe and how the body handles it (pharmacokinetics) in people with short bowel syndrome. It may help people who still need nutrition through a tube because their intestinal condition is stable.
Boston, MassachusettsAges 18 years+ - NCT07095998Recruiting
Nerve health in people receiving cisplatin chemotherapy
This study looks at how cisplatin affects nerve activity in the arms and legs. It is for people about to start cisplatin, or those who have had nerve symptoms for at least 3 months after finishing cisplatin.
Boston, MassachusettsAges 18 years+
Hear when a new Down Syndrome trial opens near Boston, MA
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Down Syndrome trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting down syndrome studies listed above.
- Boston Children's Hospital · 6 studies
- Dana-Farber Cancer Institute · 5 studies
- Massachusetts General Hospital · 3 studies
- Beth Israel Deaconess Medical Center · 2 studies
- Brigham and Women's Hospital · 2 studies
- Biomed Testing Facility #BIO-10-02115
- Boston Children's Hospital (BCH)
- Boston University Medical Campus
What taking part in a down syndrome study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting down syndrome studies in Massachusetts.
Common questions
- Are there down syndrome clinical trials near Boston?
- Yes. We're currently tracking 166 recruiting down syndrome studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a down syndrome study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New down syndrome studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.