Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06757296Recruiting
Endoscopic revision of sleeve gastrectomy for reflux or poor weight loss
This study tests a new, less invasive way to convert a sleeve gastrectomy into a different type of weight-loss surgery (SASI) in people who have ongoing gastroesophageal reflux or haven't lost enough weight. The goal is to see if this endoscopic procedure can improve reflux and help with weight loss without the need for a traditional surgery.
SingaporeAges 21–65 - NCT06776263Recruiting
Breathing problems after COVID-19 study
This study looks at people who have ongoing breathing issues after a COVID-19 infection. It tests a simple questionnaire to see if you have dysfunctional breathing (abnormal breathing patterns) and may help guide treatment.
Stockholm, SolnaAges 18 years+ - NCT06829940Recruiting
Baduanjin exercise for long COVID fatigue
This trial tests whether Baduanjin, a gentle mind-body exercise, can help people under 50 with long-standing chronic fatigue that's worse after COVID-19. It aims to see if this safe, low-impact practice improves energy and daily life without needing extra treatments.
CairoAges 18–50 - NCT07391605RecruitingPhase 2
Descartes-08 for treatment-resistant myositis
This trial tests a new treatment called Descartes-08 for people with dermatomyositis or antisynthetase syndrome whose disease hasn't responded well to standard therapies. It aims to see if this treatment can help control muscle and skin symptoms.
Orange, CaliforniaAges 18 years+ - NCT07391306RecruitingPhase 2/Phase 3
New treatment for interstitial cystitis without Hunner's lesions
This trial is testing a new treatment for people with painful bladder syndrome (interstitial cystitis) who do not have Hunner's lesions in their bladder. It aims to see if the treatment can help reduce pelvic pain and frequent urination.
MoscowAges 18–65 - NCT07390851Recruiting
Magnesium with lidocaine for jaw and neck muscle trigger points
This trial tests whether adding magnesium to lidocaine makes trigger point injections more effective for jaw, face, or upper shoulder pain. The results will be measured by pain scales and muscle activity tests.
Giza, Giza GovernorateAges 18–70 - NCT07394530Recruiting
Comparing two IVF stimulation methods for women with PCOS
This trial compares two types of ovarian stimulation protocols (PPOS and antagonist) for women with PCOS undergoing IVF to see which leads to better outcomes. If you have PCOS and are planning IVF, this study may help find the best approach for you.
Hanoi, HanoiAges 18–40 - NCT07390422Recruiting
PulsENDO for diabetes and fatty liver
This trial tests a new endoscopic procedure (pulsENDO) for people with type 2 diabetes and fatty liver disease whose blood sugar remains high despite taking diabetes pills. It aims to see if this treatment can improve blood sugar control and liver health.
ShatinAges 18–70 - NCT07396480RecruitingPhase 3
Add-on Venetoclax before stem cell transplant for AML/MDS
This trial tests adding venetoclax to the usual chemotherapy (fludarabine and melphalan) given before a stem cell transplant for older adults with AML or MDS. The goal is to see if the combination helps prevent the disease from coming back after transplant.
Fuzhou, FujianAges 50–75 - NCT06045351RecruitingPhase 1
Vitamin D shots for women with PCOS and low vitamin D
This trial tests whether vitamin D injections can help females with polycystic ovary syndrome (PCOS) who also have low vitamin D levels. Participants will receive the injection and be monitored for changes in their condition.
Karachi, SindhAges 18–45 - NCT05991908RecruitingPhase 3
Comparing chemotherapy regimens before stem cell transplant for blood cancers
This trial is testing two different chemotherapy regimens (with one or two alkylating agents) before a stem cell transplant for people with acute myeloid leukemia or myelodysplastic syndrome. The goal is to find which conditioning treatment is safer and more effective.
Fuzhou, FujianAges 16–55 - NCT06568159Recruiting
Sleep apnea treatment in heart patients
This study looks at how well people with heart disease or high heart risk follow their sleep apnea treatment, comparing a mouth device (MAD) to a CPAP machine. It aims to find which treatment works better for daily use.
MontpellierAges 18 years+ - NCT06832852Recruiting
Comparing cost-effective care for muscle and joint pain
This study compares different models of care to find the most cost-effective way to treat common muscle and joint problems (like back, neck, knee, or shoulder pain). It looks at which approach works best for patients with persistent pain to guide future treatment decisions.
Québec, QuebecAges 18–65 - NCT03989778RecruitingPhase 2
Vitamin D for PCOS with low vitamin D
This Phase 2 study tests whether vitamin D can improve hormone balance and infertility-related problems in people with PCOS who have low vitamin D. You may be able to join if you’re between 18 and 36, have primary infertility, and meet specific PCOS and vitamin D blood test levels.
Karachi, SindhAges 18–36 - NCT05822193Recruiting
Study of long COVID in Brazil
This study looks at how often “post-COVID-19 condition” (long COVID) happens, what factors are linked to it, and how much it affects people’s daily lives. It may help researchers better understand long COVID and who is most impacted.
Cachoeirinha, Rio Grande do SulAges 18 years+ - NCT06101862Recruiting
CT scan vs. angiogram for certain heart attacks
This trial compares two ways to look at heart arteries: a CT scan (noninvasive) versus a traditional angiogram (a tube put into an artery). The goal is to see which is better for people having a certain type of heart attack.
Copenhagen, HellerupAges Any age - NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT06827184Recruiting
Best time for lying on stomach with severe lung failure
This trial is for people with severe lung failure (ARDS) who need a breathing machine. It tests how long lying on your stomach (prone position) helps improve breathing, by measuring changes in your body's oxygen levels and other vital signs.
TaipeiAges 18 years+ - NCT07383220Recruiting
Electrical stimulation and exercise for resistant high blood pressure
This trial tests if adding electrical stimulation to exercise can improve blood flow in people with resistant high blood pressure. It may help those whose blood pressure stays high despite taking multiple medications.
Port Said, Port Said GovernorateAges 50–60 - NCT07385196Recruiting
Understanding symptoms after ileorectal surgery
This study observes patients who have had a surgery connecting the small intestine to the rectum (ileorectal anastomosis) or who kept their rectum after colon surgery. Researchers want to better understand what symptoms these patients experience, which could help improve care.
DiyarbakırAges 18 years+ - NCT07383883Recruiting
Asthma Study Using Tongue and Pulse Patterns
This study uses tongue and pulse information to better understand asthma in children. It may help doctors personalize treatment and improve care.
ShanghaiAges 5–18 - NCT04251078Recruiting
Blood tests to track mutations in lower-risk MDS
This study uses repeated blood samples to watch how genetic changes in your blood evolve in lower-risk myelodysplastic syndrome (MDS). It may help doctors understand what mutation changes mean over time for people not on strong cancer-fighting treatments.
Badalona, BarcelonaAges 18 years+ - NCT05908227Recruiting
Testing nasal high-flow settings in stable preterm babies
This study tests how different nasal high-flow “flow strength” settings affect breathing stability in preterm infants. It may help clinicians choose settings that keep heart rate and breathing steadier.
Mainz, Rhineland-PalatinateAges 5 months–7 months - NCT06839690Recruiting
Comparing two exercises for De Quervain tenosynovitis
This study compares two types of exercises (sub-maximal isometric training vs eccentric training) to see which one helps more with thumb pain and tenderness caused by De Quervain tenosynovitis. You may qualify if you have had thumb pain for at least 3 weeks and meet certain diagnostic tests.
Rawalpindi, Punjab ProvinceAges 21–50
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.