Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,195 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07086612Recruiting
Sleep apnea and dental crossbite in children
This study looks at the link between sleep apnea (pauses in breathing during sleep) and a narrow upper jaw (crossbite) in children ages 6 to 16. It may help understand if treating the jaw can improve sleep breathing.
RouenAges 6–16 - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT07087912RecruitingPhase 4
Dengue vaccine safety in people with autoimmune rheumatic diseases
This study tests the safety and immune response of a dengue vaccine in people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are on low-dose or no immune-suppressing medications. It also includes healthy volunteers for comparison.
São Paulo, São PauloAges 12–59 - NCT07090551Recruiting
Mouthguard for jaw and neck muscle pain from grinding
This study tests whether a custom mouthguard (occlusal splint) can reduce pain and tension in the jaw and neck muscles. It is for people with bruxism (teeth grinding) and myofascial pain, a type of muscle pain in the jaw area.
IstanbulAges 18–50 - NCT07094035Recruiting
Green tea and probiotics for constipation-predominant IBS
This study tests whether a supplement containing green tea extract and probiotics can improve bowel function in people with irritable bowel syndrome (IBS) that mainly causes constipation. If you have chronic constipation and abdominal pain, this could help.
NaplesAges 18–70 - NCT07095426Recruiting
Fiber supplement study for gut and blood vessel health
This study tests whether taking a fiber supplement can improve gut health and blood vessel health in people with obesity. It may help you understand how your body responds to extra fiber.
Muncie, IndianaAges 18–55 - NCT07095998Recruiting
Nerve health in people receiving cisplatin chemotherapy
This study looks at how cisplatin affects nerve activity in the arms and legs. It is for people about to start cisplatin, or those who have had nerve symptoms for at least 3 months after finishing cisplatin.
Boston, MassachusettsAges 18 years+ - NCT07096297RecruitingPhase 2
Testing two drugs for lower-risk MDS
This trial is testing whether a combination of two drugs, luspatercept and darbepoetin alfa, can help people with lower-risk myelodysplastic syndromes (MDS) who need frequent red blood cell transfusions. The goal is to see if the combination reduces their need for transfusions.
New Haven, ConnecticutAges 18 years+ - NCT07096973Recruiting
Heart rehab recovery study in Davos
This study looks at how people recover during heart rehabilitation at a clinic in Davos. By tracking your progress, researchers hope to learn what helps people get better.
Davos, Kanton GraubündenAges 18 years+ - NCT07098910Recruiting
Surfactant therapy for premature babies with breathing problems
This trial tests whether giving surfactant (a substance that helps lungs stay open) to premature babies with Respiratory Distress Syndrome (RDS) through a mask on the throat (supraglottic airway) is safe and effective. It may be an option for babies who need extra oxygen but are not on a breathing tube.
HanoiAges Up to 2 days - NCT07101523Recruiting
Using technology to promote healthy lifestyles
This trial uses technology to help adolescents with intellectual disabilities adopt healthier habits like exercise and good nutrition. It aims to find out if using smartphones can make it easier to stay active and eat well.
Seville, SpainAges 4–30 - NCT07102797Recruiting
ActiveGirls: Activity, hormones, and diabetes risk in young girls
This study looks at how physical activity and hormone health affect diabetes risk in young girls. It is for girls ages 8 to 12 who are at risk for PCOS (a hormone condition) and insulin resistance, and who have not yet started their period.
Somerville, MassachusettsAges 8 years+ - NCT07104721RecruitingPhase 1
YTS109 cell therapy for severe autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with severe autoimmune diseases that have not responded to standard treatments. The goal is to see if it can reset the immune system and reduce disease activity in conditions like lupus, Sjögren's syndrome, and others.
Hefei, AnhuiAges 18–65 - NCT07105943Recruiting
Exercise intensity study for heart attack recovery
This trial is testing different ways of doing exercise during cardiac rehab to see which helps people feel better and stay active. It's for people who have had a heart attack or similar event in the last year and are considered low risk.
LeiriaAges 18 years+ - NCT07106671RecruitingPhase 2
Siltuximab for side effects after CAR-T in multiple myeloma
This trial tests if the drug Siltuximab can help control side effects (CRS and ICANS) that sometimes happen after CAR-T treatment for multiple myeloma. It may help patients who develop these symptoms.
TianjinAges 18 years+ - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT07107971Recruiting
Drug balloon vs. standard care for fatty heart plaques
This study compares a drug-coated balloon (which releases medicine into the artery) with standard medicines alone for treating fatty plaques in the heart arteries. It is for people who have already had a heart attack and a successful opening of a blocked artery.
AmsterdamAges 18 years+ - NCT07110493Recruiting
Visual snow and TMS study
This study uses a technique called Transcranial Magnetic Stimulation (TMS), which uses magnetic pulses to gently stimulate parts of your brain, to explore how people with visual snow syndrome, color blindness, or normal vision perceive light patterns. This may help understand why visual snow happens and how to treat it.
MoscowAges 18–65 - NCT07111208Recruiting
Air, noise, and lifestyle effects on heart health
This study tests if wearing a wristband that tracks air and noise can help reduce heart risks in people with early signs of metabolic syndrome. You will also get lifestyle tips to help protect your heart.
Kaunas, Kaunas CountyAges 45–64 - NCT07112820Recruiting
Heart imaging test for chest pain without ST elevation
This trial tests if a heart imaging scan (myocardial perfusion) can help doctors better diagnose heart attacks or other conditions in people who come to the hospital with chest pain but without ST elevation on their ECG. It aims to see if the scan adds valuable information before heart catheterization.
Paris, Ilede FranceAges 18 years+ - NCT07117032RecruitingPhase 1
Radiation therapy for cancer-related stomach pain
This trial tests a type of radiation therapy (SBRT) to treat severe stomach pain caused by cancer pressing on nerves near the stomach. It aims to provide pain relief without the need for a standard nerve block procedure.
Cleveland, OhioAges 18 years+ - NCT07118241RecruitingPhase 2
Testing a new eye drop for Sjögren's dry eye
This trial tests a new eye drop made from a natural protein (rhPRG4) to see if it safely and effectively relieves dry eye symptoms in people with Sjögren's syndrome. You'll be randomly assigned to receive the study drop or a placebo (inactive) drop for several weeks.
Sydney, New South WalesAges 18–80 - NCT07118683Recruiting
Brazilian health study for people with HIV or AIDS
This study is creating a record of chronic health conditions (like heart disease, diabetes, or high blood pressure) in people living with HIV or AIDS in Brazil. Joining helps researchers better understand and care for the health needs of people like you.
Goiânia, GoiásAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,195 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.