Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,871 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05156983RecruitingPhase 3
Reversal drug for urgent surgery in people on Factor Xa blood thinners
This Phase 3 study tests TAK-330, a reversal (blocking) medicine, to reduce bleeding risk during urgent surgery for adults taking Factor Xa inhibitors like rivaroxaban, apixaban, or edoxaban. It’s for situations where surgery can’t wait and doctors need a fast way to restore normal clotting.
Arkansas City, ArkansasAges 18 years+ - NCT05160987Recruiting
Sedation choice for ICU patients on breathing machines
This study compares two sedation medicines—remimazolam vs midazolam—for very sick ICU patients who are on a breathing machine. It looks at whether one sedative works better or is safer for keeping patients comfortable while they’re critically ill.
Guangzhou, GuangdongAges 18–80 - NCT05165056Recruiting
Light therapy to prevent vaginal side effects from radiation
This study tests whether photobiomodulation (a light-based therapy) can help prevent and lessen vaginal problems caused by radiation for endometrial cancer. If you get radiation to the pelvis, the trial aims to improve comfort and reduce tightening or damage over time.
Genk, LimburgAges 18 years+ - NCT05166954Recruiting
Bariatric surgery and heart function in people with high blood pressure
This study looks at whether bariatric (weight-loss) surgery improves heart function in people who have high blood pressure. You may be able to join if you’re already a bariatric surgery patient at the study hospital and meet the health and medication criteria.
Beijing, Beijing MunicipalityAges 17–70 - NCT05168462RecruitingPhase 4
Lower blood pressure goal in heart-attack shock patients
This study compares two blood pressure targets in people with cardiogenic shock after a heart attack. It looks at whether the lower target can improve outcomes and help evaluate treatment costs.
AmsterdamAges 18 years+ - NCT05168124Recruiting
Therapy or short breaks for chronic fatigue syndrome (CFS/ME)
This study tests whether Acceptance and Commitment Therapy (ACT) or doing brief “micro breaks” can improve symptoms in people with CFS/ME. It checks safety and whether you can follow the online program over the study period.
ZurichAges 18–55 - NCT05170230Recruiting
Terlipressin or carbetocin shots to reduce bleeding in fibroid surgery
This study compares two different medications given as shots during laparoscopic fibroid (myomectomy) surgery. The goal is to see which shot better reduces blood loss and helps keep hemoglobin (a blood oxygen-carrying protein) from dropping too much.
MaadiAges 16–45 - NCT05182892Recruiting
Reducing speech side effects from DBS using speech recordings
This study tests whether automated analysis of your speech can help reduce speech problems caused by deep brain stimulation (DBS) in Parkinson’s disease. It may help your team adjust DBS settings to improve how you speak while keeping Parkinson symptoms controlled.
PragueAges 18 years+ - NCT05183074Recruiting
MRI-guided focused radiation for prostate cancer
This trial tests a newer way to plan and deliver radiation for prostate cancer using real-time MRI guidance. It may help by aiming high-dose treatment precisely while treating nearby disease and (in some cases) limited metastatic spots.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05187000Recruiting
Personalized brain stimulation for patients in coma after brain injury
This study tests whether personalized repetitive brain stimulation (rTMS) can improve symptoms in people diagnosed with disorders of consciousness after a recent brain injury. It compares treatment in a steady, safe way and checks whether the stimulation target matches your brain scan.
Guangzhou, GuangdongAges 18–70 - NCT05187650Recruiting
Powered exoskeleton plus electrical stimulation for incomplete spinal cord injury
This trial tests whether a powered walking exoskeleton together with electrical muscle stimulation (FES) can improve walking and movement in people with long-term, incomplete spinal cord injury. It may help you stand and walk more safely and effectively than standard care alone.
Nottwil, Canton of LucerneAges 18 years+ - NCT05192876Recruiting
Review of outcomes and side effects during radiation treatment
This study collects information about results and side effects from people receiving radiation therapy at a specific hospital. It may help improve how radiation treatment is planned and monitored in the future.
