Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07711223RecruitingPhase 1/Phase 2
New HIV pill compared to standard treatment for untreated adults
This trial compares a new HIV medication (ACC017) to an existing one (dolutegravir) in adults who have HIV but have never taken HIV drugs before. The goal is to see if the new pill works as well and is safe.
BeijingAges 18 years+ - NCT07712523RecruitingPhase 2
Testing QY201 tablets for non-segmental vitiligo
This trial tests an experimental oral tablet called QY201 to see if it can improve vitiligo (white patches on the skin). It is for adults with non-segmental vitiligo, regardless of whether the patches are currently growing or stable.
Shenyang, LiaoningAges 18–65 - NCT07709598RecruitingPhase 2/Phase 3
HL-1186 for pain after abdominal surgery
This study tests a new painkiller called HL-1186 for people having abdominal surgery. If you qualify and enroll, you will receive the drug after surgery to see if it safely helps reduce your pain better than a placebo (a pill with no medicine).
Chengdu, SichuanAges 18–75 - NCT07706985RecruitingPhase 3
Immunotherapy for advanced nasopharyngeal cancer
This trial tests a new combination of chemotherapy and immunotherapy drugs for advanced nasopharyngeal cancer that has not spread to distant parts of the body. The goal is to see if this approach works better than standard treatment.
Guangzhou, GuangdongAges 18–70 - NCT07711171RecruitingPhase 4
Canagliflozin for type 2 diabetes with mild memory problems
This trial tests whether the diabetes drug canagliflozin can help people with type 2 diabetes and mild cognitive impairment. It may slow down memory and thinking problems while also improving blood sugar control.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT07710157RecruitingPhase 2
Obinutuzumab for first episode of minimal change disease
This trial tests if obinutuzumab, a targeted therapy, can safely and effectively treat adults with their first episode of minimal change disease (MCD), a kidney condition causing protein leakage. Participants will receive the drug to see if it reduces protein in urine and improves symptoms.
GrazAges 18 years+ - NCT07707687RecruitingPhase 2
Eculizumab for high-risk TA-TMA after stem cell transplant
This trial tests whether eculizumab can safely help people with a serious blood vessel complication called TA-TMA after a stem cell transplant. You may be eligible if you have high-risk features and haven't improved with initial care.
Changsha, HunanAges 18 years+ - NCT06641544RecruitingPhase 4
Testing different drug combos for HER2-positive breast cancer
This trial tests different combinations of the drug Inetetamab as a first treatment for breast cancer that has spread and is HER2-positive. It aims to find which combo works best and is safe for newly diagnosed metastatic patients.
Shanwei, GuangdongAges 18–70 - NCT04981145RecruitingPhase 4
Iguratimod for Sjögren’s syndrome symptoms and safety
This trial studies whether iguratimod improves symptoms in people with primary Sjögren’s syndrome, and checks how safe it is. It focuses on people with confirmed disease markers (anti-SSA/Ro-60) and ongoing dry eyes and dry mouth.
Hangzhou, ZhejiangAges 18–70 - NCT04547166RecruitingPhase 2/Phase 3
New targeted immune drug plus bevacizumab and chemo for colon cancer
This trial studies serplulimab (an immune-related drug) together with bevacizumab and chemotherapy to treat metastatic colorectal (colon) cancer that cannot be removed with surgery. It aims to see whether this combination improves outcomes and is safe.
Guangzhou, GuangdongAges 18–75 - NCT06498089RecruitingPhase 4
Comparing tailored vs. standard treatment for active Takayasu's arteritis.
This trial compares a personalized treatment plan based on your specific disease markers to standard care, aiming to find which is more effective and safer for active Takayasu's arteritis. It may help researchers learn how to better control inflammation and prevent flares.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07704892RecruitingPhase 3
Study of efimosfermin for adults with cirrhosis from MASH
This trial tests a new drug, efimosfermin, to see if it is safe and effective for people with cirrhosis caused by MASH (a type of fatty liver disease). It may help improve liver health compared to a placebo.
