Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,831 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06440759Recruiting
Filter Comparison for Septic Shock with Kidney Failure
This study compares two types of filters used during continuous kidney replacement therapy in patients with septic shock and severe acute kidney injury. The goal is to see which filter works better and is safer.
Kubang Kerian, KelantanAges 18 years+ - NCT06440746RecruitingPhase 2/Phase 3
Testing olokizumab for progressive lung scarring diseases
This trial tests a drug called olokizumab to see if it can slow down worsening lung scarring (fibrosis) in people with certain types of progressive interstitial lung diseases. It's for patients whose lung function has declined despite current treatments.
BarnaulAges 18 years+ - NCT06441630RecruitingPhase 3
Testing two new high blood pressure medicines together
This trial tests a combination of two new medications (AD-227A and AD-227B) to see if they work better together for people with essential (common) high blood pressure. It could be a new treatment option to help control your blood pressure.
SeoulAges 19 years+ - NCT06443307Recruiting
Study of Liposomal Irinotecan in Advanced Colorectal Cancer
This study tests a new form of chemotherapy called liposomal irinotecan (Nal-IRI) for people with advanced colorectal cancer or other solid tumors. The goal is to see how well it works and how safe it is in real-world settings.
Beijing, Beijing MunicipalityAges Any age - NCT06443606RecruitingPhase 3
Bezafibrate for primary biliary cholangitis with incomplete UDCA response
This trial tests if adding bezafibrate (200 mg or 400 mg) to standard UDCA treatment can improve liver function in people with primary biliary cholangitis whose UDCA alone isn't working well enough.
ParisAges 18–80 - NCT06445881RecruitingPhase 2
Herbal medicine for lung cancer before and after surgery
This trial is testing whether adding a traditional Chinese herbal formula (Modified Si Jun Zi Tang) to standard treatment before and after surgery can help people with early-stage non-small cell lung cancer. It aims to see if the herbs improve outcomes and reduce side effects.
Hangzhou, ZhejiangAges 18–75 - NCT06450145Recruiting
Combination treatment for arsenic-resistant APL
This trial tests if combining interferon-α with arsenic trioxide (ATO) can help people whose acute promyelocytic leukemia (APL) has stopped responding to arsenic treatment. If you have this type of leukemia that came back or didn't get better after arsenic therapy, this study may offer a new option.
Hangzhou, ZhejiangAges 18–70 - NCT06451146Recruiting
Orbital atherectomy for calcified heart blockages
This trial studies a procedure called orbital atherectomy to treat hardened calcium deposits in heart arteries. It aims to help people with moderately to severely calcified blockages.
Legnica, Lower Silesian VoivodeshipAges 18 years+ - NCT06451718Recruiting
A new implant for keratoconus to avoid corneal transplant
This trial tests a small metal implant placed in the cornea to treat keratoconus, a condition where the cornea thins and bulges. The goal is to see if the implant can safely improve vision and prevent the need for a corneal transplant.
Roma, RomaAges 18 years+ - NCT06452316RecruitingPhase 1
Eye drop study for limbal stem cell deficiency
This study tests a new eye drop called CSB-001 for people with limbal stem cell deficiency (LSCD), a condition that damages the cornea. The goal is to see if the drops can help improve the health of the cornea and reduce inflammation.
Loma Linda, CaliforniaAges 18 years+ - NCT06455449RecruitingPhase 3
Injectable anifrolumab for polymyositis or dermatomyositis
This study tests a new injectable medicine (anifrolumab) added to your usual treatments for polymyositis or dermatomyositis. It may help reduce disease activity if you have moderate to severe symptoms and are already on stable therapy.
Phoenix, ArizonaAges 18–75 - NCT06456593RecruitingPhase 2
Obefazimod for moderate to severe Crohn's disease
This trial tests an experimental oral medication called obefazimod for people with moderate to severe Crohn's disease. It aims to see if the drug can reduce inflammation and improve symptoms when other treatments have not worked well.
