Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07738952RecruitingPhase 1/Phase 2
Sivelestat for neuromyelitis optica spectrum disorder relapses
This study tests a drug called sivelestat for people with neuromyelitis optica spectrum disorder (NMOSD) who are having a relapse. The drug may help reduce damage during the relapse and improve recovery.
FukuokaAges 18 years+ - NCT05799326Recruiting
Levofloxacin after sudden stroke to improve safety and recovery
This trial tests whether the antibiotic levofloxacin can be given soon after an acute ischemic stroke to improve outcomes and monitor side effects. It’s for people with a moderate stroke severity who are not having certain emergency treatments or infections.
Changchun, JilinAges 18–75 - NCT07734844RecruitingPhase 3
New vs existing treatment for diabetic macular edema
This study compares a new medication, tabirafusp tedromer, to an existing treatment, aflibercept, for people with diabetic macular edema (swelling in the back of the eye from diabetes). It may help if your DME hasn't improved or you're looking for a new option.
Glendale, CaliforniaAges 18 years+ - NCT07734415Enrolling by invitationPhase 2
Long-term safety of IMG-007 for moderate-to-severe eczema
This study checks the long-term safety and effectiveness of IMG-007 in people with moderate-to-severe atopic dermatitis (eczema) who have already finished a previous IMG-007 trial.
Lancaster, CaliforniaAges 18–75 - NCT07728539Recruiting
Comparing a faster ablation method for atrial fibrillation
This study compares a newer, faster type of ablation (high-power short-duration) with the standard approach for treating atrial fibrillation. The goal is to see which method is safer and more effective at restoring a normal heart rhythm.
MoscowAges 18–70 - NCT07723963RecruitingPhase 2/Phase 3
Study of JZP926 for juvenile myoclonic epilepsy
This study tests an investigational drug called JZP926 (a type of cannabinoid) to see if it can reduce the number of days with myoclonic seizures in people with juvenile myoclonic epilepsy. If you have this condition and are at least 10 years old, you might be able to join.
Phoenix, ArizonaAges 10 years+ - NCT07725939RecruitingPhase 2
Study of Galvokimig for moderate-to-severe COPD with chronic bronchitis
This study tests an experimental drug called Galvokimig (taken as a pill) to see if it can reduce COPD flare-ups and improve lung function in people with moderate to severe COPD and chronic bronchitis. It is for those who have had recent flare-ups and are already using maintenance inhalers.
Miami, FloridaAges 40–80 - NCT07732023RecruitingPhase 1
Study of a new asthma medication compared to placebo
This study tests an investigational medication (SKB575) for people with asthma. It aims to see if the drug is safe and works better than a placebo when added to your regular asthma treatments.
Chengdu, SichuanAges 18–70 - NCT07725822RecruitingPhase 4
Cream for psoriasis affecting skin and nails
This study tests a new prescription cream called roflumilast to see if it helps with both skin plaques and nail psoriasis. If you join, you'll apply the cream to affected areas and be monitored to see how well it works and if it's safe.
Dallas, TexasAges Any age - NCT07728292Recruiting
Underwater removal of small gastric neuroendocrine tumors
This trial tests a special underwater technique to remove small type I gastric neuroendocrine tumors (5-9 mm) during an endoscopy. The goal is to see if it is safe and effective, which could offer a less invasive treatment option.
Hyderabad, TelanganaAges 18–65 - NCT07728019RecruitingPhase 2
New drug combo for untreated colon cancer with liver spread
This trial tests a new combination of drugs (Retlirafusp Alfa, Bevacizumab, and chemotherapy) with or without a short course of radiation for people with colorectal cancer that has spread only to the liver and who have not had any prior treatment. The goal is to see if this approach is safe and effective.
Wuhan, HubeiAges 18–75 - NCT07726888Recruiting
Guselkumab for moderate-to-severe ulcerative colitis
This study tests a drug called Guselkumab (already approved for other conditions) for treating moderate to severe ulcerative colitis. It aims to see how safe and effective the drug is in real-world patients who have not had success with other treatments.
