Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07569731Recruiting
Understanding Fibrous Dysplasia Through Patient Data and Tissue
This study collects information from patients with fibrous dysplasia (a bone condition where normal bone is replaced by fibrous tissue) and related syndromes to better understand the disease. Researchers will review your medical records, imaging scans, and stored tissue samples to learn more about how the disease develops and progresses.
Bologna, BOAges Any age - NCT07571096Recruiting
PCOS and Blood Clotting Risk Assessment Study
This study helps doctors better understand polycystic ovary syndrome (PCOS)—a hormonal condition affecting ovulation—and how it relates to blood clotting problems. Researchers will collect blood samples and health information to create a risk assessment tool.
Guangzhou, GuangdongAges 14–45 - NCT07573371Recruiting
Understanding bowel changes after rectal cancer surgery
This study helps doctors better understand and treat bowel control problems that can happen after rectal cancer surgery or other rectal treatments. If you've had this surgery or treatment, the study team wants to learn more about your recovery and test new ways to help.
AalborgAges 18 years+ - NCT07578831Recruiting
Neck Pain Relief: Comparing Two Exercise Methods
This study compares two types of therapeutic exercises—Kendall and Feldenkrais—to help reduce neck pain and improve posture in people with upper crossed syndrome (a common postural condition where neck and shoulder muscles become tight and weak). You'll do one type of exercise program to see which helps your neck pain and function better.
Lahore, Punjab ProvinceAges 20–50 - NCT07578922Recruiting
Bean Bag Game for Balance and Walking in Children With Down Syndrome
This study tests whether playing a bean bag tossing game helps children with Down syndrome improve their balance and walking ability. The game is designed to be fun while building strength and coordination.
Lahore, Punjab ProvinceAges 5–17 - NCT07584083RecruitingPhase 2
Anifrolumab for Primary Antiphospholipid Syndrome
This trial tests a new drug called anifrolumab in adults with primary antiphospholipid syndrome (a blood clotting disorder). The drug may help reduce clotting and related complications by working with your immune system.
Athens, GreeceAges 18–70 - NCT07584278Recruiting
Probiotics and Biomarkers for Irritable Bowel Syndrome
This study tests whether probiotics (beneficial bacteria) can help reduce irritable bowel syndrome (IBS) symptoms and change certain markers in your gut. You'll take a probiotic supplement for 12 weeks while researchers track how your symptoms and gut health change.
GothenburgAges 18 years+ - NCT07585578Recruiting
Understanding Recovery Problems After Intensive Care
This study looks at patients who spent at least 2 days in the ICU (intensive care unit) to understand the physical, mental, and emotional challenges they face during recovery. Researchers will ask you questions about your health and function to identify what kind of support might help you feel better.
Huaibei, AnhuiAges 18 years+ - NCT07598643RecruitingPhase 2
Immune System Treatment to Help Down Syndrome Development
This study tests a medication called tofacitinib that modulates the immune system in children and young adults with Down syndrome aged 6–22 years. The goal is to see if it can improve brain development and overall health outcomes over 6 months.
Aurora, ColoradoAges 6–22 - NCT07599306Recruiting
Telehealth Rehabilitation for Heart Patients After ICU Recovery
This study tests whether supervised remote rehabilitation exercises can help people recover better after a long ICU stay. Many patients struggle with weakness, memory problems, or mood changes after intensive care—this trial aims to improve those symptoms through video-guided therapy.
Milan, MilanoAges 30–75 - NCT07604103RecruitingPhase 3
Heart Attack and Pneumonia Recovery Study With Vaccination
This study looks at blood markers (special proteins) in patients who have had both a heart attack and pneumonia, to see how vaccination affects recovery. The goal is to understand whether flu and pneumonia vaccines are safe and helpful for people recovering from these two serious conditions together.
Malang, East JavaAges 18–65 - NCT07605481Recruiting
Managing Dumping Syndrome After Esophageal Cancer Surgery
This study looks at dumping syndrome—a condition where food moves too quickly from your stomach after esophageal cancer surgery—and tests ways to help manage its symptoms like sweating, dizziness, and abdominal discomfort.
Seoul, Gangnam-gu Irwon-Ro 81Ages 18 years+ - NCT07607730Recruiting
Group therapy for emotion control in teens with Prader-Willi syndrome
This study tests a group therapy program designed to help teenagers with Prader-Willi syndrome (a genetic condition) learn better emotional control and regulation skills. Your teen and family would attend weekly group sessions to practice tools for managing emotions like anger or frustration.
