Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,824 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07458256Recruiting
Liposomal bupivacaine for pain after laparoscopic surgery
This trial tests a long-acting painkiller injected during surgery to see if it reduces pain after keyhole (laparoscopic) procedures like gallbladder removal, hernia repair, or appendix removal. It may help you need fewer opioids and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–64 - NCT07616453RecruitingPhase 2
New Drug Plus Hormone Therapy for Hormone-Responsive Breast Cancer
This trial tests whether a new drug called culmerciclib, combined with hormone therapy, works better than hormone therapy alone for early-stage breast cancer that grows quickly and responds to estrogen. The goal is to shrink tumors before surgery and improve outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT07066527Recruiting
New foam vs. standard foam for head and neck vein malformations
This study tests a new type of foam (polylauric alcohol foam) compared to standard foam for treating venous malformations (clusters of abnormal veins) in the head and neck area. The goal is to see if the new foam works better and is just as safe.
Jinan, ShandongAges 14–60 - NCT02852213RecruitingPhase 1
Dose-check study for children with AADC deficiency using brain surgery
This Phase 1 trial tests how safe different treatment doses are for children with AADC deficiency, using MRI-guided brain surgery. It may help improve movement and developmental progress after standard medicines did not work well enough.
San Francisco, CaliforniaAges 2 years+ - NCT06928090Enrolling by invitation
HIV trial testing two-med combo for first-time treatment
This trial studies a two-drug pill (DTG/3TC) for people who have never taken HIV medication before. It aims to see if this simpler treatment is effective and safe for controlling HIV-1.
DaejeonAges 19 years+ - NCT07409103RecruitingPhase 2
Testing ELV001 for active rheumatoid arthritis
This study tests a new medication, ELV001, for people with active rheumatoid arthritis who haven't improved enough with methotrexate and a TNF inhibitor. The goal is to see if different doses of ELV001 are safe and can help reduce joint pain and swelling.
Gilbert, ArizonaAges 18–75 - NCT06927310RecruitingPhase 3
Growth Hormone Injection for Idiopathic Short Stature in Children
This study tests a new growth hormone injection (Inpegsomatropin) to help children with idiopathic short stature (short stature with no known cause) grow taller. It may be an option if your child is very short compared to peers and has not started puberty.
Hefei, AnhuiAges 3–11 - NCT06081907RecruitingPhase 1/Phase 2
IBI363 for advanced solid tumors
This trial tests a new drug called IBI363 for people with advanced solid tumors, focusing on lung cancer and melanoma. It aims to see if the drug is safe and effective, especially for those whose previous treatments have stopped working.
Changsha, HunanAges 18–75 - NCT07286032RecruitingPhase 3
Study of a pill to raise low platelets after chemo
This study tests an investigational pill (hetrombopag) to see if it can safely raise platelet counts in people with solid tumors whose platelets drop after chemotherapy. If you are receiving platinum- or gemcitabine-based chemo and have low platelets due to chemo, this trial may be an option.
Los Alamitos, CaliforniaAges 18 years+ - NCT03689842Recruiting
Testing living-donor uterine transplant for MRKH
This study tests whether transplanting a uterus from a living related donor can be done safely and can help patients with MRKH type I achieve pregnancy. It also checks risks and safety issues for both the donor and recipient.
SuresnesAges 18–65 - NCT07042516RecruitingPhase 2
Asimadoline for hot flashes in women going through menopause
This study tests if asimadoline can safely reduce hot flashes and night sweats in menopausal or late perimenopausal women. You must not be on any medications for hot flashes currently.
Atlanta, GeorgiaAges 40–62 - NCT07493824RecruitingPhase 4
Study of Paiteling Antibacterial Liquid for Persistent HPV Infection
This trial tests an antibacterial liquid (Paiteling®) to see if it can clear a persistent high-risk HPV infection of the cervix. It may be an option for women whose HPV has lasted 2 years or more and whose cervical biopsy shows only mild changes.
