Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07452263Recruiting
Frailty screening tool for older adults before major surgery
This study tests a simple frailty screening tool in older adults before major surgery. It aims to see if the tool helps identify patients who might need extra support before and after their operation.
Reykjavik, HofudborgarsvaedidAges 70 years+ - NCT07456020Recruiting
Measuring awareness after brain injury in the ICU
This study checks how awake and aware you are using two standard checklists (CRS-R and SECONDs). It's for people with recent brain injuries in intensive care who are still very dependent.
Hessisch Oldendorf, Lower SaxonyAges 18 years+ - NCT07459790RecruitingPhase 2/Phase 3
A new treatment for interstitial cystitis with Hunner's lesions
This study tests a new treatment for women with interstitial cystitis (also called painful bladder syndrome) who have Hunner's lesions (specific sores in the bladder lining). The goal is to see if the new treatment can reduce pelvic pain, frequent urination, and other symptoms.
MoscowAges 18–65 - NCT07460037Recruiting
Brain signal study for speech recovery after stroke or injury
This trial uses a special brain-mapping test called high-density ECoG to study how people who have lost speech due to stroke, brain tumor, or ALS can be helped by reading brain signals when they imagine speaking. It may lead to new devices that let people with severe speech problems communicate using only their thoughts.
Hangzhou, ZhejiangAges 20–80 - NCT07460856Recruiting
Can Cranberries Improve Your Gut and Metabolic Health?
This study tests if eating cranberries can improve your gut health and metabolism. It’s for people who are overweight and have early signs of metabolic problems, like high blood sugar or high triglycerides.
Québec, QuebecAges 25–70 - NCT07463729Recruiting
Back pain study using biofeedback training
This trial tests a stabilization training program using biofeedback (a device that shows you how your muscles are working) to treat chronic low back pain. It may help you strengthen the muscles supporting your spine and reduce your pain.
Tarnów, MałopolskaAges 30–65 - NCT07464093Recruiting
Pilates for joint hypermobility pain
This trial tests if a special Pilates program can reduce pain in people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder. You must have had pain for at least 3 months and be able to get on and off the floor on your own.
Chestnut Hill, MassachusettsAges 18 years+ - NCT07464106Recruiting
Tricuspid valve treatment study for older adults
This study tests if a less invasive tricuspid valve repair or replacement can protect kidney function and improve physical activity in older adults with severe tricuspid valve leakage.
StuttgartAges 18 years+ - NCT07466446Recruiting
Tracking movement after ICU to support recovery
This study uses a small device (accelerometer) to track your movement after leaving the ICU. It aims to see if monitoring physical activity can help improve recovery for patients at higher risk of setbacks.
EdinburghAges 18 years+ - NCT07468461Recruiting
Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome study
This study looks at children with CACP syndrome, a rare genetic condition, to learn more about how the condition affects the body over time.
BariAges Up to 18 years - NCT07472842Recruiting
Study on outcomes for endometriosis in emergency care
This study follows women who come to a specific hospital's emergency department with known endometriosis or symptoms that might be endometriosis, to learn more about their health outcomes over time.
CréteilAges 18 years+ - NCT07473804Recruiting
Salt loss in newborns: beyond common adrenal issues
This study looks at babies who lose too much salt (hyponatremia) due to hormone problems in the first two months of life. It aims to learn more about conditions other than the common one (21-hydroxylase deficiency).
BolognaAges 1–35 - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT07485361Recruiting
Brain scanning in disorders of consciousness
This trial uses a portable brain scanner (fNIRS) to study brain activity in people with disorders of consciousness, like coma or minimally conscious states. It may help doctors better understand and track recovery in these patients. Healthy volunteers are also needed as a comparison group.
Los Angeles, CaliforniaAges 18 years+ - NCT07347418RecruitingPhase 1
CD64 CAR T cell therapy for relapsed or refractory AML
This trial tests a type of immunotherapy called CAR T cells that target a protein called CD64 on leukemia cells. It is for adults with AML that has come back or not responded to treatment, including venetoclax.
Aurora, ColoradoAges 18 years+ - NCT07619885RecruitingPhase 1
Testing a New Blood Thinner Called CG-0255 in Healthy People
This study tests how a new blood-thinning medication (CG-0255) works in the body and compares it with Plavix, a common blood thinner. Researchers will measure how much of the drug enters your bloodstream and what effects it has on your blood clotting ability.
Miami, FloridaAges 18–55 - NCT07493538RecruitingPhase 2
Blood stem cell transplant with lower-intensity chemo for blood cancers
This trial tests a stem cell transplant using milder chemotherapy (treosulfan and fludarabine) followed by a drug called cyclophosphamide to prevent graft-versus-host disease. It aims to make transplant safer for people with blood diseases who cannot handle standard high-dose chemotherapy.
Minneapolis, MinnesotaAges 2–75 - NCT07493629Recruiting
Study on immune status and disease control in inflammatory airway diseases
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Ningbo, ZhejiangAges 18 years+ - NCT07494864Recruiting
Urinary tract health and microbiome study
This study looks at how bacteria and the immune system affect the lower urinary tract. It includes healthy volunteers and people with various urinary conditions, like infections or bladder pain.
Zurich, Canton of ZurichAges 18 years+ - NCT07494968Recruiting
Finding ways to track diet compliance in IBS patients
This study looks for signs in your body—like breath and blood tests—that can show how well you are following a special diet for IBS. It aims to find better ways to track diet compliance, which could help make dietary treatments more effective.
Ann Arbor, MichiganAges 18–65 - NCT07500753Recruiting
Study of a conditioning regimen for older adults with hard-to-treat leukemia or MDS
This trial tests a chemotherapy combination (Clad-LABU) to prepare older patients for a stem cell transplant. It is for people aged 50 or older with relapsed or refractory AML or high-risk MDS.
Suzhou, JiangsuAges 50 years+ - NCT07504731Recruiting
Effect of body position and breathing support on lung function
This study tests how changing a patient's body tilt and adjusting a ventilator's settings can help open up collapsed parts of the lungs. It may help patients with severe lung failure.
Nanjing, JiangsuAges 18 years+ - NCT07507201RecruitingEarly Phase 1
Car-T cells for autoimmune diseases like lupus
This trial tests whether specially-engineered immune cells (CAR-T cells) can help people with certain autoimmune diseases that haven't gotten better with standard treatments. The cells are designed to target and remove faulty B cells that are causing the immune system to attack the body.
Hangzhou, ZhejiangAges 3 years+ - NCT07509021Recruiting
Shoulder impingement, pain thoughts, and treatment sticking
This study looks at how pain, thinking patterns, and sticking to treatment relate in people with shoulder impingement. It aims to help improve physical therapy programs by understanding these factors.
BoluAges 18–65
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,177 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.