Kansas City, MissouriAges 13–17 - NCT07608809Recruiting
Blood Flow Restriction Training vs. Pilates for Shoulder Pain
This study compares two exercise approaches—one using special wraps to limit blood flow during exercise, and standard Pilates—to treat shoulder impingement syndrome (a common condition causing shoulder pain with overhead movements). The goal is to see which method works better at reducing pain and improving shoulder function.
RāshidAges 4 months–1.1 years - NCT07625332RecruitingPhase 2/Phase 3
Galantamine for Metabolic Syndrome in Spinal Cord Injury
This study tests whether a medication called galantamine can help improve metabolic syndrome (a cluster of health conditions including obesity, high blood sugar, and high cholesterol) in people with chronic spinal cord injury. The goal is to see if this treatment can reduce health risks and improve overall wellness.
West Orange, New JerseyAges 21–75 - NCT07625579Recruiting
Collaboration for Down Syndrome Progress Research Study
This research study aims to better understand Down syndrome by collecting health information, family history, and sometimes brain imaging or sleep data from children and adults with Down syndrome and their families. The goal is to advance knowledge that could improve health and development for people with Down syndrome.
Orange, CaliforniaAges Any age - NCT07628387Recruiting
Exercise Types for Restless Legs in Pregnancy
This study compares two types of exercise—aerobic (heart-pumping) and muscle relaxation—to help pregnant women with restless leg syndrome sleep better and feel less tired. Restless leg syndrome causes uncomfortable sensations in the legs, especially at night, which disrupts sleep during pregnancy.
Lahore, Punjab ProvinceAges 20–40 - NCT07630207Recruiting
Blood Vessel Health Study in Young Adults with Down Syndrome
This research study looks at how blood vessels work in young adults with Down syndrome compared to those without it. By understanding differences in blood vessel function, researchers hope to find ways to improve heart and circulation health for people with Down syndrome.
Las Vegas, NevadaAges 18–35 - NCT07633236RecruitingPhase 3
Olanzapine to prevent appetite and weight loss during cancer chemotherapy
This study tests whether olanzapine, a medication that can increase appetite, helps prevent severe appetite loss and muscle wasting in patients with ovarian or stomach cancer who are receiving chemotherapy before surgery. The goal is to help patients maintain nutrition and strength during treatment.
MoscowAges Any age - NCT07635394Recruiting
Pregabalin for Irritable Bowel Syndrome Relief
This study tests whether pregabalin, a nerve-pain medication, can help reduce irritable bowel syndrome (IBS) symptoms like abdominal pain and irregular bowel habits. Researchers want to see if it's safe and effective for people with mild-to-moderate IBS.
Beijing, Beijing MunicipalityAges 18–70 - NCT07638137Recruiting
Advanced Heart Catheter Testing for Stent Patients With Chest Pain
This study tests a detailed diagnostic procedure during heart catheterization for patients who previously had stents placed and now have chest pain or signs of heart stress. The goal is to better understand blood flow in treated arteries to guide treatment decisions.
Leganés, MadridAges 18 years+ - NCT07642089Recruiting
Stretching and strength training for restless legs in pregnancy
This study tests whether gentle stretching and strength exercises can help pregnant women with restless leg syndrome—a condition that causes uncomfortable sensations in the legs and disrupts sleep. The goal is to see if these exercises reduce symptoms and improve sleep quality during pregnancy.
Lahore, Punjab ProvinceAges 18–35 - NCT07643896Recruiting
Blood test for pregnancy risk assessment using fetal cells
This study tests a new blood test that looks for fetal cells in your bloodstream to check your baby's health during pregnancy. The test is non-invasive—just a regular blood draw—and aims to help identify pregnancy risks earlier than traditional methods.
Phoenix, ArizonaAges Any age - NCT07645014Recruiting
Physical Therapy for PCOS Pain and Irregular Periods
This study compares two hands-on physical therapy techniques to see if they help reduce period pain and improve symptoms in women with PCOS (a hormone condition affecting the ovaries). You'll receive either neurodynamic stretching or myofascial release therapy to see which works better.
Lahore, Punjab ProvinceAges 18–35
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.