Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06612242Recruiting
Early vs. late tracheostomy in Guillain-Barre patients
This trial looks at whether having a tracheostomy (a breathing tube placed through the neck) earlier or later helps people with Guillain-Barre syndrome who need a breathing machine. It reviews past cases to see which timing leads to better recovery.
Kfar SabaAges 18 years+ - NCT06455332Recruiting
Optic nerve test to predict MS after first symptoms
This study looks at how early damage to the optic nerve (the nerve that connects your eye to your brain) might predict future multiple sclerosis (MS) in people who have just had their first neurological symptoms (called a clinically isolated syndrome). You will have an MRI of your eyes and a special eye scan to see if these tests can help doctors know who is more likely to develop MS.
LilleAges 18–55 - NCT06593977Recruiting
Dynavisc gel for pain after repeat carpal tunnel surgery
This trial tests a gel called Dynavisc to see if it reduces pain when placed in the wrist during a second surgery for carpal tunnel syndrome. It may help people who still have pain after their first surgery.
Leuven, BelgiumAges 18–65 - NCT06599762RecruitingPhase 2
Tranexamic acid for bleeding in MDS and AML
This trial tests if tranexamic acid, a medicine that helps blood clot, can reduce bleeding in people with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) who have very low platelet counts and are receiving less-intensive chemotherapy.
Winnipeg, ManitobaAges 18 years+ - NCT06598449RecruitingPhase 4
Safety of fenfluramine in children under 2 with Dravet syndrome
This trial tests the safety of a medicine called fenfluramine for children under 2 years old with Dravet syndrome. It aims to see if fenfluramine can help control seizures in very young children.
Aurora, ColoradoAges 1–2 - NCT06598709Enrolling by invitation
International study on breathing tube removal in ARDS
This study looks at how doctors safely remove breathing tubes from patients with lung injury (ARDS). It aims to find ways to improve decisions about when to take the tube out.
HiroshimaAges 16 years+ - NCT06577441RecruitingPhase 2
Adding enasidenib to usual care for higher-risk MDS with IDH2 mutation
This trial tests whether adding enasidenib (a targeted pill) to the standard chemotherapy (cedazuridine-decitabine) works better than the chemotherapy alone for people with higher-risk myelodysplastic syndrome (MDS) whose cells have a specific change in the IDH2 gene.
Berkeley, CaliforniaAges 18 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06578390Recruiting
Testing a smartphone app for sleep apnea diagnosis
This trial tests whether a smartphone app (Apneal®) can accurately diagnose sleep apnea during a routine sleep study. If you are already going to have a sleep study, you may be able to help test this device.
Aix-en-ProvenceAges 18 years+ - NCT06577519RecruitingPhase 3
Study of vicagrel for heart attack patients getting stents
This trial tests a new medicine called vicagrel for people who have had a heart attack or unstable angina and are getting a stent. The goal is to see if it works better than standard treatments to prevent future heart problems.
Shenyang, LiaoningAges 18–80 - NCT05052736Recruiting
Noninvasive brain/nerve stimulation for early CRPS type I
This trial studies a noninvasive stimulation treatment to help people with early-stage complex regional pain syndrome (CRPS) type I. It may help calm nerve-related pain, especially soon after symptoms begin.
Las Palmas de Gran Canaria, Palmas, LasAges 18 years+ - NCT06569095Recruiting
Study of stem cells in myelodysplastic syndrome
This study looks at special stem cells in the blood or bone marrow of people with myelodysplastic syndromes (MDS). It aims to better predict how the disease might progress and help guide treatment decisions.
BeijingAges 15–70 - NCT06573723Recruiting
Rare disease registry at Hospital Italiano
This study collects information from patients with certain rare diseases to better understand them. If you have one of these conditions and receive care at Hospital Italiano de Buenos Aires, you may be able to join.
Buenos Aires, Buenos AiresAges Any age - NCT05889559Recruiting
Testing a fluid drainage method to detect leg pressure problems
This study looks at a special drainage measurement (“tissue ultrafiltration”) to better detect and treat acute compartment syndrome, a dangerous increase in pressure in the leg after major injury. It may help doctors identify who needs urgent treatment and improve outcomes after severe leg fractures or crush injuries.
Baltimore, MarylandAges 18–60 - NCT05963191Recruiting
Test camera bowel scan for early Lynch syndrome lesions
This study tests a special CAD-EYE system to help detect abnormal (potentially cancer-related) growths during colonoscopy in people with Lynch syndrome. It may improve how reliably clinicians find lesions early, when treatment can be easier.
ParisAges 18–90 - NCT06041204Recruiting
Thyroid hormone plus letrozole for PCOS and mild hypothyroidism
This trial tests whether adding a low-dose thyroid hormone (levothyroxine) to the standard fertility treatment letrozole improves pregnancy rates in women with both PCOS and mild hypothyroidism. It may help if you have trouble getting pregnant and have these two conditions.
CairoAges 20–40 - NCT06546189Recruiting
Probiotics for overactive bladder treatment
This study tests whether a daily probiotic supplement (Lactobacillus) can help reduce overactive bladder symptoms. It compares the supplement to a placebo in a randomized trial.
ViennaAges 18 years+ - NCT06545721Recruiting
Weight changes and hormone health in PCOS
This study looks at how weight changes affect hormone levels and insulin resistance in women with PCOS. It may help understand if weight cycling is harmful or helpful.
Beijing, Beijing MunicipalityAges 18–45 - NCT06548230RecruitingPhase 1/Phase 2
Nadunolimab plus azacitidine for MDS and AML
This trial tests a new combination of drugs (nadunolimab plus azacitidine, sometimes with venetoclax) for patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that has not been treated much or has come back. The goal is to see if this combination can control the disease better.
Houston, TexasAges 18 years+ - NCT06536543Recruiting
Lung imaging to check over-inflation in ARDS patients lying on their stomach
This trial uses a special lung imaging belt (EIT) to see if the lungs are over-inflated in patients with severe breathing problems (ARDS) when they lie on their stomach. It aims to help doctors adjust ventilator settings for better lung protection.
BayonneAges 18 years+ - NCT06334692Recruiting
Autoantibody study in nephrotic syndrome
This study looks for specific proteins (autoantibodies) in your blood that may be linked to certain kidney diseases. It aims to better understand the immune system's role in minimal change disease and FSGS, which could lead to better treatments.
Ranica, BGAges 18 years+ - NCT06529731RecruitingPhase 2
Interferon-Gamma and Donor Cells for Relapsed Leukemia After Transplant
This trial tests combining a protein called interferon-gamma with an infusion of donor white blood cells to treat AML or MDS that returned after a stem cell transplant. The goal is to see if this combination helps the donor cells attack the cancer more effectively.
St Louis, MissouriAges 18 years+ - NCT06526741Recruiting
Alport Syndrome Patient Registry
This registry collects health information from people with Alport syndrome to help researchers better understand the condition and improve future treatments.
Scottsdale, ArizonaAges birth+ - NCT06527768Recruiting
Helping with metabolic syndrome and kidney disease through lifestyle changes
This study tests a program that uses WeChat to help people with metabolic syndrome and chronic kidney disease make healthy lifestyle changes. They want to see if this support can improve health and slow down kidney problems.
Chengdu, SichuanAges 18 years+
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.