Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06330350Recruiting
Talking about family planning for genetic skin conditions
This study interviews people with inherited skin conditions (genodermatoses) who want to have children, and the doctors who care for them. The goal is to learn how to better support family planning decisions, like counseling about genetics and pregnancy risks.
Maastricht, LimburgAges Any age - NCT06333041RecruitingPhase 2/Phase 3
CBD study for Sanfilippo syndrome
This study tests whether a cannabis-derived medicine called cannabidiol (CBD) can help children with Sanfilippo syndrome, a rare genetic disorder. It may be a good fit for children who have already tried other treatments or whose disease is more advanced.
Torrance, CaliforniaAges 4 years+ - NCT06334692Recruiting
Autoantibody study in nephrotic syndrome
This study looks for specific proteins (autoantibodies) in your blood that may be linked to certain kidney diseases. It aims to better understand the immune system's role in minimal change disease and FSGS, which could lead to better treatments.
Ranica, BGAges 18 years+ - NCT06336369Recruiting
Brown fat activity in Gilbert's syndrome
This study looks at brown fat activity in people with Gilbert's syndrome, a harmless condition that causes slightly high bilirubin levels. It compares them to people without the condition to see if the extra bilirubin affects brown fat, which may help with weight and metabolism.
ViennaAges 18–65 - NCT06338267Recruiting
Testing new sensors for Rett syndrome symptoms at home
This study tests new wearable sensors to track symptoms like heart rate and breathing in people with Rett syndrome. If you join, you'll use the sensors at home to help researchers see how symptoms change day to day.
Chicago, IllinoisAges Any age - NCT06338735Recruiting
High-frequency ultrasound for Sjögren's diagnosis
This study uses a special, very high-frequency ultrasound to take detailed images of the small glands that can be affected in Sjögren's syndrome. The goal is to see if this new ultrasound technique can help doctors diagnose Sjögren's more accurately.
PisaAges 18 years+ - NCT06339177Recruiting
HLH study looking at immune system and genes
This study is for people with hemophagocytic lymphohistiocytosis (HLH), a condition where the immune system becomes overactive. Researchers want to collect medical data and blood samples to better understand HLH and find better ways to diagnose and treat it.
Bethesda, MarylandAges 18–120 - NCT06346418Recruiting
Maternal genes and Beckwith-Wiedemann syndrome risk study
This study looks at how a mother's genes and chemical changes to DNA (called epimutations) may increase the risk of having a child with Beckwith-Wiedemann syndrome or affect a woman's ability to get pregnant and carry a baby to term. It aims to find genetic clues that could help explain these reproductive challenges.
MilanAges 18 years+ - NCT06366464RecruitingPhase 3
Study of a drug for sleepiness in Prader-Willi syndrome
This trial tests a medication called pitolisant to see if it helps reduce excessive daytime sleepiness in people with Prader-Willi syndrome. You or your loved one may be able to join if they have a confirmed diagnosis and a caregiver who can regularly help with study tasks.
Los Angeles, CaliforniaAges 6 years+ - NCT06371976Recruiting
Stress hormone system study after heart surgery
This study looks at how your body's stress hormone system (the HPA axis) works after heart surgery if you develop vasoplegic syndrome (a serious drop in blood pressure). The goal is to understand if giving extra steroids might help. If you are scheduled for heart surgery with a heart-lung machine, you may be able to join.
Paris, Île-de-France RegionAges 18 years+ - NCT06372717RecruitingPhase 1
Testing APL-4098 alone or combined for AML or MDS
This trial tests a new drug called APL-4098, given alone or with another medicine, for people with certain blood cancers (AML or MDS) that have come back or not responded to treatment. The goal is to see if it is safe and works well.
Clayton, VictoriaAges 18 years+ - NCT06373913Recruiting
PCSK9's role in kidney damage in nephrotic syndrome
This study looks at how a protein called PCSK9 might affect kidney damage in people with nephrotic syndrome. It is for adults admitted to Kolding Hospital and aims to better understand the link between this protein and kidney problems.