Little Rock, ArkansasAges 18–75 - NCT07701993RecruitingPhase 3
Testing efimosfermin for MASH with compensated cirrhosis
This trial tests whether efimosfermin, an experimental drug, can safely help people with MASH (a fatty liver disease) that has led to cirrhosis (liver scarring) but the liver is still working well (compensated). Participants will be randomly assigned to receive the drug or a placebo.
Little Rock, ArkansasAges 18–75 - NCT07699601RecruitingPhase 2/Phase 3
Testing a pain tablet after orthopedic surgery
This trial tests an investigational tablet called HL-1186 for controlling pain after orthopedic surgery. It explores whether the drug can safely reduce moderate to severe pain when given after the procedure.
Changsha, HunanAges 18–75 - NCT07701967RecruitingPhase 4
Depemokimab for chronic sinusitis with nasal polyps
This trial tests a new antibody medicine (depemokimab) for Japanese adults with chronic sinusitis and nasal polyps. It aims to see if the drug alone can reduce symptoms without needing steroid nasal sprays.
EhimeAges 18 years+ - NCT07704099RecruitingPhase 2
Study of KER-065 for Duchenne Muscular Dystrophy
This study tests a new medication called KER-065 to see if it helps people with Duchenne Muscular Dystrophy (DMD). It may help boys and men who are still walking, as well as those who use a wheelchair, as long as they are on a stable corticosteroid treatment.
Auckland, North IslandAges 9 years+ - NCT06643416RecruitingPhase 3
Timolol cream for nail problems from lung cancer drugs
This trial tests if a timolol cream can help treat painful or infected nails (paronychia) caused by certain lung cancer medications. If you have non-small cell lung cancer and nail problems from your treatment, this study may offer relief.
Hong KongAges 18 years+ - NCT07704554Recruiting
Dural puncture epidural for labor pain relief
This study compares a modified epidural technique (dural puncture epidural) to the standard method for managing labor pain. It aims to see if the new approach is safer or works better for women in labor.
Columbus, OhioAges 18 years+ - NCT07703488Recruiting
Dydrogesterone for abnormal uterine bleeding in teens
This trial tests if dydrogesterone, a hormone pill, can safely help teenagers with heavy or irregular periods. If you or your child have had unusual bleeding that isn't caused by pregnancy or other medical issues, this study may provide treatment options.
Guangzhou, GuangongAges 10–19 - NCT07705243RecruitingPhase 3
Maintenance therapy for advanced nasopharyngeal cancer
This trial tests a combination of two drugs (becotatug vedotin and an anti-PD1 immunotherapy) as maintenance treatment after initial chemotherapy for advanced nasopharyngeal cancer that has spread or returned. It's for people whose disease has not progressed after standard first-line treatment.
Guangzhou, GuangdongAges 18–75 - NCT07703163RecruitingPhase 1
Canagliflozin for advanced solid tumors in patients with or without diabetes
This trial tests canagliflozin, a diabetes drug, combined with immunotherapy for people with advanced solid tumors. It may help if you have type 2 diabetes or are at risk, but you don't need diabetes to join.
Chengdu, SichuanAges 18–80 - NCT06207656RecruitingPhase 2
Targeted therapy for BRAF V600E mutated colorectal cancer
This trial tests if combining three targeted drugs (cetuximab, encorafenib, and binimetinib) before surgery can shrink or control cancer in people with a specific BRAF V600E mutation and a stable (MSS) tumor. It focuses on colorectal cancer that is either already able to be removed or could become removable with treatment.
MadridAges 18 years+ - NCT05558007RecruitingPhase 2
Topical treatment trial after prostate surgery in men
This Phase 2 study tests how safe and effective a topical medicine (BZ371A) is for men after prostate surgery, with the goal of improving sexual recovery and monitoring side effects. You may be able to join if you meet specific timing, health, and medication criteria after radical prostatectomy.
Belo HorizonteAges 40–65 - NCT07690059RecruitingPhase 2
Magnesium oral spray for chronic cough
This trial tests a magnesium salt oral spray (SC0032) for adults whose chronic cough has not responded to treatment or has no clear cause. It aims to see if the spray can reduce coughing frequency and improve symptoms.
BelfastAges 18–80
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.