Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03512132Recruiting
Test HDL function in type 1 diabetes with kidney changes
This study looks at how well “good cholesterol” (HDL) works in people with type 1 diabetes, especially when kidney tests show early or more advanced damage. Researchers will compare different groups (normal, micro-, and macro-albumin in urine) to better understand HDL’s role and how it may relate to kidney health.
DijonAges 18 years+ - NCT03513003Recruiting
Pacifier use to improve misaligned baby teeth
This study tests whether using a pacifier can help correct common misalignments in young children’s baby teeth and bite. It may help children whose upper and lower teeth don’t meet properly, with or without tongue thrust.
BaselAges 2–5 - NCT03527420Recruiting
Study of body fat, blood vessels, and DNA changes
This study looks at how having a high body mass index affects blood vessel function and changes in DNA. It may help researchers understand why weight-related health risks happen and how bariatric surgery could help.
Chicago, IllinoisAges 18–50 - NCT03528226Recruiting
Exercise program to improve blood vessel function in type 1 diabetes
This trial studies whether an exercise training program can improve how well your blood vessels work in people with type 1 diabetes. It may help assess benefits beyond blood sugar control.
LilleAges 18–50 - NCT03610763Recruiting
Training brain recovery after arm nerve repair
This study tests a way to help your brain and nerves work better after an arm/hand nerve repair that is already in the long-term (chronic) recovery stage. It may help improve hand and arm function by targeting “neuroplasticity,” meaning the brain’s ability to adapt after injury.
Louisville, KentuckyAges 18 years+ - NCT03614962Recruiting
Warmth and TENS to improve thinking in dementia
This study tests whether using a warmth treatment and a gentle electrical nerve-stimulation device (TENS) can improve thinking and memory in people with mild to moderate dementia. It may help by supporting brain and nerve function, alongside your usual care.
Hong KongAges 65 years+ - NCT03622879Recruiting
Mirror therapy plus mild skin stimulation for leg movement after stroke
This trial tests whether using a mirror together with mild electrical stimulation on the skin can improve lower-limb movement after stroke. You may be eligible if you can already lift your ankle a bit and walk independently, and if certain thinking, vision, and skin issues are not present.
Hong KongAges 55–85 - NCT03680872Recruiting
Brain-to-nerve study to improve hand movement after spinal injury
This trial tests a “neural bypass” approach to help restore hand movement and feeling in people with tetraplegia from a spinal cord injury. You would have repeated visits for brain/nerve testing and may receive study procedures to see if function improves.
Manhasset, New YorkAges 22–65 - NCT03716128Recruiting
Testing bone hormone changes in people with kidney problems
This study checks how kidney disease affects bone health by measuring hormones like PTH and related blood markers. It may help doctors better diagnose bone problems that can occur with poor kidney function.
HerlevAges 18 years+ - NCT03725527Recruiting
Nerve block test to improve breathing after belly surgery
This trial studies whether a numbing injection near the abdominal muscle (rectus sheath block) helps your breathing and diaphragm function after elective upper belly surgery. If you qualify, you may receive or not receive this pain/nerve block as part of the study.
Asyut, Assiut GovernorateAges 18–50 - NCT03775837Recruiting
Ginseng extract to improve abnormal liver blood tests
This trial studies whether a Panax ginseng extract can improve liver-related blood test results in adults. It may help people with mildly to moderately elevated liver enzymes, while carefully excluding people with other liver causes.
YangsanAges 19–75 - NCT03778944Recruiting
Improving kidney graft function during donor kidney surgery
This study looks at ways to help a donated kidney work better after transplant. It is intended for people who are receiving a living-donor kidney transplant due to kidney failure.
CairoAges 18–60 - NCT03800017Recruiting
Muscle strength and exercise function in lung scarring
This study looks at how well skeletal (muscle) function supports exercise in people with interstitial lung diseases (including idiopathic pulmonary fibrosis). It may help better understand fitness and breathing limits, which can guide rehabilitation choices and future care.
Vancouver, British ColumbiaAges 40–80 - NCT03825458Recruiting
Study tracking hepatitis B viral RNA in blood
This study builds a group of people to measure small hepatitis B “viral RNA” signals in the blood. The goal is to see if these measurements could help researchers find a functional cure and better understand who may respond over time.
LyonAges 18 years+ - NCT03841981Recruiting
Body fat and female hormone function study
This study looks at how body fat and exercise relate to how your ovaries work and how your hormones function. It may help explain why some women have irregular ovulation or hormone problems, and how lifestyle factors affect them.
Madrid, MadridAges 18–40 - NCT03857529Recruiting
Rehab training for stroke arm control using brain and hand stimulation
This study tests whether non-invasive brain stimulation plus a hand/arm electrical stimulation device can improve how well your stroke-affected arm and hand move during therapy tasks. You would take part in screening and then receive these combined rehab approaches to see if motor control improves.
Cleveland, OhioAges 21 years+ - NCT03914378Recruiting
Study how radiation and cisplatin affect hearing in head and neck cancer
This study looks at how radiotherapy, and possibly cisplatin chemotherapy, affect hearing in people treated for head and neck cancer. It may help doctors better predict hearing side effects and plan hearing monitoring or prevention.
ManchesterAges 18 years+ - NCT03949400Recruiting
Exercise therapy and a soft knee brace for knee arthritis
This study tests whether an exercise program plus education, along with a soft brace, helps improve symptoms and function in adults with knee osteoarthritis. It may help people who have knee pain by combining movement training with daily support.
Aalborg, NothernAges 18 years+ - NCT03977207Recruiting
Thyroid hormone supplement for people on dialysis
This trial tests whether taking a thyroid hormone supplement helps people who are on hemodialysis and have borderline-high thyroid lab results (high TSH but normal FT4). It’s studying whether treatment changes thyroid-related outcomes or health while on dialysis.
Orange, CaliforniaAges 18–75 - NCT03979235Recruiting
Rehab effectiveness programs for people after stroke
This trial is testing rehabilitation programs by studying how well they work for people with movement problems after a stroke. You may be able to join if you can complete the rehab assessment and follow testing instructions.
BeijingAges 18–80 - NCT03980457Recruiting
Exoskeleton walking therapy for stroke recovery
This trial studies whether assisted walking training with an exoskeleton can improve recovery after stroke, especially for walking and daily function. You may be offered therapy once you are medically stable, able to stand, and able to participate safely.
Oklahoma City, OklahomaAges 18–90 - NCT04005469RecruitingPhase 1/Phase 2
Treprostinil to protect kidneys during transplant injury
This early-phase study tests whether treprostinil (Remodulin®) can reduce injury to a transplanted kidney right after surgery. If it works and is safe, it may help improve outcomes for people receiving a deceased-donor kidney transplant.
Providence, Rhode IslandAges 18–75 - NCT04006561Recruiting
Brain lymphoma study using targeted whole-brain radiation
This trial studies how newly diagnosed primary central nervous system (brain) non-Hodgkin lymphoma responds to a specific type of radiation to the whole brain, and it also looks at changes in thinking, mood, and behavior. It may help doctors understand how this treatment affects day-to-day brain function.
TaoyuanAges 18–80 - NCT03228290Recruiting
Liver transplant care study using patient function check
This study looks at how people with liver disease function day to day, especially around liver transplant care. It may help improve how doctors assess readiness and recovery needs.
Little Rock, ArkansasAges 18 years+
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.