Changchun, JilinAges 26–65 - NCT07614191RecruitingEarly Phase 1
GT801 Cell Therapy for Hard-to-Treat Autoimmune Diseases
This early-stage study tests a new cell-based treatment called GT801 for autoimmune diseases that haven't responded well to standard medicines. It aims to see if this approach is safe and helps reduce symptoms in conditions like lupus, vasculitis, and scleroderma.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07263386RecruitingPhase 2
Immunotherapy plus chemo for PD-L1-positive stomach cancer
This trial tests whether adding the immunotherapy drug sintilimab to standard chemotherapy (SOX) after surgery helps prevent stomach cancer from returning. It’s for people whose tumors have a protein called PD-L1 and who had cancer in at least 7 lymph nodes.
Nanjing, JiangsuAges 18–75 - NCT06660992RecruitingPhase 3
Study of HSK31858 for non-CF bronchiectasis
This trial tests a new medicine, HSK31858, for people with non-cystic fibrosis bronchiectasis (a lung condition causing chronic cough and infections). It aims to see if the drug reduces lung flare-ups and improves symptoms.
Guangzhou, GuangdongAges 18 years+ - NCT07381829RecruitingPhase 1
HC010 plus chemotherapy for advanced lung cancer
This trial tests an experimental drug called HC010 combined with chemotherapy for people with advanced lung cancer, including certain types of non-small cell or small cell lung cancer. It aims to see if the combination is safe and effective.
Guangzhou, GuangdongAges 18–75 - NCT06690333Recruiting
Comparing leadless pacemakers to left bundle area pacing
This study compares two types of pacemakers: a small leadless pacemaker (placed directly in the heart without wires) and a newer pacing technique called left bundle area pacing. It aims to see which is safer and works better for people who need a pacemaker due to heart block or after a TAVR procedure.
Naples, FloridaAges 18 years+ - NCT06930118RecruitingPhase 2
Study of 4 drugs for advanced colorectal cancer
This trial tests a combination of four drugs for people with advanced colorectal cancer who have already tried at least two other treatments. The goal is to see if this new mix can help shrink tumors or slow the cancer's growth.
ShanghaiAges 18 years+ - NCT07066540Recruiting
Trial of Reamberin for Viral Stomach Infections in Children
This trial tests if the drug Reamberin, given through an IV, can help children aged 1 to 6 recover faster from a viral stomach infection. It's for kids who need fluids through a vein and have symptoms like vomiting, fever, and tiredness.
ChelyabinskAges 1–6 - NCT07237230Recruiting
Gamma-delta T cells to prevent leukemia relapse after transplant
This trial tests if a special type of immune cell called gamma-delta T cells can help prevent acute myeloid leukemia from coming back after a stem cell transplant. It is for people with high-risk features who have recently had a transplant.
Wuhan, HubeiAges 18–65 - NCT05015283Recruiting
Gastric bypass type surgery to help type 2 diabetes go into remission
This study compares two kinds of weight-loss surgeries to see which helps people with type 2 diabetes reach diabetes remission more safely. It may help if your diabetes is not well controlled and your care team recommends one of these operations.
Beijing, Beijing MunicipalityAges 18–65 - NCT07695207RecruitingPhase 3
Testing SMZ1 with ranibizumab for wet macular degeneration
This trial tests a new medicine called SMZ1 combined with ranibizumab (a standard treatment) for people with wet macular degeneration. It may help improve vision by targeting the cause of the disease more effectively.
Seoul, SeoulAges 50 years+ - NCT05226169RecruitingPhase 3
Iron medicine plus standard therapy for advanced stomach cancer
This Phase 3 study tests whether giving ferric carboxymaltose (an IV iron treatment) helps people with advanced stomach or stomach–esophagus cancer and iron-deficiency anemia. The goal is to improve safety and how well the standard first-line cancer treatment works.
SeoulAges 19 years+ - NCT06351150RecruitingPhase 3
Testing angiotensin II for refractory distributive shock
This study tests an injection of angiotensin II (a substance that helps tighten blood vessels) versus a placebo for patients with distributive shock that is not responding to standard treatments. It may help raise blood pressure and improve outcomes.
Hefei, AnhuiAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,824 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.