Clinical trials
Emphysema clinical trials
Below are recruiting emphysema clinical trials, each written for real people, not researchers. We’re tracking 41 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06505603Recruiting
PiMZ alpha-1 deficiency progression study
This study is looking at people with a specific mild form of alpha-1 antitrypsin deficiency (PiMZ) to understand how their lung disease progresses over time. It involves lung function tests and CT scans, and may help researchers learn more about the condition.
Birmingham, AlabamaAges 18 years+ - NCT06349174Recruiting
Lung valve treatment for severe COPD
This study tests whether placing tiny valves in the airways can help people with severe COPD breathe easier. It is for people who still have trouble breathing despite quitting smoking and completing pulmonary rehab.
Beijing, Beijing MunicipalityAges 40–85 - NCT06181357Recruiting
Comparing one-step vs. two-step valve placement for severe emphysema
This trial tests whether placing ZEPHYR® valves in two stages reduces the risk of a collapsed lung (pneumothorax) compared to the usual one-stage procedure. It is for people with severe emphysema who have already quit smoking and meet specific lung function criteria.
BordeauxAges 35–80 - NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
CagliariAges 18 years+ - NCT05257681Recruiting
Repairing a lung airspace after failed bronchoscopic treatment
This study looks at a procedure to “complete” a lung fissure in people whose prior bronchoscopic lung volume reduction did not work as well as hoped. It may help reduce persistent shortness of breath, but eligibility depends on your lung test results and overall heart/lung safety.
Boston, MassachusettsAges 40–75 - NCT04930289Enrolling by invitation
Lung transplant registry for better donor lung preservation
This study builds a worldwide database to track and improve how donor lungs are preserved before transplant. Your information may help doctors choose and manage donor lungs more effectively.
Phoenix, ArizonaAges Any age - NCT04761393Recruiting
Testing a lung protein in COPD sputum samples
This study looks at a lung protein called MMP12 in sputum (mucus) to better understand COPD. It may help researchers learn which COPD changes are linked to disease severity and lung damage.
Hamilton, OntarioAges 40–85 - NCT04302272Recruiting
Study for people with severe emphysema and limited lung collateral airflow
This registry study follows adults with severe emphysema who have shortness of breath and low natural “backup” airflow between parts of the lung. It may help better understand how a specific FDA-approved treatment works for the right patients over time.
Phoenix, ArizonaAges 18 years+ - NCT04200079Recruiting
Long-term follow-up study for people with COPD
This study follows people with COPD over time to better understand their lung health and how it changes. It may help researchers and doctors learn what factors affect breathing and long-term outcomes.
Kingston, OntarioAges 40–85 - NCT04214587Recruiting
Study of removed lung valves after treatment
This study looks at lung tissue taken out after a treatment that places a one-way lung valve to help breathing. They want to learn how the valve affects the airway and lung over time.
GroningenAges Any age - NCT07731958Recruiting
One vs both lungs surgery for emphysema
This trial compares removing damaged parts of one lung versus both lungs to help people with severe COPD breathe better. It looks at which approach gives better results with fewer risks.
CopenhagenAges 18–75 - NCT03318406Recruiting
Registry for patients with uneven emphysema lung damage
This study follows people with uneven emphysema to better understand outcomes and safety after treatment. If you qualify, you’ll share health information and may undergo lung imaging before and after treatment.
ViennaAges 18 years+ - NCT03500731RecruitingPhase 1/Phase 2
Lung and bone marrow transplant for lung and blood failure
This Phase 1/2 study tests a special lung-and-bone-marrow transplant approach for people with severe lung disease and bone marrow failure (low blood counts). The goal is to see if the treatment is safe and whether it can improve outcomes when standard long-term immune-suppressing medicines are a poor fit.
Pittsburgh, PennsylvaniaAges 18–60 - NCT02796937Enrolling by invitationPhase 3
Long-term safety study of a blood protein for Alpha-1
This study checks how safe a prescribed blood protein medicine (alpha-1 proteinase inhibitor) is over the long term in people with Alpha-1 antitrypsin deficiency. You may join if you already finished an earlier study or if your lung function has been declining.
Phoenix, ArizonaAges 20–72 - NCT02803242Recruiting
Patient research network for people with lung symptoms
This trial enrolls adults to help build a patient-powered research network for chronic lung disease. If you join, you’ll likely be asked to complete surveys or provide information to help researchers learn how symptoms and health outcomes change over time.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02815683Recruiting
Bronchoscopy treatment with one-way lung valves
This study looks at outcomes from placing one-way valves in the lungs using a camera procedure through the airways (bronchoscopy). If you’re already planned for this type of valve treatment, you may be able to join to help researchers learn how it works.
GroningenAges Any age - NCT07597187Recruiting
Analyzing lung tissue samples to improve chronic lung disease diagnosis
This study uses a new imaging technology called LIBS to examine lung tissue samples that were already removed as part of your regular care. The goal is to see if this method can help doctors better understand and diagnose chronic lung diseases like interstitial lung disease, sarcoidosis, or emphysema.
GrenobleAges 18 years+
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Common questions
- Are there clinical trials for emphysema?
- Yes. Clin2 currently lists 41 recruiting emphysema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a emphysema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a emphysema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.