Winterthur, Canton of ZurichAges 16–105 - NCT05194098Recruiting
EEG and brain stimulation study for depression reward symptoms
This study uses non-invasive brain stimulation (like TMS) and EEG brain recordings to measure how the brain’s “reward” system works in people with major depression. It may help researchers understand which stimulation approaches best affect depression-related reward processing.
San Francisco, CaliforniaAges 18–65 - NCT05195034Recruiting
Dexmedetomidine to prevent confusion after awake brain surgery
This trial looks at whether a medication called dexmedetomidine can reduce “postoperative delirium,” a temporary period of confusion after awake brain surgery. If you have the type of surgery the study focuses on, this could help your recovery and mental clarity afterward.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05203250Recruiting
Registry for people treated with heavy particles at CNAO
This registry collects information from people who received heavy particle treatments at the CNAO center. It helps researchers understand outcomes over time, as long as you can understand the study and agree in writing.
PaviaAges Any age - NCT05203640Recruiting
Strength exercise study for post-menopausal type 1 diabetes
This study checks whether a resistance (strength) exercise program changes blood sugar levels in post-menopausal women with type 1 diabetes. You may be asked to do supervised lab-based exercise sessions near the University of Alberta.
Edmonton, AlbertaAges 45–75 - NCT05211375RecruitingPhase 3
Compare two weight-loss surgeries for type 2 diabetes control
This Phase 3 trial compares sleeve gastrectomy versus a different bypass-style operation to improve blood sugar in adults with type 2 diabetes. It may help some people lower blood sugar and diabetes medication needs, but you must meet specific safety and health criteria.
Seongnam-siAges 18 years+ - NCT05212454RecruitingPhase 3
Capecitabine added after surgery for high-risk ER-positive breast cancer
This Phase 3 study tests whether adding capecitabine (a chemotherapy pill) after breast cancer surgery can lower the chance the cancer comes back. It targets people with hormone-receptor–positive and HER2-negative breast cancer who are considered “high risk.”
Hanzhou, ZhejiangAges 18–70 - NCT05214547Recruiting
Focal vibration therapy for frozen shoulder pain and motion
This trial studies whether a vibration device applied to the shoulder can reduce pain and improve range of motion in people with frozen shoulder (also called adhesive capsulitis). If you fit the specific shoulder and symptom pattern, it may be an option to consider alongside standard care.
BitlisAges 18 years+ - NCT05222100Recruiting
Study how breast implants affect mammogram screening
This trial looks at whether having breast implants changes what happens during routine breast cancer screening with mammograms. It may help improve how screening is done and understood for people with implants.
GothenburgAges 40–75 - NCT05224297Recruiting
Help us improve radiation care by sharing your experiences
This study collects patient-reported experiences and side effects from people getting external beam radiation (radiation treatment from outside the body). Your answers can help doctors improve how radiation care is delivered and supported.
Vienna, State of ViennaAges 18–100 - NCT05224934Recruiting
Radiation before surgery for retroperitoneal soft-tissue sarcoma
This trial tests giving a shorter, lower-dose radiation treatment before surgery for a retroperitoneal (deep belly/back space) soft-tissue sarcoma. The goal is to shrink or control the tumor and make surgery more effective and safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05230758RecruitingPhase 3
Metformin trial for brain tumor survivors’ brain and behavior
This Phase 3 study tests whether metformin can improve brain function, behavior, and thinking in children and teens who were treated for certain brain tumors. You may be able to join if you meet age, time-since-treatment, language, and health/lab safety requirements.
New Lambton Heights, New South WalesAges 7–21 - NCT05231265Recruiting
Lumbar surgery effect on walking complexity in chronic low back pain
This study looks at how lumbar spine surgery (fusion or artificial disc “prosthesis” on one or two levels) affects how complex your walking looks and feels. It may help doctors better understand what to expect from surgery and how it changes movement in people with long-term low back pain.
NîmesAges 18 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,871 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.