Fairhope, AlabamaAges 18–75 - NCT06458972Recruiting
Telitacicept for lupus: safety and effectiveness trial
This trial tests a new biologic drug called telitacicept for people with systemic lupus erythematosus (SLE). It aims to see how safe and effective the drug is and may offer a new treatment option for lupus.
Wuhan, HubeiAges 18–70 - NCT06461910RecruitingPhase 2
Immunotherapy, thymalfasin, and chemo before surgery for stomach cancer
This trial is testing a combination of three medicines—an immunotherapy (anti-PD-1), an immune booster (thymalfasin), and a chemotherapy regimen (SOX)—given before surgery to shrink stage III stomach or gastroesophageal junction cancer and improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT06462183RecruitingPhase 1
Study of RGT-61159 for Advanced ACC or CRC
This trial tests a new drug called RGT-61159 for adults with adenoid cystic carcinoma or colorectal cancer that has returned or stopped responding to treatment. The goal is to see if the drug is safe and effective in shrinking tumors.
Boston, MassachusettsAges 18 years+ - NCT06462417Recruiting
Testing arbidol for allergic rhinitis
This trial tests if arbidol, an antiviral medicine, can safely treat allergic rhinitis (hay fever). It might help if your nasal symptoms like sneezing or stuffiness are moderate to severe.
Wuhan, HubeiAges 18–65 - NCT06463522RecruitingPhase 1/Phase 2
Immune cell therapy for liver cancer
This trial tests using your own immune cells (tumor-infiltrating lymphocytes) to fight advanced liver cancer. It may help if you have Barcelona Clinic Liver Cancer (BCLC) stage B or C and your liver function is still fairly good.
BeijingAges 18–70 - NCT06467409RecruitingPhase 2
Study of LPM3480392 for pain after knee surgery
This trial tests an injection called LPM3480392 to see if it safely reduces moderate to severe pain after knee replacement or ligament repair surgery. It aims to help people who need strong pain relief after this type of surgery.
WuhanAges 18 years+ - NCT06471088Recruiting
Safety check for Dovprela in real-world use
This study monitors how well the drug Dovprela (pretomanid) works and how safe it is when doctors prescribe it normally for drug-resistant tuberculosis. It gathers information from patients already taking the medication as part of their regular treatment.
SeoulAges Any age - NCT06472323Recruiting
Pulsed radiofrequency with platelet-rich plasma for trigeminal neuralgia
This trial tests a treatment that combines pulsed radiofrequency and platelet-rich plasma to see if it works better for trigeminal neuralgia pain that hasn't been helped by standard medicines like carbamazepine.
Beijing, Beijing MunicipalityAges 18–75 - NCT06472908RecruitingPhase 3
Colchicine after stent procedure for heart disease
This trial tests whether colchicine (a medicine used for gout) can help prevent heart problems after a stent procedure (PCI). It's for people who are in the hospital getting a stent and follow standard heart care.
Lanzhou, GansuAges 18–80 - NCT06474507Recruiting
Calculus Bovis Sativus for Stroke Recovery
This study tests an investigational traditional Chinese medicine called Calculus Bovis Sativus (CBS) for people who have had an ischemic stroke or have small vessel disease in the brain. It aims to see if CBS can help recovery and is safe to use.
Wuhan, HubeiAges 18 years+ - NCT06474520Recruiting
Bovine gallstone extract for inflammatory brain disease
This trial tests a natural substance called Calculus Bovis Sativus (CBS) to see if it helps people with certain inflammatory brain conditions like multiple sclerosis, neuromyelitis optica, MOGAD, or ADEM. The goal is to find out if it is safe and effective.
Wuhan, HubeiAges 18 years+ - NCT06474884Recruiting
Single blood thinner after shielded stent for brain aneurysm
This study is testing whether using only one blood-thinning medication (single antiplatelet therapy) after placing a special stent (Pipeline Flex with Shield) is safe and effective for treating unruptured brain aneurysms. It is for people who have already been on two blood thinners for a few days before the stent placement.
BeijingAges 18–80
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,831 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.