Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03821857RecruitingPhase 4
Study of hormone disruption effects on aging and Alzheimer’s
This trial studies how hormone (endocrine) disruption may affect aging and Alzheimer’s disease in women. It may help researchers understand why these effects can differ by sex and how to better assess or track risk over time.
Jacksonville, FloridaAges 60 years+ - NCT04855825Recruiting
Wearable robotic exoskeleton to improve walking and thinking in MS
This study tests a wearable robotic exoskeleton to help people with multiple sclerosis walk better and improve thinking/problem-solving. You would use the device during supervised sessions and take brief thinking and movement checks to see if it’s safe and helpful for you.
West Orange, New JerseyAges 18–75 - NCT05864274Recruiting
Cognitive training for people on chemotherapy
This trial studies a phone or tablet brain-training program to help with “cancer-related cognitive impairment,” or thinking and memory problems that can happen during chemotherapy. If you’re newly diagnosed with certain gynecologic cancers and are receiving chemotherapy, this may help you see whether the training improves cognitive symptoms.
Birmingham, AlabamaAges 18–90 - NCT05886036RecruitingPhase 2
Comparing rituximab vs mosunetuzumab for NLPHL
This trial compares two immunotherapy drugs, rituximab and mosunetuzumab, to see which works better for people with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) who need treatment. It's for both newly diagnosed and previously treated patients.
Duarte, CaliforniaAges 18 years+ - NCT05880719Recruiting
Music-based computer program for memory after first psychosis
This study tests whether using a computer-based music program can help improve memory and thinking in young people who have had their first episode of psychosis. Participants will work in small groups with the program to see if it helps their cognitive skills.
CaenAges 18–30 - NCT05885048Recruiting
Testing how cancer treatments affect future fertility
This study looks at how treatments that can harm ovaries or testicles (like certain chemotherapy, radiation, and immune therapies) may affect fertility. It may help you and others by measuring hormone levels (and in some cases sperm) before and during/after treatment.
BernAges 14–50 - NCT05899933Recruiting
Compare two surgical treatments for peri-implantitis
This study compares two different surgical approaches to treat peri-implantitis, an infection/inflammation around dental implants. You may be enrolled because you have a qualifying implant and meet health and medication requirements.
AthensAges 18–80 - NCT05907265Recruiting
Virtual reality sessions to improve thinking after chemotherapy
This study tests whether immersive virtual reality training can improve thinking and concentration in adults who have had ongoing thinking problems after chemotherapy. It may help by using guided VR tasks that aim to support cognitive skills during recovery.
TerrassaAges 18–65 - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85 - NCT05884138Recruiting
Amino acid supplement and exercise for people on dialysis
This trial studies whether taking essential amino acids along with exercise can improve muscle function in people receiving hemodialysis. It may help you build or maintain strength and mobility.
Daejeon, South KoreaAges 20–80 - NCT05906238Recruiting
Study to reduce harm from obesity stigma
This trial looks at ways to lessen the negative effects that people may experience from weight-related stigma. It’s meant to help improve well-being for people living with obesity.
Poitiers, VienneAges 18 years+ - NCT05907239Recruiting
Shock wave therapy for jaw muscle pain
This trial tests whether focused shock wave treatment can reduce chronic jaw pain caused by jaw muscle problems. You might qualify if you have moderate to severe temporomandibular (jaw) pain for at least 3 months.
São Paulo, São PauloAges 18 years+ - NCT05882708RecruitingPhase 4
Ivabradine to slow heart rate in sepsis ICU patients
This study tests whether ivabradine (a heart-rate medicine) can improve blood flow and other vital measurements in adults with sepsis in the ICU. It may help by lowering a fast heart rate when blood pressure is already being supported.
Guangzhou, GuangdongAges 18 years+ - NCT05903027Recruiting
Testing gepant migraine treatment for better side effects
This trial studies how well a “gepant” medicine works for different types of migraine and how tolerable it is. It may help if you have frequent migraines and you can keep a headache diary as the study asks.
FlorenceAges 18 years+ - NCT05894265Recruiting
Test collagen patch versus standard care after rotator cuff repair
This study compares a collagen “patch” placed during arthroscopic rotator cuff surgery versus the usual standard repair. It looks at safety and whether the patch improves healing and shoulder function after surgery.
Houston, TexasAges 18–80 - NCT05885061Recruiting
Spinal cord stimulation study for adults with chronic pain
This study looks at how spinal cord stimulation affects chronic pain in adults who already have the device implanted. It may help researchers understand who benefits most and how stable pain and treatments need to be to measure results.
AarhusAges 18–99 - NCT05890612Recruiting
Study of Paxlovid safety and effectiveness in high-risk COVID-19
This study observes people at higher risk for severe COVID-19 who take Paxlovid, to better understand how well it works and how safe it is in real-world use. It may help doctors confirm the best way to use Paxlovid and spot any side effects.
SeoulAges 19 years+ - NCT05875870Recruiting
Bright light and exercise program for lung or esophageal cancer
This trial tests whether a structured bright-light exposure routine combined with a specific exercise program can help people with newly diagnosed lung or esophageal cancer. You may be eligible if you’re in early-to-middle cancer stages and able to safely participate in walking-based activities.
Taipei City, TaipeiAges 20 years+ - NCT05861986RecruitingPhase 4
Risdiplam for very young children after gene therapy for SMA
This trial studies whether risdiplam, given early after gene therapy, is safe and helps children with spinal muscular atrophy (SMA) keep improving or stay stable. It focuses on children under 2 years old who already received gene therapy and need to meet timing and health requirements.
Little Rock, ArkansasAges 3 months–2 years - NCT05868408Recruiting
Whey formula for healthy full-term infants – growth and comfort
This study tests whether a special partially-digested whey formula is as good as standard formula for healthy full-term babies. It looks at how babies grow and how well they tolerate the formula.
Cavite CityAges birth–4 weeks - NCT05861999RecruitingPhase 4
Risdiplam for young children with SMA after gene therapy plateau
This trial studies whether risdiplam is safe and helpful for children under 2 with spinal muscular atrophy (SMA) whose function has leveled off or declined after gene therapy. It may be an option if you saw benefits from gene therapy but then noticed a stop or setback in key abilities.
Little Rock, ArkansasAges 3 months–2 years - NCT05856136RecruitingPhase 4
Study how opioid exposure affects diaphragm muscle function
This study looks at whether receiving opioids for pain during lower-leg surgery changes how well the diaphragm muscle (the main breathing muscle) works afterward. It compares breathing muscle function in people who do and do not have certain lung conditions.
Rochester, MinnesotaAges 18 years+ - NCT05851859Recruiting
Breathing training for long COVID symptoms
This study tests whether a structured breathing control technique can improve symptoms of long COVID. It may help by training how you breathe, but you must meet specific health and medication criteria to join.
Saint-DenisAges 18 years+ - NCT05858411Recruiting
Biologic gum treatments added to non-surgical cleaning
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
TiranaAges 18 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.