Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06263959RecruitingPhase 2
Testing a new hepatitis B pill (GST-HG131) for chronic HBV
This study tests a new drug, GST-HG131, for people with chronic hepatitis B who are already on stable treatment. It aims to see if the drug is safe and reduces the virus further.
BeijingAges 35–65 - NCT07335588RecruitingPhase 3
Testing delgocitinib cream for lichen sclerosus
This trial tests a cream called delgocitinib for adults with lichen sclerosus in the genital area. It aims to see if the cream can safely and effectively reduce symptoms over 52 weeks.
Birmingham, AlabamaAges 18 years+ - NCT07340827RecruitingPhase 3
Comparing two fertility drugs in Japanese women with hormone deficiency
This study tests if a combination of two hormone drugs (follitropin alfa/lutropin alfa) works as well as another drug (hMG) for Japanese women with low LH and FSH levels who are doing in vitro fertilization (IVF). The goal is to help them produce eggs for pregnancy.
Akita, AkitaAges 18–42 - NCT07335211RecruitingPhase 3
Testing a new eye drop for glaucoma or high eye pressure
This trial tests a new medicine called HUC3-637 for people with primary open-angle glaucoma or ocular hypertension. It aims to see if it safely lowers eye pressure.
SeoulAges 19 years+ - NCT07337564RecruitingPhase 2
Study of SHR-1139 for ulcerative pyoderma gangrenosum
This study tests an investigational drug called SHR-1139 for adult patients with ulcerative pyoderma gangrenosum (a type of painful skin ulcer). The goal is to see if the drug is safe and helps heal the ulcers.
Jinan, ShandongAges 18 years+ - NCT07340463RecruitingPhase 2
Biologics vs standard therapy for lupus kidney disease
This trial tests two biologic drugs (belimumab or telitacicept) compared to a standard treatment (mycophenolate mofetil) for people with active lupus nephritis. The goal is to see if biologics work better at controlling kidney inflammation over 6 months.
Nanjing, JiangsuAges 14–65 - NCT07335731Recruiting
Safety and effectiveness of a new robot for weight-loss surgery
This trial tests a new robot-assisted device for weight-loss surgery in people with obesity. It aims to see if the device is safe and works well for metabolic conditions.
BeijingAges 18–65 - NCT07334587Enrolling by invitation
Comparing two chemotherapies for advanced colorectal cancer
This trial compares two chemotherapy drug combinations (FOLFOX-6 and CAPOX) to see which works better and has fewer side effects for people with colorectal cancer that has spread. It may help you and your doctor choose the best treatment option.
Lahore, Punjab ProvinceAges 20–70 - NCT07338344RecruitingPhase 2
Luspatercept with thalidomide for beta-thalassemia patients
This study tests whether a combination of two drugs, luspatercept and thalidomide, can help people with beta-thalassemia who need regular blood transfusions. It aims to reduce the number of transfusions needed.
Shenzhen, GuangdongAges 18–75 - NCT07337460RecruitingPhase 2
Icaritin plus chemotherapy for high-risk liver cancer after surgery
This trial tests combining a natural compound (Icaritin) with standard chemotherapy (mFOLFOX) after liver cancer surgery to lower the chance of the cancer coming back. It is for patients whose cancer had certain high-risk features, like a large tumor or cancer in blood vessels.
Yangzhou, JiangsuAges 18–75 - NCT07338175RecruitingPhase 3
Testing minocycline for brain bleeding recovery
This trial tests if the antibiotic minocycline can help people recover after a spontaneous brain bleed (intracerebral hemorrhage). It is for patients who have a moderate-sized bleed and are within 48 hours of symptoms starting.
Beijing, Beijing MunicipalityAges 18–80 - NCT03689842Recruiting
Testing living-donor uterine transplant for MRKH
This study tests whether transplanting a uterus from a living related donor can be done safely and can help patients with MRKH type I achieve pregnancy. It also checks risks and safety issues for both the donor and recipient.
