Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06242379RecruitingPhase 1/Phase 2
Testing stem cell particles for retinitis pigmentosa
This trial tests whether tiny particles from stem cells, called extracellular vesicles, can help people with retinitis pigmentosa. It aims to see if these particles are safe and can improve vision.
Bangkok Noi, BangkokAges 18 years+ - NCT07089186RecruitingPhase 3
Study of meropenem and pralurbactam for certain antibiotic-resistant infections
This trial tests a combination of two antibiotics (meropenem and pralurbactam) for treating serious infections caused by bacteria that are resistant to many other antibiotics. It may be an option for hospitalized patients with pneumonia, urinary tract infections, abdominal infections, or bloodstream infections.
ShanghaiAges 18–80 - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Scottsdale, ArizonaAges 1–25 - NCT07090161RecruitingPhase 2
Study of iloperidone for uncontrolled high blood pressure
This trial tests if iloperidone can lower blood pressure in people whose high blood pressure is not controlled by current medications. You may qualify if your blood pressure is still high after weeks of treatment.
Phoenix, ArizonaAges 18–65 - NCT07093476RecruitingPhase 3
Adding empagliflozin to improve blood sugar control
This trial tests whether adding empagliflozin (a diabetes pill) to your current medicines (alogliptin and metformin) helps manage blood sugar better. It may be an option if your blood sugar is not well controlled with your current treatment.
SeoulAges 19 years+ - NCT07091825Recruiting
Lubricating drops for rigid gas permeable contact lens wearers
This trial tests a new lubricating eye drop for people who wear rigid gas permeable (RGP) contact lenses. The drops are meant to make wearing the lenses more comfortable and less dry.
Beijing, Beijing MunicipalityAges 8 years+ - NCT07090005Recruiting
Endoscopic weight loss: comparing EndoZip and Apollo ESG
This study compares two different endoscopic procedures (EndoZip and Apollo ESG) to help obese patients lose weight. Both are done through the mouth without cutting the skin, and the goal is to see which works better and is safer.
Los Angeles, CaliforniaAges 21–65 - NCT07093138RecruitingPhase 4
CBD cream for migraine attacks
This trial tests whether a cream made with cannabidiol (CBD) can help stop migraine attacks. It is for people aged 18 to 55 who have had migraines for at least a year and get 2 to 8 attacks per month.
TehranAges 18–55 - NCT07094087RecruitingPhase 3
Blood clotting medicine for heart surgery bleeding
This trial tests a medicine called 4F-PCC to stop bleeding during complex heart surgery that uses a heart-lung machine. It could help people who have bleeding problems after the surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07086313RecruitingPhase 2/Phase 3
Testing a new ADHD drug for children
This trial tests an experimental drug (EB-1020) for children with ADHD. It aims to see if the drug is safe and effective in reducing ADHD symptoms.
SapporoAges 6–17 - NCT07094763Recruiting
Tenecteplase for posterior stroke 4.5-24 hours after onset
This trial tests a clot-busting drug called tenecteplase for people who had a stroke affecting the back part of the brain (posterior circulation). It may be an option if you can get treatment between 4.5 and 24 hours after symptoms started.
HefeiAges 18–100 - NCT07094438RecruitingPhase 1
Brain stimulation and neck surgery for severe Alzheimer's
This early-stage trial tests combining deep brain stimulation (a device that sends electrical pulses to the brain) with a neck surgery that aims to improve brain fluid drainage. It's for people with severe Alzheimer's who can still walk and do not have other major health issues.
BeijingAges 40–80 - NCT07088081Enrolling by invitation
Immunotherapy drugs for advanced liver cancer
This trial tests two types of immunotherapy (atezolizumab with bevacizumab or durvalumab with tremelimumab) for people with advanced liver cancer that hasn't been treated with systemic therapy before. It aims to see if these treatments are safe and effective.
Cairo, AbbasyaAges 18 years+ - NCT07089381Recruiting
Resveratrol for rheumatoid arthritis
This study tests whether resveratrol (a natural substance found in grapes) can help control moderate-to-high rheumatoid arthritis when added to your current RA medications. It aims to see if it reduces disease activity safely.
CairoAges 18 years+ - NCT07093866RecruitingPhase 2
Targeted drug combo for advanced prostate cancer
This trial tests a combination of two drugs—disitamab vedotin (a targeted antibody-drug that attacks HER2-positive cancer cells) and abiraterone (a hormone therapy)—to see if they can slow or shrink prostate cancer that has spread and become resistant to standard treatments.
Nanjing, JiangsuAges 18–75 - NCT06969534RecruitingPhase 2
Pucotenlimab for children with LECC cancer
This trial tests a new immunotherapy drug, pucotenlimab, for children and teens with a rare cancer called lymphoepithelioma-like carcinoma (LECC). The goal is to see if the drug is safe and helps shrink tumors.
Guangzhou, GuangdongAges 1–18 - NCT06972940Recruiting
Study of a gel to improve temple hollowing in Chinese adults
This trial tests a gel made from polycaprolactone (a safe, dissolvable material) to see if it can safely and effectively fill in hollow temples. It may be an option if you have flat or sunken temples and want a non-surgical treatment.
Beijing, Beijing MunicipalityAges 18–65 - NCT06251115Recruiting
Study of QY-1-T for advanced HBV-related liver cancer
This study tests a new treatment called QY-1-T for people with advanced liver cancer related to hepatitis B. It is for patients who have already tried other standard treatments and have a certain genetic marker (HLA-A*11:01).
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06976671RecruitingPhase 2
Testing bevacizumab injection for frozen shoulder
This trial tests an injection of bevacizumab into the shoulder joint for people with frozen shoulder (adhesive capsulitis). The goal is to see if it can reduce pain and stiffness.
North Ryde, New South WalesAges 18 years+ - NCT07085559RecruitingEarly Phase 1
Metabolically armed BCMA CAR-T for relapsed plasma cell cancer
This trial tests a new type of CAR-T cell therapy (Meta10-BCMA) that is "metabolically armed" to better fight cancer cells. It's for people with plasma cell cancers that have come back or not responded to multiple prior treatments, and whose cancer cells carry the BCMA protein.
Hefei, AnhuiAges 19–75 - NCT07082192RecruitingPhase 2/Phase 3
Testing CB03-154 for adults with ALS
This trial tests a new medicine, CB03-154, to see if it can help people with ALS. Researchers are comparing different doses to find the safest and most effective one.
Beijing, Beijing MunicipalityAges 18–65 - NCT07082114RecruitingPhase 3
Testing a new tablet for type 2 diabetes
This study tests a new pill called HDM1002 for adults with type 2 diabetes. It aims to see if it helps control blood sugar when added to your current metformin treatment.
Yueyang, HunanAges 18–75 - NCT07082725RecruitingPhase 3
Study of oral nizubaglustat for Niemann-Pick type C
This study tests an oral medication called nizubaglustat for people with Niemann-Pick type C disease who cannot take or are not satisfied with the current treatment miglustat. It aims to see if the drug can help with symptoms like coordination and movement problems.
Oakland, CaliforniaAges 4 years+ - NCT07081997RecruitingPhase 3
Higher-dose palopegteriparatide for hypoparathyroidism
This trial is for adults with hypoparathyroidism who are already taking a drug called palopegteriparatide (TransCon PTH) at a certain dose. It tests whether higher doses of this drug can better control calcium levels and reduce the need for other supplements.
Greeley, ColoradoAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.