KoldingAges 18 years+ - NCT06373926Recruiting
Blood test for Annexin A2 in antiphospholipid syndrome
This study tests how a blood sample can help doctors better understand Antiphospholipid Syndrome (APS) by measuring a protein called Annexin A2 on white blood cells. It may lead to easier diagnosis and monitoring of this condition.
AmiensAges 18 years+ - NCT06376500Recruiting
Brain stimulation to help thinking after concussion
This study tests whether a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can help improve thinking and memory problems that some people have after a mild concussion. tDCS uses a small electrical current from scalp electrodes to gently activate parts of the brain.
Hung Hom, KowloonAges 18–65 - NCT06379646Recruiting
YTS109 cell therapy for autoimmune disease
This study tests a new cell therapy (YTS109) for people with autoimmune diseases like lupus or Sjogren's syndrome that have not improved or keep coming back after standard treatments. It aims to see if the treatment can help control the disease.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06379945Recruiting
Better MDS care through a national patient registry
This study is building a national platform in Spain to better understand MDS (a bone marrow disorder) and to help tailor treatments to each person. By joining, you help researchers learn more about your condition and how to manage it.
Badalona, BarcelonaAges 18 years+ - NCT06384430Recruiting
Shoulder impingement tests and ultrasound in diagnosis
This study looks at how certain shoulder tests and ultrasound images relate to each other in people with shoulder impingement (a common cause of shoulder pain). It aims to improve diagnosis and understand which tests work best.
MuğlaAges 18–70 - NCT06384846Recruiting
AI predicts heart attacks using white blood cells
This study tests whether an artificial intelligence tool can accurately predict a heart attack (acute coronary syndrome) by looking at the properties of your white blood cells. If successful, it could help doctors diagnose heart attacks faster from a simple blood sample.
Graz, Styria / SteiermarkAges 18 years+ - NCT06387524Recruiting
Eccentric exercises for knee pain in women
This trial studies if special leg exercises can improve walking in women with pain behind the kneecap. It may help if you have had knee pain for at least 2 months and it hurts during activities like stairs or sitting for a long time.
Rawalpindi, Punjab ProvinceAges 18–35 - NCT06393101RecruitingPhase 1
High-CBD cannabis extract for complex regional pain syndrome treatment
This study tests a high-CBD cannabis extract (BRC-002) to see if it can help reduce pain and improve health in people with Complex Regional Pain Syndrome (CRPS). Participants will not use opioids or other cannabis during the study.
La Jolla, CaliforniaAges 21–75 - NCT06394830RecruitingPhase 2
Testing VNX001 for bladder pain syndrome
This study tests a new treatment (VNX001) for people with interstitial cystitis or bladder pain syndrome (IC/BPS). You must have already taken part in an earlier study of this drug to join. The goal is to see if it safely reduces bladder pain.
Tucson, ArizonaAges 18 years+ - NCT06401811Recruiting
Turkish swallowing questionnaire study for Sjögren's syndrome
This study tests a Turkish version of a swallowing questionnaire (EAT-10) to see if it is reliable and accurate for people with primary Sjögren's syndrome. Taking part could help doctors better understand and track swallowing problems in this condition.
AnkaraAges 18 years+ - NCT06405438Recruiting
Mud therapy vs. paraffin wax for carpal tunnel syndrome
This trial compares two non-surgical treatments—mud therapy (peloid) and paraffin wax—for people with mild to moderate carpal tunnel syndrome. It aims to see which one better eases symptoms like numbness, tingling, and hand pain.
IstanbulAges 18–65 - NCT06409442Recruiting
Support and vibration for shoulder impingement
This study tests two non-invasive treatments—corrective external support (like special tape) and regional vibration—for people with subacromial impingement syndrome, a common cause of shoulder pain. It aims to see if these treatments can reduce pain and improve shoulder function.
Izmir, BalçovaAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.