SuresnesAges 18–65 - NCT06660719RecruitingPhase 3
New stroke medicine SP-8203 with clot-busting therapy
This trial tests a new medicine called SP-8203 added to standard clot-busting treatment for people having a moderate to severe stroke. The goal is to see if it helps improve recovery and is safe.
BusanAges 19–85 - NCT06852976RecruitingPhase 2
Gel treatment for diabetic foot ulcers study
This trial tests a new gel (MDI-1228-mesylate) applied to diabetic foot ulcers to see if it helps them heal faster than standard care alone. It is for people who have had a foot ulcer for at least 12 weeks and are already receiving standard treatment.
Durham, North CarolinaAges 18–75 - NCT06863532Recruiting
Comparing two add-on treatments for type 2 diabetes
This trial compares adding a new pill (cofrogliptin) to increasing your current metformin dose, for people whose blood sugar is still too high despite taking an SGLT2 inhibitor and a low dose of metformin. The goal is to see which option works better and is safer.
Hangzhou, ZhejiangAges 18–74 - NCT07326540RecruitingPhase 3
Testing a new antibiotic for drug-resistant pneumonia in the hospital
This trial compares a new antibiotic (BV100 plus low-dose polymyxin B) against a standard treatment for pneumonia caused by a hard-to-treat bacteria (Acinetobacter baumannii). If you have hospital-acquired or ventilator-associated pneumonia and standard antibiotics aren't working, this study may offer a new option.
TbilisiAges 18–82 - NCT07333118RecruitingEarly Phase 1
Testing GT801 for severe autoimmune diseases
This trial tests a new treatment called GT801, a type of CAR-T cell therapy, for people with moderate to severe autoimmune diseases that have not responded to standard treatments. It aims to see if GT801 can safely and effectively control the disease.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07326215Recruiting
A study of a device that removes carbon dioxide from the blood
This trial tests a device called PrismaLung+ that helps remove extra carbon dioxide from the blood of patients on breathing machines. It may help people whose lungs are struggling despite gentle ventilation settings.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07327359RecruitingPhase 1/Phase 2
Hair loss treatment for men with male pattern baldness
This study tests a new investigational drug, OLX72021, given as injections into the scalp, to see if it can help regrow hair in men with male pattern baldness. It will also check how safe the drug is and how well it works.
Botany, New South WalesAges 18–59 - NCT07332091RecruitingPhase 2
Study of vamifeport for adults with iron overload from hereditary hemochromatosis
This study tests an investigational drug called vamifeport to see if it can reduce iron levels in the body and improve outcomes for people with hereditary hemochromatosis (a genetic condition causing too much iron absorption). Participation may help manage iron overload and potentially reduce the need for regular blood removal treatments.
Gilbert, ArizonaAges 18 years+ - NCT07326995RecruitingPhase 2
Inhaled PA9159 for Adults with Moderate Asthma
This trial tests a new inhaled medicine called PA9159 for adults with moderate asthma. It compares the medicine to a placebo to see if it safely improves breathing and controls asthma symptoms.
Nanchang, JiangxiAges 18–75 - NCT07330934RecruitingPhase 2
Study of IBI356 for moderate to severe eczema
This study tests a new medication called IBI356 for people with moderate to severe eczema that hasn't improved with standard creams. The goal is to see if this medicine can safely reduce the redness, itching, and rash.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07327619RecruitingPhase 3
Testing a New Antibiotic Combo for Hospital-Acquired Pneumonia
This trial tests a combination of two antibiotics (meropenem and pralurbactam) to see if they work better than other treatments for people with pneumonia that started in the hospital or from a breathing machine. If you qualify, this study might offer you a new treatment option.
Huaihua, HunanAges 18–80 - NCT07331974Recruiting
A trial of Akkermansia for weight loss in overweight adults
This trial tests a supplement containing Akkermansia bacteria to see if it helps adults who are overweight or obese lose weight. It may be an option if you have not taken weight loss medications recently and are already trying to manage your weight with diet and exercise.
Guangzhou, GuangdongAges 18–60
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.