Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06951516Recruiting
Can simple language help young kids with Down syndrome learn?
This study looks at whether using simpler language helps children with Down syndrome understand and learn better. It is for children ages 2 to 7 who speak English as their main language.
East Lansing, MichiganAges 2–7 - NCT06952413RecruitingPhase 2
Rituximab for chronic fatigue syndrome (ME/CFS) trial
This trial tests if rituximab, a drug that affects the immune system, can help people with ME/CFS. You'll receive the drug in the hospital and be monitored for safety and improvement.
Kodaira, TokyoAges 18–65 - NCT06955052Recruiting
Maze activity for balance and walking in Down syndrome
This study tests a fun activity program called 'Minds In Motion The Maze' to see if it helps improve balance and walking in children with Down syndrome.
Lahore, Punjab ProvinceAges 8–12 - NCT06956755Recruiting
Registry for MDS and treatment-related leukemia
This study collects information from people with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that developed after cancer treatment. It does not test a new drug but helps doctors learn more about these conditions.
RouenAges 18 years+ - NCT06958406Recruiting
Brain-heart connection after head injury
This study uses brain scans (MRI) to understand how a traumatic brain injury can affect the heart. It may help find better ways to treat the brain-heart connection after a head injury.
ShanghaiAges 18–80 - NCT06960746Recruiting
Lifestyle change for sleep apnea, metabolic syndrome, and impotence
This trial tests whether changing your lifestyle can help men with sleep apnea, metabolic syndrome, and erectile dysfunction. It studies how improving diet and exercise might improve these conditions together.
Giza, DokkiAges 40–50 - NCT06961864Recruiting
Brain function in visual snow syndrome
This study uses visual tests and brain scans to understand how the brain processes vision in people with visual snow syndrome compared to those without. It may help researchers learn more about what causes this condition.
Minneapolis, MinnesotaAges 18–60 - NCT06962345Recruiting
Testing a new vaginal gel for menopause symptoms
This trial is testing a new non-hormonal gel for vaginal dryness and discomfort after menopause. It aims to see if the gel improves quality of life.
Madrid, MadridAges 40–70 - NCT06966752Recruiting
Comparing two breathing supports for preterm babies with breathing problems
This study compares two types of breathing support (CPAP and NIPPV) for preterm babies with breathing problems. It aims to find which method works better for helping babies breathe easier.
Vilnius, Vilnius CountyAges birth–10 months - NCT06967038RecruitingPhase 1/Phase 2
Natural killer cell therapy for high-risk lymphoma with Sjogren's syndrome
This trial tests a new type of immune cell therapy using natural killer cells to treat people who have both high-risk lymphoma and primary Sjogren's syndrome. The goal is to see if these cells can safely and effectively fight the lymphoma while managing the autoimmune condition.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06967831Recruiting
Testing existing drugs for mitochondrial disorders
This trial looks at whether drugs already approved for other conditions might help people with Leigh syndrome, a rare mitochondrial disorder. Researchers will study cells made from your skin to see how these drugs work.
Düsseldorf, North Rhine-WestphaliaAges Any age - NCT06971874Recruiting
Sleep apnea and kidney disease: A study on outcomes
This trial looks at how obstructive sleep apnea affects people with chronic kidney disease (stages 3-4). It aims to help understand the connection between these conditions and guide better care.
Guangzhou, GuangdongAges 18–75 - NCT06973304RecruitingPhase 3
Teduglutide for short bowel syndrome in Chinese adults
This study tests a medicine called teduglutide for adults in China with short bowel syndrome who need long-term IV nutrition or fluids (parenteral support). The goal is to see if teduglutide can help them reduce or stop the need for these IV treatments.
Changping, Beijing MunicipalityAges 18 years+ - NCT06977321Recruiting
Taping vs mud therapy for carpal tunnel syndrome
This study tests whether taping therapy (kinesiotaping) or a mud pack treatment (peloidotherapy) can help reduce pain and improve function for people with mild to moderate carpal tunnel syndrome. It may be an option if you want non-surgical, drug-free relief.
KonyaAges 1.5 years–5.4 years - NCT06977672Recruiting
Yoga for writing skills in children with Down syndrome
This study tests whether a simple yoga pose (Downward Dog) can help children with Down syndrome improve the fine motor skills they need for writing. It is designed for children ages 4 to 8 who can stand and walk on their own.
Lahore, Punjab ProvinceAges 4–8 - NCT06978647RecruitingPhase 1
YTS109 cell therapy for stubborn autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with certain autoimmune diseases like lupus that have not improved with standard treatments. It aims to see if this therapy can help control disease activity.
Beijing, Beijing MunicipalityAges 18–65 - NCT06983496Recruiting
Telehealth help for ICU recovery after critical illness
This trial tests if a pharmacist and intensive care doctor team can help veterans recover at home after a serious ICU stay, using telehealth visits to manage medications and health issues.
Gainesville, FloridaAges 18–89 - NCT06988189Recruiting
Finding hidden heart rhythm problems in adults
This study looks for hidden heart rhythm problems in adults. It involves simple tests to find conditions that might otherwise go unnoticed.
LondonAges 18–100 - NCT06992752Recruiting
Trial on breathing problems in people with thoracic outlet syndrome
This study looks at whether people with thoracic outlet syndrome (TOS) have different breathing patterns and how that might relate to their symptoms. If you have had TOS pain for more than 6 months, you may be able to help researchers understand this condition better.
Ankara, AltındağAges 18–65 - NCT06996509Recruiting
Noninvasive breathing support for Guillain-Barré syndrome
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Asyut, AssuitAges 18 years+ - NCT07001111Recruiting
Taping therapy for cubital tunnel syndrome pain
This trial tests if a special tape placed on the arm can help reduce pain and improve symptoms in people with cubital tunnel syndrome. It may be a good option if you have arm pain and have not had surgery or certain injections recently.
Istanbul, UskudarAges 18–65 - NCT07002892Recruiting
Injection treatments for moderate carpal tunnel syndrome
This study compares two injection treatments (corticosteroid with dextrose versus ozone) for carpal tunnel syndrome. It may help if your CTS is moderate and other treatments haven't worked.
AnkaraAges 18–65 - NCT07004881Recruiting
Comparison of two hand-on knee treatments for kneecap pain
This trial compares two gentle physical therapy techniques (Mulligan and Maitland mobilization) to see which works better for kneecap pain. If you have had knee pain for at least 2 months and it hurts with stairs, sitting, or squatting, this study may help find the best treatment for you.
IslamabadAges 18–40 - NCT07013331Recruiting
Brain scan study for Dravet syndrome
This study uses a special PET-MRI scan to look at a brain chemical pathway linked to serotonin (a mood-regulating substance) in people with Dravet syndrome or certain types of epilepsy, and in healthy volunteers. It may help understand how the brain works in these conditions.
Bron, RhoneAges 18–60
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.