Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 477 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05867901Recruiting
Test stopping imatinib early using blood DNA tests
This trial studies whether some people with high-risk GIST can safely take a “drug holiday” (pause imatinib) after surgery. They use a blood test looking for leftover cancer DNA to help decide who may benefit from stopping treatment.
Beijing, Beijing MunicipalityAges 18–75 - NCT05878977Recruiting
Testing biomarkers in immunotherapy for advanced melanoma
This trial looks at tissue and scan-related markers (“biomarkers”) to better understand how immunotherapy works in people with advanced melanoma. You may receive standard first-line immunotherapy, and your recent scans and health details will help researchers study why some people respond better than others.
LjubljanaAges 18 years+ - NCT05905016Recruiting
Testing an endoscopy procedure for gut movement problems
This study looks at how useful the POEM procedure is for people with gut “motility” (trouble moving food through the digestive tract). If you’re already scheduled for POEM, your team will also track how well it helps and whether it’s practical in real care.
Orlando, FloridaAges 18 years+ - NCT05972291Recruiting
Study gut changes in Gulf War illness with chronic stomach symptoms
This study looks at what’s driving Gulf War illness, focusing on gut symptoms like belly pain, diarrhea, and bloating. It may help researchers test approaches aimed at gut barrier function in eligible veterans.
Memphis, TennesseeAges 18–65 - NCT05978141Recruiting
T-cell lymphoma registry study
This study creates a registry for people with certain T-cell or NK-cell lymphomas. It collects health information and tumor samples to learn more about these diseases and improve future treatments.
Duarte, CaliforniaAges Any age - NCT05984589Recruiting
Health coaching for colorectal cancer survivors
This study tests a personalized health coaching program for people who have had colorectal or other gastrointestinal cancer. It helps you work on lifestyle habits like diet, exercise, and alcohol use to improve your health.
Los Angeles, CaliforniaAges 18 years+ - NCT05989763Recruiting
Constipation study for people with systemic sclerosis
This study looks at why people with systemic sclerosis (a disease that can affect connective tissues) develop constipation. It will use special tests to measure how well the colon moves waste, and it may help doctors find better treatments.
Houston, TexasAges 18 years+ - NCT05996458Recruiting
Combined screening for stomach and colon cancers
This study aims to find a better way to screen for stomach and colon cancers. You will be asked to provide a stool sample, and possibly have an endoscopy (a camera test), to see if combined screening can catch cancer early.
Zhaoqing, GuangzhouAges 45–70 - NCT06008054RecruitingPhase 2
New drug combo for advanced gastrointestinal cancers
This trial tests two new drugs (BL-B01D1 and SI-B003) alone or with a standard immunotherapy for advanced gastrointestinal cancers. The goal is to see if these combinations shrink tumors and are safe.
Beijing, Beijing MunicipalityAges 18–75 - NCT06015971Recruiting
Omega-3 and nutrition support for gastrointestinal cancer
This trial tests whether adding omega-3 fatty acids and extra nutrition support can help people with gastrointestinal cancer who have lost weight. It aims to improve strength and well-being during treatment.
Córdoba, CordobaAges 18 years+ - NCT06028737RecruitingPhase 2/Phase 3
Chemotherapy before surgery for advanced stomach cancer
This trial tests a combination of chemotherapy drugs given before surgery for locally advanced stomach or gastroesophageal junction cancer. It aims to see if this approach helps shrink the tumor and improve outcomes.
VilniusAges 18–80 - NCT06031402Recruiting
Best time for endoscopy for liver cirrhosis bleeding
This study is testing the best timing for an endoscopy (a tube with a camera used to look inside your digestive system) in people with liver cirrhosis and bleeding from enlarged veins. It aims to improve outcomes for patients with this type of emergency bleeding.
Shenyang, LiaoningAges 18 years+ - NCT06057415Recruiting
Gut nerve stimulation study for high-risk newborns
This study tests whether stimulating the nerves in the gut can help improve digestion in high-risk newborns, specifically those born very early or with a diaphragmatic hernia. It takes place at Amalia Children's Hospital and aims to find a way to help these babies' intestines work better.
NijmegenAges Up to 2 days - NCT06081647Recruiting
Testing a new airway device for endoscopy
This trial tests a special mouth-and-throat device designed to help you breathe easier during a routine endoscopy or colonoscopy. If you are a generally healthy adult scheduled for one of these procedures, you may be able to join.
Nanjing, JiangsuAges 18–60 - NCT06098742Recruiting
Comparing a new liquid antacid to chewable Riopan in healthy adults
This trial tests whether a new liquid antacid (Antareit) works as well as the chewable Riopan tablets in healthy people. It involves a small tube placed through your nose to measure stomach acid before and after taking the medication.
MoscowAges 18–45 - NCT06104241RecruitingEarly Phase 1
Cell therapy for advanced digestive cancers
This trial tests a new cell therapy called BGT007 for people with advanced cancers of the digestive system (esophagus, stomach, pancreas, or colon) that have not responded to standard treatments. The therapy uses your own immune cells, modified to target a protein on your cancer cells.
Xuzhou, JangSuAges 18–70 - NCT06134687Recruiting
New stiffening tube for colon lesion removal
This trial tests a new flexible tube that becomes stiff to help doctors remove large or complex colon lesions during an endoscopic procedure. It may help people with certain types of flat or scarred growths that are harder to remove safely.
Houston, TexasAges 22 years+ - NCT06144905Recruiting
Norwegian Gut Bacteria Study in Anorexia Nervosa
This study looks at gut bacteria in women with anorexia nervosa compared to healthy women. It aims to understand how gut health relates to the condition and recovery.
Ås, ÅsAges 16–50 - NCT06159634Recruiting
Traction vs. No traction for colon polyp removal
This study tests whether using a special 'traction' method makes it easier and safer to remove certain types of colon polyps during a procedure called endoscopic submucosal dissection (ESD). It may help people with large or difficult-to-remove polyps.
Houston, TexasAges 18 years+ - NCT06197334Recruiting
Recording stomach and gut signals with skin sensors
This study uses small sensors placed on your belly to record electrical signals from your stomach and intestines. It may help doctors better understand conditions like Crohn's disease and other digestive issues without using needles or inside-the-body tests.
Vandœuvre-lès-Nancy, CHRU de NancyAges 18 years+ - NCT06200259Recruiting
Reducing Bowel Side Effects in Prostate Cancer Proton Therapy
This study tests a way to reduce stomach and bowel side effects of proton therapy for prostate cancer. It uses special software to place the proton beam more carefully, which may protect nearby organs.
Knoxville, TennesseeAges 18 years+ - NCT06200961Recruiting
Trans-nasal endoscopy for bariatric patients
This study tests a thinner, more comfortable endoscope that goes through the nose instead of the mouth for patients who need an upper GI exam. It may be a gentler option for weight-loss surgery patients.
Boston, MassachusettsAges 18–90 - NCT06202131Recruiting
Blood test for tumor DNA in gastrointestinal cancers
This trial uses a blood test (ctDNA) to look for genetic material from tumors in patients with gastrointestinal cancers. It may help doctors understand and track your cancer better.
Rome, LazioAges 18–85 - NCT06207136Recruiting
Diet and Gut Bacteria in Parkinson's
This study looks at how diet and the bacteria in your gut (microbiome) affect Parkinson's symptoms. You'll work with a coach and take cooking classes to see if changing what you eat can help you feel better.
Vancouver, British ColumbiaAges 40–80
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Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 477 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.