Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,871 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05044273Recruiting
Study of two new stents and their safety in adults
This study checks how safe and effective two types of heart stents (Synergy XD and Synergy Megatron) are after they are placed. You might consider it if you’re an adult getting one of these stents and can follow required clinic visits.
AnyangAges 19 years+ - NCT05045066RecruitingEarly Phase 1
Vitamin D treatment study for Black men with prostate cancer
This early-phase study looks at how vitamin D replacement affects the immune system in Black/African American men with prostate cancer. It’s testing whether bringing vitamin D levels into a healthier range changes immune signals that may matter for cancer health.
Scottsdale, ArizonaAges 18 years+ - NCT05048680Recruiting
Breathing low-oxygen training to support brain blood flow in seniors
This study tests whether brief “low-oxygen” conditioning can improve blood flow to the brain and overall cerebrovascular (brain blood vessel) health in older adults. It may help people who are generally less active, as long as they have no major medical or safety barriers for the training.
La Tronche, Auvergne-Rhône-AlpesAges 60–80 - NCT05054257RecruitingPhase 1
CAR T19 for hard-to-treat blood cancers that have CD19
This Phase 1 study tests CAR T cells designed to attack cancer cells that carry a marker called CD19. It’s for adults with certain relapsed or treatment-resistant B-cell leukemias (ALL) or lymphomas (NHL) where other treatments may not have worked.
PragueAges 18–80 - NCT05055648RecruitingPhase 3
Proton vs photon radiation for esophageal cancer before surgery
This trial compares proton therapy and standard photon therapy given before surgery for esophageal (or stomach–esophagus) cancer. It aims to see which radiation approach works better and is safer as part of a combined treatment plan.
LeuvenAges 18 years+ - NCT05059379RecruitingPhase 3
Different radiation fields after breast cancer surgery
This trial compares two ways of giving radiation to lymph node areas near the collarbone after surgery for invasive breast cancer. It aims to see which radiation approach works better and is safer for preventing cancer returning in these lymph nodes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05075005Recruiting
Study tests foot muscle effects of different walking surfaces
This study compares how different walking surfaces affect foot muscle activity in people with plantar fasciitis and in healthy adults. It’s aimed at better understanding what changes happen in the foot and how terrain might influence symptoms and muscle function.
Gainesville, FloridaAges 18–100 - NCT05078671RecruitingPhase 4
Testing a drug-boost to improve olaparib levels and side effects
This Phase 4 study tests whether adding a “booster” medicine can raise olaparib levels in the body so it may be better tolerated and more cost-effective. You may be eligible if you are already taking olaparib and meet health and medication safety requirements.
's-HertogenboschAges 18 years+ - NCT05087667Recruiting
Polymer wiring for arm or thigh fractures: tested vs standard care
This trial compares a new type of polymer cerclage (a strong wire used to support a fracture) against standard cerclage wiring used in routine care. It may help doctors learn which option works better for healing in certain arm (humerus) or thigh (femur) fractures.
Agen, FranceAges 18 years+ - NCT05095740Recruiting
Testing brain stimulation for laryngeal dystonia symptoms
This study tests whether a noninvasive brain stimulation treatment (referred to as neuromodulation, such as rTMS) can improve symptoms of laryngeal dystonia. It’s meant to see if stimulating certain brain areas can reduce how severely your voice/throat problem affects you.
Boston, MassachusettsAges 21–85 - NCT05094297Recruiting
Study of muscle contraction training for veteran tiredness and pain
This study tests whether a guided exercise approach using focused muscle contractions can improve pain, fatigue, or low energy in U.S. Veterans. If you’re having trouble doing everyday activities, this program may help you feel better and function more easily.
Chicago, IllinoisAges 18 years+ - NCT05095909Recruiting
Frozen compression at intervals vs regular icing after shoulder surgery
This trial tests whether using a special device that gives cold in pulses (intermittent cryo-compression) helps the shoulder feel better after arthroscopic rotator cuff repair compared with traditional icing. It may help with pain and recovery during the early healing period after surgery.
Plymouth, MinnesotaAges 18–70 - NCT05100381Recruiting
Dry needling for long-lasting lower back muscle pain
This study tests whether dry needling (thin needles placed into specific muscles) can reduce moderate, long-lasting lower back pain. It focuses on people who have pain from trigger points in a specific back muscle, rather than pain caused by other medical problems.
Tehran, Tehran ProvinceAges 18–45 - NCT05102968Recruiting
App-based home rehab after shoulder arthroscopy
This study tests whether using a communication app to help you do home rehabilitation after arthroscopic shoulder surgery improves recovery and function. If you have a small to medium full-thickness rotator cuff tear (or certain subscapularis tears) and can commit to follow-up for two years, you may be eligible.
Kaohsiung CityAges 20–70 - NCT05107908Recruiting
Test brain and behavior effects of a hidden message on eating
This study tests whether a subtle “priming” approach can improve eating behaviors in people with obesity. It also looks at brain activity during the process to understand how the approach may work.
Aurora, ColoradoAges 18–65 - NCT05112328Recruiting
Pancreatic enzyme added to feeding for ICU adults
This study tests whether adding pancreatic digestive enzymes to tube feeding can improve digestion and outcomes in critically ill adults who have higher risk of not producing enough digestive enzymes. If you qualify, you may receive the enzyme supplement or a comparison treatment while you’re in the ICU.
Seoul, Jongno-guAges 18 years+ - NCT05115929Recruiting
Surgery for dangerously high pressure after head injury
This trial compares two emergency surgery approaches for people with traumatic brain injury who have dangerously high pressure inside the skull that does not improve with standard treatments. The goal is to see which approach leads to better long-term outcomes.
ClamartAges 18–65 - NCT05123625Recruiting
Testing lymph node removal during bladder cancer surgery
This study looks at whether removing nearby lymph nodes during radical cystectomy (bladder removal) improves outcomes for people with high-risk non–muscle-invasive bladder cancer. It may help doctors choose the best surgical approach to reduce the chance of cancer coming back.
Nanjing, JiangsuAges 18–75 - NCT05125146Recruiting
Internet CBT for insomnia versus medicines
This study compares an online form of CBT (a structured therapy for sleep) with sleep medicines for adults with insomnia. It may help you see which approach improves how easily you fall asleep and stay asleep.
Kingston, OntarioAges 18 years+ - NCT05137119RecruitingPhase 4
Adaptive study of treatments for staph bloodstream infection
This trial tests the best treatment approach for bloodstream infections caused by Staphylococcus aureus (“S. aureus”). It uses a flexible design to decide which treatment track you fit into, and may help improve recovery while avoiding unnecessary medications.
Houston, TexasAges Any age - NCT05142683Recruiting
Test an integrated care plan for teens with depression
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
Toronto, OntarioAges 13–18 - NCT05142735Recruiting
NAC for early psychosis risk symptoms
This trial studies whether NAC (a nutrient-like supplement) can reduce symptoms in people who are at high risk for developing psychosis. It may help by testing a safer, non-standard treatment approach for early warning signs.
Toronto, OntarioAges 16–35 - NCT05150795RecruitingEarly Phase 1
Testing pregabalin before surgery versus fentanyl during surgery
This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.
CairoAges 21–45
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,871 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.