Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06952517RecruitingPhase 2
Clascoterone cream for rosacea bumps and pimples
This study tests a cream called clascoterone (already approved for acne) to see if it can help treat facial rosacea that causes bumps and pimples. Participants will use the cream daily and attend regular check-ups to see if their skin improves.
Brooklyn, New YorkAges 18 years+ - NCT04891237RecruitingPhase 3
Grass and olive allergy vaccine trial for teens to older adults
This Phase 3 trial tests whether an allergy treatment can reduce symptoms caused by grass and olive pollen. It also checks safety, especially for breathing and allergic reactions, in people with confirmed grass/olive allergy.
Tarancón, CuencaAges 12–65 - NCT06462417Recruiting
Testing arbidol for allergic rhinitis
This trial tests if arbidol, an antiviral medicine, can safely treat allergic rhinitis (hay fever). It might help if your nasal symptoms like sneezing or stuffiness are moderate to severe.
Wuhan, HubeiAges 18–65 - NCT07140913RecruitingPhase 3
Testing KarXT for bipolar I mania with mood stabilizers
This study tests whether adding KarXT to lithium, valproate, or lamotrigine helps calm manic episodes in people with bipolar I disorder. It aims to see if the combination is safe and works better than the mood stabilizer alone.
Bentonville, ArkansasAges 18–65 - NCT07140939RecruitingPhase 3
Reducing belly fat with an injection: CBL-514 trial
This trial tests a new injection called CBL-514 that is designed to reduce fat under the skin in the belly area. It might help people who are dissatisfied with stubborn abdominal fat that doesn't go away with diet and exercise.
Encinitas, CaliforniaAges 18 years+ - NCT07140328RecruitingPhase 2
Testing a new inhaler for COPD symptoms
This trial tests two forms of a new medication (HSK39004) in people with COPD. The goal is to see if they help improve breathing and are safe. Eligible participants must be between 40 and 80, have moderate to severe COPD, and be able to stop other COPD treatments during the study.
Nanchang, JiangsuAges 40–80 - NCT07140523RecruitingPhase 2
Testing a new blood thinner for knee replacement surgery
This study tests a new injection called SRSD107 to see if it prevents blood clots after knee replacement surgery, compared to a standard blood thinner (enoxaparin). It might be an option if you are having a planned knee replacement and are otherwise healthy.
Nové Město na MoravěAges 60–80 - NCT07140783RecruitingPhase 3
Eye drops to improve night vision after laser eye surgery
This study tests an eye drop that may help people who had laser eye surgery before 2010 and now have trouble seeing in dim light, such as glare, halos, or starbursts at night. The drops are given at home and may improve vision in low light.
Chandler, ArizonaAges 18 years+ - NCT07142304Recruiting
A study of compression gloves and boots to prevent chemo nerve damage
This trial is testing a wearable device (gloves and boots) that applies gentle compression to your hands and feet during chemotherapy. It aims to prevent or reduce nerve damage (numbness, tingling, pain) that some chemotherapy drugs can cause.
Poway, CaliforniaAges 18 years+ - NCT07137910RecruitingPhase 2
Study of AHB-137 for chronic hepatitis B
This trial tests a new injection called AHB-137 for people with chronic hepatitis B. It aims to see if the drug is safe and helps control the virus.
Beijing, Beijing MunicipalityAges 18–65 - NCT07142967Recruiting
MR-Linac radiotherapy for prostate cancer that returned after earlier radiation
This trial tests if a special MRI-guided radiotherapy machine (MR-Linac) can safely treat prostate cancer that has come back after previous radiation therapy. It may help men who have limited options and want to avoid more invasive treatments.
New York, New YorkAges 18 years+ - NCT07143773RecruitingPhase 4
SGLT2i safety in kidney transplant patients without diabetes
This study tests whether a medicine called SGLT2i (a type of pill for kidney health) is safe and helpful for kidney transplant recipients who do not have diabetes. It aims to see if it can improve how the new kidney works.
