Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07108127RecruitingPhase 2
Targeted drugs plus chemo for HER2-positive rectal cancer
This trial tests whether a combination of two targeted drugs (trastuzumab and pertuzumab biosimilars) plus chemotherapy can shrink advanced HER2-positive rectal cancer before surgery. It aims to improve response and potentially reduce the need for more aggressive treatments.
BeijingAges 18 years+ - NCT07106957Recruiting
B5 balm for rosacea with sensitive skin
This trial tests a B5 balm (CICAPLAST BAUME B5+) to see how well it helps people with rosacea and sensitive skin. It aims to reduce redness and improve skin comfort.
BeijingAges 18–55 - NCT07114159Recruiting
Sacral nerve stimulation for ulcerative colitis
This trial tests if sacral nerve stimulation can safely help people with ulcerative colitis that hasn't improved with standard treatments. It aims to see if this approach can reduce symptoms and improve quality of life.
Xi'an, ShaanxiAges 18–65 - NCT07107633RecruitingPhase 2
Imaging test for cancer spread in the abdomen
This trial tests a special imaging injection to see if it can better detect cancer that has spread to the lining of the abdomen in people with stomach or bowel cancer. If you are scheduled for surgery to remove or explore the cancer, this scan might help your doctor plan the best treatment.
ShanghaiAges 18 years+ - NCT07115082RecruitingPhase 1/Phase 2
Stem cells from amniotic fluid for early menopause
This study tests whether stem cells from the fluid around a baby (amniotic membrane) can help women with premature ovarian insufficiency improve their chances of getting pregnant. It is designed for women under 40 who have not had a period for months and have high FSH levels.
ShanghaiAges 20–40 - NCT06967012RecruitingPhase 4
Zonisamide as add-on treatment for children with epilepsy
This trial tests adding zonisamide to the current epilepsy medication for children aged 1 to 14 who still have focal seizures. The goal is to see if the combination works better and is safe.
Nantong, JiangsuAges 1–14 - NCT07096934RecruitingPhase 1/Phase 2
Testing a new cell treatment for stubborn diabetic foot ulcers
This trial tests a new treatment using special skin cells grown into tiny spheres (spheroids) to help heal diabetic foot ulcers that have not healed with standard care. It aims to see if this treatment is safe and works better than usual care.
Coffs Harbour, New South WalesAges 18–80 - NCT07102186RecruitingPhase 4
Adapalene plus hyaluronic acid gel for mild to moderate acne
This trial compares a gel containing adapalene (a retinoid) plus hyaluronic acid (a moisturizer) to adapalene gel alone for mild to moderate acne. It aims to see if adding hyaluronic acid helps reduce irritation and improve results.
Cairo, Cairo GovernorateAges Any age - NCT07104604RecruitingPhase 2
New combo before surgery for low rectal cancer
This trial tests a new combination of treatments (radiation, immunotherapy, and two chemotherapy drugs) given before surgery for people with a specific type of locally advanced rectal cancer that is close to the anus. The goal is to see if this approach is safe and effective.
Shantou, GuangdongAges 18–75 - NCT07099157RecruitingPhase 4
Brivudine for Shingles: Safety and Effectiveness Study
This trial tests whether the antiviral drug brivudine is safe and effective for treating shingles (herpes zoster). It compares brivudine to other antiviral treatments like famciclovir, and may be an option if you are looking for a shorter treatment course.
BeijingAges 18 years+ - NCT07098351Recruiting
A trial for a new itchy skin medicine for people on peritoneal dialysis
This trial tests if a medication called nalfurafine hydrochloride (taken as a tablet that melts in your mouth) can help reduce moderate to severe itching in people receiving peritoneal dialysis for chronic kidney disease.
Guangzhou, GuangdongAges 18–85 - NCT07097207RecruitingPhase 1/Phase 2
Study of CD19CD20-CAR-T for B-cell lymphoma
This trial tests a new type of cell therapy that targets two markers (CD19 and CD20) on lymphoma cells. It is for patients whose lymphoma has come back or has not responded to standard treatments.
