Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07088055Recruiting
Chewing device vs. oral motor therapy for jaw alignment in kids
This study tests whether a special chewing device (Myo Munchee) can help improve jaw alignment and muscle function in children ages 3–5 who have both jaw alignment problems and orofacial myofunctional disorders. It compares the device to standard oral motor therapy.
Chicago, IllinoisAges 3–5 - NCT07094516RecruitingPhase 2
Testing VHB937 for early Alzheimer's disease
This trial tests a new medicine, VHB937, in people with early Alzheimer's (mild cognitive impairment or mild dementia). The goal is to see if it can slow down memory loss and thinking problems.
Phoenix, ArizonaAges 50–85 - NCT07089238Recruiting
Citicoline for mood in healthy adults
This study tests whether a supplement called citicoline can improve mood in healthy adults who have some mild mood disturbance. It is designed to see if taking citicoline leads to a better mood.
Canfield, OhioAges 21–65 - NCT07092605Enrolling by invitationEarly Phase 1
Microdosed semaglutide for longer, healthier life
This trial tests whether a very low ('micro') dose of semaglutide can improve health, quality of life, and how long you live well. It's for people who are interested in the drug's general health benefits but not specifically for weight loss.
Ann Arbor, MichiganAges 18–65 - NCT07090876Recruiting
Grape seed extract for blood pressure
This trial tests whether a grape seed extract supplement can help people with slightly high blood pressure (called high-normal) improve their heart health. It may be an option if your blood pressure is borderline and you are not taking blood pressure medications.
Bologna, BoAges 18–70 - NCT06706752Recruiting
Shengbai oral formula for chemotherapy side effects
This study tests if a Chinese herbal formula called Shengbai can safely reduce side effects from chemotherapy. It might help you feel better during cancer treatment.
Oakland, CaliforniaAges 18–80 - NCT06750302RecruitingPhase 1/Phase 2
Penthrox vs placebo for sinus surgery pain
This trial tests if a pain reliever called Penthrox (methoxyflurane) works better than a placebo for pain during minor sinus procedures. If you are having a simple sinus surgery or coblation procedure, you may be able to join.
Vancouver, British ColumbiaAges 19 years+ - NCT07090928RecruitingPhase 4
Numbing medicine for less pain after knee scope surgery
This study tests whether giving bupivacaine (a numbing medicine) around the time of knee arthroscopy can reduce pain at the surgery sites and help you move your knee better after the operation.
Peshawar, KPKAges 18–70 - NCT07092930RecruitingPhase 3
Supplements for athletic performance and health
This trial tests if beta-alanine and sodium bicarbonate supplements can improve your physical performance and certain health markers. If you are a healthy, experienced athlete, this study might help you understand how these supplements affect your body.
Poznan, WielkopolskaAges 16–40 - NCT07085806Recruiting
Pentoxifylline for liver growth after donor surgery
This study tests if a medicine called pentoxifylline can help your liver grow faster after donating a large part of it. You would take the medicine before and after your donor surgery.
New DelhiAges 18–55 - NCT07087093Recruiting
Ketone drink effects on aging immune cells in healthy older adults
This study tests whether a special drink called a ketone ester can reduce inflammation and improve immune cell health in healthy older adults. It aims to see if this drink helps aging immune cells (T cells) work better.
Harbin, HeilongjiangAges 65–80 - NCT07093489Recruiting
LC16m8 mpox vaccine study in the DRC
This study tests whether a single dose of the LC16m8 mpox vaccine is safe and works in people living in the Democratic Republic of Congo. It also monitors for side effects and tracks mpox cases to see how well the vaccine protects the community.
KinshasaAges 1 year+ - NCT07095205RecruitingPhase 4
Nicotine's effect on depression in brain imaging study
This trial uses a special brain scan to see how nicotine might help treat depression. It compares people with depression to healthy volunteers to understand how nicotine affects brain chemistry related to mood.
Stony Brook, New YorkAges 18–65 - NCT07088900Recruiting
Dexmedetomidine with bupivacaine for pain relief in children's appendix surgery
This trial tests if adding dexmedetomidine to bupivacaine (a numbing medicine given near the tailbone) provides better pain relief during and after appendix surgery in children. It may help reduce the need for other pain medicines.
CairoAges 2–7 - NCT07090057Recruiting
Targeting the plantaris muscle in ankle surgery for children
This study tests if removing the plantaris muscle during surgery improves ankle movement in children with tight heel cords. It aims to see if this extra step leads to better outcomes.
Edmonton, AlbertaAges 4–17 - NCT07088172Recruiting
Gum graft timing for dental implants in the lower back jaw
This trial compares two different times to do a gum graft around a dental implant in the lower back jaw. It aims to find out which timing works better for patients who don't have enough thick gum tissue (less than 2 mm).
Hangzhou, ZhejiangAges 18 years+ - NCT07089173Recruiting
Testing lidocaine or sufentanil to ease breathing tube placement
This trial tests whether adding lidocaine or sufentanil to a standard anesthetic drug (etomidate) helps reduce the dose of remifentanil needed to place a breathing tube comfortably. It may help patients undergoing planned surgery with general anesthesia.
Shenzhen, GuangdongAges 18–65 - NCT07092527RecruitingPhase 4
Testosterone's effects on hormones in transgender and cisgender people
This study looks at how testosterone affects the brain and reproductive hormones in people who are starting testosterone therapy and those who are not. It aims to understand the body's natural hormone cycles.
San Diego, CaliforniaAges 18–35 - NCT07087236Enrolling by invitation
How sitting and light activity affect your brain
This study looks at how different levels of sitting and light activity—from being still to moving a bit—affect your thinking and brain state. It includes both children and adults, with or without health conditions like obesity.
Viña del MarAges 5 years+ - NCT07093060RecruitingEarly Phase 1
Oxytocin and atosiban effects on social attention
This trial tests how two oral medications, oxytocin and atosiban, affect the way healthy men pay attention to social cues. It aims to understand how these drugs influence social brain function.
Chengdu, SichuanAges 18–35 - NCT07090837Recruiting
Support study for caregivers of older adults
This study tests whether using a mobile app can help support caregivers of older adults receiving home-based care. It aims to see if this improves caregiver well-being.
SingaporeAges Any age - NCT07094581Recruiting
How adenoid size affects chewing muscle in children
This study uses ultrasound to see if enlarged adenoids affect the masseter muscle (a chewing muscle) in children. It may help doctors understand how breathing problems during sleep or mouth breathing impact jaw muscles.
Aydin, EfelerAges 3–8 - NCT07090551Recruiting
Mouthguard for jaw and neck muscle pain from grinding
This study tests whether a custom mouthguard (occlusal splint) can reduce pain and tension in the jaw and neck muscles. It is for people with bruxism (teeth grinding) and myofascial pain, a type of muscle pain in the jaw area.
IstanbulAges 18–50 - NCT07090772Enrolling by invitation
Comparing jaw position methods for splint therapy in TMJ disc displacement
This trial tests different ways to determine the best jaw position for a mouth splint used to treat a specific type of temporomandibular joint (TMJ) problem where the disc is out of place and doesn't go back. The goal is to see which method works better for reducing pain and improving jaw function.
Fuzhou, FujianAges 13–50
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.