OdenseAges 18 years+ - NCT07138755RecruitingPhase 2
PD-1, chemo, and adaptive radiation for stage 3 lung cancer
This study tests if adding an immunotherapy drug (PD-1 inhibitor) to chemotherapy and specially planned radiation works better for stage 3 lung cancer that cannot be surgically removed. It may be an option if you have not had previous treatment for this cancer.
Changsha, HunanAges 18–75 - NCT07130032RecruitingPhase 2
Immunotherapy combo for advanced lung cancer or melanoma
This trial tests a combination of immunotherapy drugs (anti-PD-1/PD-L1 antibodies) plus bevacizumab and a low-dose chemotherapy called cyclophosphamide for people with advanced lung cancer or melanoma who have already been on immunotherapy and their cancer has progressed.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT07133308RecruitingPhase 3
Study of deuruxolitinib for teens with severe alopecia areata
This study tests an investigational oral medication (deuruxolitinib) for adolescents with severe alopecia areata (hair loss). It aims to see if it can help hair regrow safely.
Birmingham, AlabamaAges 12–17 - NCT07126912Recruiting
Alcarisa filler for mid-face volume restoration
This trial tests a new hyaluronic acid filler called Alcarisa to restore volume in the mid-face (cheek area). It may be a good option if you are looking for a non-surgical way to treat moderate to significant cheek volume loss.
Tehran, Tehran ProvinceAges 30–65 - NCT07132827RecruitingPhase 3
Study of SHR-1905 for chronic sinusitis with nasal polyps
This trial tests a new injection (SHR-1905) for people with chronic sinusitis and nasal polyps who still have symptoms despite using standard nasal spray treatments. It aims to see if the drug can reduce polyp size and improve symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07130604RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This trial tests an experimental pill called D-2570 for people with moderate to severe plaque psoriasis. It aims to see if the pill can safely improve skin symptoms like redness, scaling, and thickness.
Beijing, Beijing MunicipalityAges 18–70 - NCT07129382RecruitingPhase 1/Phase 2
Study of CS32582 for moderate to severe plaque psoriasis
This trial tests a new oral medication, CS32582, for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at reducing skin symptoms like redness, thickness, and scaling.
Beijing, Beijing MunicipalityAges 18–70 - NCT07132567Recruiting
Studying safety and effectiveness of Poteligeo for certain skin lymphomas
This study is tracking the safety and effectiveness of a drug called Poteligeo (mogamulizumab) for adults with mycosis fungoides or Sézary syndrome who have already tried at least one body-wide treatment. It is a post-market surveillance study, meaning the drug is already approved, and doctors are gathering real-world information about how well it works and any side effects.
Busan, Busan Metropolitan CityAges 19 years+ - NCT07131254RecruitingEarly Phase 1
Study of GT719 cell therapy for CD19-positive leukemia or lymphoma
This study is testing a new cell therapy called GT719 for people with B-cell leukemia or lymphoma that has not responded to standard treatments. The therapy targets a protein called CD19 on cancer cells, aiming to kill them.
Ganzhou, JiangxiAges 18–75 - NCT07132255Enrolling by invitation
Study of remote robot-assisted heart stent placement
This trial tests whether a doctor can use a robot to place a heart stent while being in a different location. It is designed for people who need a stent to open a blocked heart artery.
Jimsar, Xinjiang Uygur Autonomous RegionAges 18–80 - NCT07126782RecruitingEarly Phase 1
Gene-edited immune cells for AML after transplant
This trial tests a type of immune cell called gamma-delta T cells in people with acute myeloid leukemia who still have minimal residual disease after a stem cell transplant. The goal is to see if these cells can clear the remaining leukemia cells safely and effectively.
BeijingAges 18 years+ - NCT07128979RecruitingPhase 4
Studying butcher’s broom for moderate hemorrhoids
This study tests a plant-based medication made from butcher’s broom (Ruscus aculeatus) to see if it safely helps people with moderate hemorrhoids. If you have stage II or III hemorrhoids and are between 18 and 45, you may be able to join.
IstanbulAges 18–45
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.