Wenzhou, ZhejiangAges 18 years+ - NCT07724899Recruiting
A new ablation treatment for atrial fibrillation
This study tests a new type of ablation (pulsed field ablation) for people with atrial fibrillation who haven't gotten enough relief from medication alone. It aims to see if isolating the superior vena cava along with the pulmonary veins is safe and effective.
Chengdu, SichuanAges 18 years+ - NCT06607731Recruiting
Alcohol gel treatment for aggressive angiomas
This trial studies a treatment using a special gelled alcohol to shrink aggressive angiomas (abnormal blood vessel growths). It aims to see if the procedure is safe, feasible, and works well.
Saint-Priest-en-JarezAges 18 years+ - NCT07717346RecruitingEarly Phase 1
KB111 topical gel for Hailey-Hailey disease
This trial tests a new topical gel called KB111 for treating Hailey-Hailey disease, a genetic skin condition that causes painful blisters. The study will check if the gel is safe and helps reduce symptoms.
Miami, FloridaAges 12 years+ - NCT07720882Recruiting
Brain implant study to restore hand function after spinal cord injury
This trial tests a fully implanted wireless brain-computer interface (BCI) to help people with paralysis from a neck-level spinal cord injury regain hand and arm movement. The BCI reads brain signals and sends them to your arm, bypassing the damaged spinal cord.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07720375RecruitingPhase 2
Study of galvokimig for non-cystic fibrosis bronchiectasis
This study tests a new medicine called galvokimig for adults with non-cystic fibrosis bronchiectasis, a condition where airways are damaged and cause chronic cough and sputum. The goal is to see if it reduces flare-ups and improves lung health.
Brandon, FloridaAges 18–80 - NCT07720284RecruitingPhase 3
Testing new drugs for high-risk bladder cancer after surgery
This trial tests a new combination of drugs (Dato-DXd plus rilvegostomig) against standard treatments for people with high-risk, muscle-invasive bladder cancer that has been surgically removed. The goal is to see if the new treatment reduces the chance of the cancer coming back.
Hot Springs, ArkansasAges 18 years+ - NCT06636552RecruitingPhase 2
Alternating drug combo plus daratumumab for newly diagnosed plasma cell leukemia
This trial tests a new treatment plan for people newly diagnosed with primary plasma cell leukemia (pPCL). It uses two different drug combinations that include daratumumab, given one after the other, followed by maintenance daratumumab. The goal is to see if this approach is safe and works well.
Athens, AtticaAges 18–80 - NCT07723261Recruiting
Testing NalIriFOx as first treatment for metastatic pancreatic cancer
This trial is testing a drug combination called NalIriFOx as the first treatment for people with pancreatic cancer that has spread. The goal is to see if it is safe and works well over the long term.
AthensAges 18 years+ - NCT06635330RecruitingPhase 1/Phase 2
CAR T cell therapy for children with relapsed B-cell leukemia
This trial tests a new CAR T cell treatment for children whose B-cell acute lymphoblastic leukemia has come back or not responded to standard therapy. The goal is to see if this therapy is safe and can help control the cancer so a stem cell transplant may be possible.
Tehran, Tehran ProvinceAges 2–18 - NCT06601179Recruiting
HIFU ultrasound for enlarged prostate
This trial tests a focused ultrasound treatment for benign prostatic hyperplasia (BPH), which is a non-cancerous enlargement of the prostate. It aims to see if HIFU can safely relieve symptoms like weak urine flow and frequent urination.
BesançonAges 50–85 - NCT06607770RecruitingPhase 1/Phase 2
Cryoablation with immunotherapy for multiple lung cancers
This trial tests freezing tumors (cryoablation) combined with two drugs (Karelizumab and Apatinib) for people who have several small lung cancer spots in their lungs but no spread to lymph nodes. The goal is to see if this combination is safe and helps shrink or control the tumors.
Guangzhou, GuangdongAges 18–75 - NCT07712523RecruitingPhase 2
Testing QY201 tablets for non-segmental vitiligo
This trial tests an experimental oral tablet called QY201 to see if it can improve vitiligo (white patches on the skin). It is for adults with non-segmental vitiligo, regardless of whether the patches are currently growing or stable.
Shenyang, LiaoningAges 18–65
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.