Shenzhen, Other (Non U.s.)Ages 18–75 - NCT07105852RecruitingPhase 2
A new drug combo for advanced bile duct cancer
This trial tests a combination of two drugs, sacituzumab tirumotecan and pucotenlimab, for people with advanced bile duct cancer (including gallbladder cancer) that cannot be removed by surgery or has spread. The goal is to see if this treatment is safe and works well, especially for those with a protein called TROP2 on their cancer cells.
Hangzhou, ZhejiangAges 18 years+ - NCT07095933RecruitingEarly Phase 1
Everolimus for hard-to-control focal epilepsy
This study tests whether the medicine everolimus (taken as a pill) can safely reduce seizures in adults with focal epilepsy that hasn't been controlled by other treatments. You would continue your current seizure medicines and add everolimus.
Beijing, Beijing MunicipalityAges 18–60 - NCT07103382Recruiting
Testing if a clay mineral helps with weight loss in obesity
This study tests if a natural clay mineral called attapulgite can help people with obesity or overweight and type 2 diabetes lose weight. It aims to see if it is safe and effective.
Changsha, HunanAges 18–60 - NCT07100704RecruitingPhase 2
Nivolumab for recurrent olfactory neuroblastoma
This trial tests the drug nivolumab for people with a rare nasal tumor (olfactory neuroblastoma) that has come back or spread and cannot be treated with surgery or radiation. You must have already tried chemotherapy and it stopped working. The goal is to see if nivolumab can shrink the tumor or slow its growth.
Kashiwa, ChibaAges 18 years+ - NCT07097701RecruitingPhase 3
Comparing two forms of mexiletine for non-dystrophic myotonias
This trial compares a new extended-release (PR) form of mexiletine to the immediate-release (IR) form in people with non-dystrophic myotonias. The goal is to see if the longer-acting version works as well or better with fewer side effects.
LeuvenAges 16 years+ - NCT07102628RecruitingPhase 3
Early cholesterol treatment after heart attack
This study tests whether giving a new cholesterol-lowering drug, inclisiran, early during a hospital stay after a heart attack can help lower bad cholesterol (LDL) more effectively than usual care. It may reduce the risk of future heart problems.
Capital Federal, Buenos AiresAges 18 years+ - NCT07102901RecruitingPhase 2
Study of SHR2554 with other therapies for gastric or junction cancer
This trial tests a new drug, SHR2554, combined with other anticancer treatments for advanced stomach or gastroesophageal junction cancer. It aims to see if the combination is safe and effective. You may qualify if you have measurable disease and are generally in good health.
Harbin, HeilongjiangAges 18–75 - NCT07102511Enrolling by invitationPhase 3
Testing a new cholesterol drug in children with high cholesterol
This trial tests if a new medicine, lerodalcibep, can safely lower cholesterol in children ages 6 to 17 who have a genetic condition called heterozygous familial hypercholesterolemia (HeFH). It aims to help children whose cholesterol stays high despite taking standard cholesterol-lowering drugs.
Cincinnati, OhioAges 6–17 - NCT07105215RecruitingPhase 1/Phase 2
Testing RC278 for Solid Tumors
This study tests a new drug called RC278 for people with solid tumors that have not spread to the brain. It aims to see if the drug is safe and effective, and may be an option for those who are otherwise fairly healthy.
Beijing, Beijing MunicipalityAges 18–75 - NCT06696417Recruiting
Testing vunakizumab for moderate to severe plaque psoriasis
This study tests a new drug called vunakizumab to see if it is safe and works well for people with moderate to severe plaque psoriasis. If you have not used biologic treatments before and meet other health requirements, you may be able to join.
Shenyang, LiaoningAges 18 years+ - NCT06757504RecruitingPhase 2
Testing TTYP01 tablets for autism in kids and teens
This study tests an investigational tablet (TTYP01) to see if it can help adolescents and children with autism spectrum disorder (ASD). The goal is to find out if the drug improves symptoms and is safe for this age group.
BeijingAges 6–16 - NCT06911255RecruitingPhase 1/Phase 2
Testing two immunotherapy drugs with chemoembolization for liver cancer
This trial tests whether adding two immunotherapy drugs (tremelimumab and durvalumab) to a standard liver cancer treatment called TACE can help people with liver cancer that cannot be removed by surgery. TACE uses tiny particles to block the blood supply to the tumor and delivers chemotherapy directly to the liver.
SeoulAges 19 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.