Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT06887387Recruiting
Wearable devices to monitor Long QT Syndrome
This study tests whether wearable devices can help monitor Long QT Syndrome, a heart condition. It aims to make tracking your heart easier and more convenient than clinic visits.
LondonAges 18 years+ - NCT06889480Recruiting
Deep brain stimulation for severe Tourette syndrome
This trial tests a surgical procedure using deep brain stimulation to treat severe Tourette syndrome that hasn't improved with other treatments. It may help reduce tics by targeting specific areas in the brain.
Beijing, Beijing MunicipalityAges 18–60 - NCT06890013Recruiting
Heart artery function test after a heart attack
This study looks at how well the blood vessels in your arm relax after a heart attack. It uses an ultrasound test on your arm, a heart ultrasound, and some blood tests to see if this can help predict future heart problems.
ThessalonikiAges 18–85 - NCT06896981RecruitingPhase 2/Phase 3
Semaglutide for women with PCOS and obesity
This study tests if a weekly injection called semaglutide can help women with PCOS and obesity lose weight and improve their health. It is for women who do not have other serious medical conditions.
Dhaka, Dhaka DivisionAges 10–45 - NCT06899711Recruiting
A helmet after skull surgery to prevent sunken flap
This study tests whether wearing a custom-made external helmet after a large skull removal surgery can prevent the skin from sinking in. If you've had this surgery in the last two weeks and are being treated at a Johns Hopkins hospital, you may be eligible.
Baltimore, MarylandAges 18 years+ - NCT06900491Recruiting
Irritable Bowel Syndrome Regional Cohort Study
This study follows a group of people with irritable bowel syndrome (IBS) to learn more about the condition. You may join if you have been diagnosed with IBS and have had normal routine blood tests.
AmiensAges 18 years+ - NCT06909656Recruiting
Brain Activity Study in Tourette Syndrome with Deep Brain Stimulation
This study looks at brain activity in people with Tourette syndrome who are already receiving deep brain stimulation (a treatment that uses electrical pulses to help control tics). The goal is to learn more about the brain signals linked to tics, which could help improve future treatments.
BordeauxAges 16 years+ - NCT06912282Recruiting
Deep brain stimulation for Meige syndrome
This study tests if a new deep brain stimulation approach using one electrode on both sides of the brain can help control the muscle spasms of Meige syndrome. It is for people whose symptoms have not improved enough with standard treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06918834RecruitingPhase 2
Immediate vs bridging transplant for high-risk MDS
This trial compares getting a stem cell transplant right away versus getting other treatments first before transplant for people with high-risk myelodysplastic syndrome (MDS), a bone marrow disorder. It aims to see which approach leads to better outcomes.
Beijin, Beijing MunicipalityAges 18 years+ - NCT06918847Recruiting
Comparing myofascial release vs. cupping for restless leg and knee OA
This study compares two hands-on therapies – myofascial release (gentle stretching of connective tissue) and cupping (using suction cups on the skin) – to see which one better improves quality of life for people who have both restless leg syndrome and knee osteoarthritis. If you have both conditions, you may be able to join.
Karachi, SindhAges 40–70 - NCT06922370Recruiting
Study of bone and joint problems in Gitelman syndrome
This study looks at bone and joint problems in people with Gitelman syndrome, a rare kidney disorder. It aims to understand how this condition affects the body's bones and joints.
Hangzhou, ZhejiangAges Any age - NCT06923150Recruiting
MiniGo vs. standard care for bowel symptoms after rectal cancer surgery
This trial tests a small, portable device called MiniGo that uses a gentle water rinse to help control bowel symptoms after rectal cancer surgery. It may be an option for people who still have bothersome bowel problems despite trying other treatments.
AmiensAges 18 years+ - NCT06923488RecruitingPhase 1/Phase 2
Leflunomide and decitabine for returning MDS
This trial tests a new combination of two drugs—leflunomide and decitabine—for people with MDS that has come back or hasn't responded to treatment. The goal is to see if this combination can help control the disease.
Morgantown, West VirginiaAges 18 years+ - NCT06927947Recruiting
Helping families learn about inherited cancer risk
This study tests different ways to help family members of people with inherited cancer syndromes get genetic testing. It aims to improve cancer prevention and early detection.
Ann Arbor, MichiganAges 18 years+ - NCT06928662RecruitingPhase 1/Phase 2
Chemo, radiation, and donor stem cell transplant for high-risk blood cancers
This trial tests a strong chemotherapy and radiation combo followed by a donor stem cell transplant for people with aggressive blood cancers (like AML or MDS) that haven't responded to earlier treatments or came back. It aims to help prevent the cancer from returning.
Seattle, WashingtonAges 18 years+ - NCT06929598Recruiting
Shiatsu for chronic pain in children and teens
This study tests whether Shiatsu—a gentle, hands-on therapy—can help reduce chronic, non-inflammatory pain in children and adolescents. If you or your child have had long-term pain without inflammation and are already being seen at a specific pain clinic in Tel Aviv, this trial might be a good fit.
Tel Aviv, Tel AvivAges 10–18 - NCT06934798RecruitingPhase 4
Vasopressin vs. Noradrenaline for low blood pressure after heart surgery
This trial compares two medications, vasopressin and noradrenaline, to see which one works better at raising blood pressure in patients who develop dangerously low blood pressure (vasoplegic syndrome) within the first day after heart surgery. The goal is to find the safest and most effective treatment to stabilize blood pressure and help recovery.
São PauloAges 18 years+ - NCT06936319Recruiting
Body movements for POTS symptom control
This study tests simple body movements (like squeezing your legs or squatting) to see if they help control POTS symptoms. It may offer a non-drug way to manage dizziness and fast heart rate when standing.
Innsbruck, TyrolAges 18–80 - NCT06940596Recruiting
Comparing diets and therapies for irritable bowel syndrome
This study compares different dietary and behavioral treatments to find out which works best for different people with irritable bowel syndrome (IBS). You'll be asked to follow a specific treatment program to see how it affects your symptoms.
Melbourne, VictoriaAges 18 years+ - NCT06940609RecruitingPhase 2
Brain scan study for Long COVID brain fog
This trial studies if brain scans can help understand 'brain fog' in Long COVID. It also looks at how a gentle magnetic stimulation might affect symptoms. If you have ongoing thinking problems after COVID, this study may help find new ways to help.
Albuquerque, New MexicoAges 18–80 - NCT06943170Recruiting
Aerobic exercise with or without a low calorie diet for teens with Down syndrome
This trial studies how aerobic exercise, alone or combined with a low calorie diet, affects body fat and weight in children with Down syndrome who are overweight or obese. The goal is to find a safe, effective way to help manage weight.
Lahore, Punjab ProvinceAges 8–16 - NCT06943508Recruiting
Nordic walking for balance in children with Down syndrome
This study tests whether a special walking program (Nordic walking with poles) can help children with Down syndrome improve their balance and leg strength. It may be a good fit for children who can walk but have balance difficulties.
Lahore, Punjab ProvinceAges 8–13 - NCT06951386Recruiting
Can a daily drink improve heart and metabolic health?
This trial tests whether taking a daily drink containing short-chain fatty acids can improve risk factors for metabolic syndrome, like belly fat, high blood sugar, or high blood pressure. It might help if you are at risk but not yet taking medications for these conditions.
Leuven, Vlaams-BrabantAges 18–65
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.