Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,182 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07403201RecruitingEarly Phase 1
Combination therapy for PCOS
This trial is testing a combination treatment for PCOS. It is looking for married women who are willing to join the study.
Yogyakarta, DIYAges Up to 45 years - NCT07409337Recruiting
Self-acupressure for period pain and PMS
This trial tests if doing acupressure on yourself can reduce period pain and premenstrual symptoms over about six months. It might help if you have painful periods and are looking for a non-medicine option.
Niğde, MerkezAges 18–30 - NCT07411716Recruiting
Children's liver disease registry in Canada
This study creates a registry to track children with specific genetic liver conditions that cause cholestasis (slow bile flow). Being in the registry helps researchers better understand these diseases and may help future patients.
Calgary, AlbertaAges Up to 18 years - NCT07412860Recruiting
Eye drop test for moderate to severe dry eye
This trial tests a new eye drop (FBV_01) compared to a standard hyaluronic acid eye drop for people with moderate to severe dry eye. The goal is to see if the new drop provides better relief.
Cagliari, CAAges 18 years+ - NCT07413341RecruitingPhase 1
Study of new drug TI-0032-III for hard-to-treat autoimmune diseases
This early-phase trial tests a new drug called TI-0032-III for people with several autoimmune diseases that haven't gotten better with standard treatments. It aims to see if the drug can safely reduce disease activity and offer a new option for people who have few choices left.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07414056Recruiting
Can blood tests predict lung injury in burned children?
This study is testing whether simple blood tests can predict a dangerous lung condition called ARDS in children with severe burns. Researchers will check the child's white blood cell and platelet counts to look for early warning signs that could help doctors treat them faster.
CairoAges 1–12 - NCT07415720Recruiting
Artichoke and Mediterranean diet to prevent type 2 diabetes
This study tests whether a special extract from artichoke by-products, combined with a Mediterranean diet, can help prevent type 2 diabetes in people who are at risk. It aims to improve how your body handles sugar and insulin.
Pamplona, NavarreAges 18–75 - NCT07416201Recruiting
Study of Immune System Aging in Down Syndrome
This study is looking at how the immune system changes over time in people with Down syndrome, and how it may be affected by removal of the thymus gland. The goal is to understand why people with Down syndrome may age faster or have different immune health.
Bethesda, MarylandAges 1–120 - NCT07416968RecruitingPhase 4
Low dose tadalafil vs solifenacin for overactive bladder in women
This study compares two medications—tadalafil (a daily pill for blood flow) and solifenacin (a pill that relaxes the bladder)—to see which works better for women with overactive bladder (OAB), which causes sudden, strong urges to urinate. It will help doctors find a treatment that may have fewer side effects.
Shibīn al Kawm, Al-MinūfiyyahAges 18–75 - NCT07420322Recruiting
Testing brain stimulation for depression and related symptoms
This trial studies a non-invasive brain stimulation treatment for people with depression or related symptoms that haven't improved with standard treatments. The goal is to see how well it works in real-world settings.
MünchenAges 18 years+ - NCT07426172Recruiting
Lactate levels and metabolism in active adults
This trial looks at how high lactate levels (a natural chemical in your body) affect the way your body uses fat and sugar. It is for people with metabolic syndrome who are already physically active.
San Javier, MurciaAges 18–65 - NCT07426146Recruiting
Diet for PCOS: Low glycemic, high fiber study in Yunnan
This study tests if a diet low in quickly digested carbs (low glycemic index) and high in fiber can help women with PCOS who are overweight. You'll follow this eating plan and not change your exercise, to see how it affects your PCOS symptoms over several months.
Gengma County, YunnanAges 19–40 - NCT07426991Recruiting
Multiple sclerosis, thinking, sleep, and tiredness study
This study looks at how multiple sclerosis (MS) affects your thinking, sleep, and tiredness. It compares people with MS who have at least mild fatigue to people without MS who also have sleep problems, to understand these issues better.
DüsseldorfAges 18–79 - NCT07428811Recruiting
Mirror therapy for post-stroke shoulder and hand problems
This trial tests whether task-based mirror therapy can help improve shoulder and hand function in people who have had a stroke less than 6 months ago. It focuses on those with moderate to severe stroke symptoms but without severe muscle stiffness or cognitive issues.
Lahore, Punjab ProvinceAges 45–75 - NCT07428837Recruiting
Brain and body exercises vs. Pilates for balance in Down syndrome
This study compares two types of exercise programs to see which one helps kids with Down syndrome improve their balance and stability. One program combines thinking and movement tasks, while the other uses Pilates exercises.
IslamabadAges 8–13 - NCT07429227Recruiting
Gut health and heart disease: a probiotic study
This trial tests whether natural extracts and probiotics can improve gut health in people who have had a recent heart attack (Acute Coronary Syndrome). It uses special exams to measure changes in gut bacteria.
Peschiera del Garda, VeronaAges 30–70 - NCT07431593Recruiting
Study on inflammation markers in obesity
This trial examines how two blood markers, SII and SIRI, relate to health issues linked to obesity. It aims to help doctors better predict and manage conditions like metabolic problems in overweight and obese adults.
VaraždinAges 18 years+ - NCT07433634Recruiting
Tracking recovery after BVN ablation for chronic low back pain
This study looks at how well a procedure called BVN ablation (which uses heat to stop pain signals from the vertebrae) works for people with chronic low back pain that comes from the spine. If you already have this procedure scheduled, researchers will track your recovery and pain relief over time.
Guilford, ConnecticutAges 18 years+ - NCT07436312Recruiting
Effect of ultra-processed foods on cancer risk in high-risk people
This trial looks at whether eating less ultra-processed foods can lower cancer risk in people who are already at high risk for cancer. It is part of a larger program called Interception that helps monitor and reduce cancer risk.
AvignonAges 18 years+ - NCT07436429Recruiting
Drug-coated balloon for heart attack treatment
This trial tests if a special balloon that releases medication can be used instead of a stent during emergency angioplasty for certain heart attacks. It may help patients who are having a first-time heart attack and are stable enough for the procedure.
ViennaAges 18 years+ - NCT07437391Recruiting
L-carnitine for preterm babies with breathing problems
This trial tests whether giving L-carnitine, a nutrient that helps cells make energy, to premature newborns with respiratory distress syndrome (RDS) can improve their health. It may help their bodies cope better in the NICU.
Muzaffargarh, Punjab ProvinceAges 1 hour–1 day - NCT07439848RecruitingPhase 1/Phase 2
Stem cells for severe lung injury from sepsis
This trial tests if adding stem cells or their growth liquid to standard sepsis treatment helps adults with severe breathing problems. It may improve recovery for those whose family agrees to the study.
Jakarta Pusat, DKI JakartaAges 40 years+ - NCT07441525RecruitingEarly Phase 1
CAR-T cell therapy for hard-to-treat autoimmune blood diseases
This early-stage trial tests a new type of immune cell therapy (CAR-T) that targets two proteins, CD19 and BCMA, in people with autoimmune blood diseases like ITP, AIHA, or Evans syndrome that have not responded to standard treatments. It aims to reset the immune system and reduce production of harmful antibodies.
Wuhan, HubeiAges 18–75 - NCT07444723RecruitingPhase 2/Phase 3
New imaging to find parathyroid tumors before surgery
This study tests two advanced imaging techniques (PET/MR and PET/CT) to find overactive parathyroid glands or tumors that need surgery. Participants get a special scan before surgery to help surgeons locate the problem more accurately.
Bethesda, MarylandAges 18–100
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,182 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.