Clinical trials
GBM clinical trials
Below are recruiting gbm clinical trials, each written for real people, not researchers. We’re tracking 86 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07409584Recruiting
Mental health and suicide risk in glioblastoma patients
This study looks at the mental health and thoughts of suicide in people with glioblastoma. It aims to understand these issues better so that patients can get the right support.
BerlinAges 18 years+ - NCT07420543Recruiting
Liquid biopsy during brain tumor surgery with 5-ALA
This trial is studying whether a 'liquid biopsy' (a blood test) can help guide brain tumor surgery. It uses a special dye called 5-ALA to help surgeons see the tumor during surgery, and researchers will look for tumor DNA in the blood to see if it matches what is found in the tumor.
MilanAges 18 years+ - NCT07459101Recruiting
MR-guided radiation therapy for high-grade brain tumors
This study tests a new way to deliver radiation therapy for a type of aggressive brain tumor called glioblastoma or grade 4 astrocytoma. Patients get MRI scans during each treatment so the radiation beam can be adjusted precisely, aiming to improve outcomes.
Toronto, OntarioAges 18 years+ - NCT07485049RecruitingEarly Phase 1
BGB-58067 for newly diagnosed glioblastoma with MTAP deletion
This early-stage trial tests an experimental drug (BGB-58067) for people with a newly diagnosed glioblastoma that has a specific gene deletion (MTAP). It aims to see if the drug can shrink the tumor or slow its growth.
Phoenix, ArizonaAges 18 years+ - NCT07488754Recruiting
Targeted radiation therapy for new glioma (grade 3-4)
This trial tests a new type of targeted radiation therapy for people with high-grade glioma (grade 3 or 4) that has not progressed after standard treatment. The therapy uses a radioactive substance attached to a protein that targets tumor cells, aiming to deliver radiation directly to the cancer.
Warsaw, PolandAges 18–80 - NCT07511725RecruitingPhase 2
Thiotepa spinal injection to prevent glioblastoma spread
This trial tests whether injecting a chemotherapy drug called thiotepa into the fluid around the brain and spine can prevent glioblastoma from spreading in patients whose tumor touches the fluid-filled spaces or who had a leak during surgery.
Hangzhou, ZhejiangAges 18–75 - NCT07627334Recruiting
Personalized drug testing for newly diagnosed brain tumors
This trial tests whether customized drug screening on your tumor cells can help doctors choose the best treatment for you. Your tumor cells will be grown in the lab and tested against different drugs to find what works best, combined with short-course radiation therapy.
Vienna, State of ViennaAges Any age - NCT07648823RecruitingEarly Phase 1
New radioactive treatment for recurrent brain tumors
This early-stage trial tests a new radioactive drug called [177Lu]Lu-XT771 injected directly into the brain cavity after glioblastoma surgery. It measures whether the drug is safe and helps slow tumor regrowth in patients whose cancer has come back after earlier treatments.
Beijing, Beijing MunicipalityAges 18–80 - NCT07417774Enrolling by invitation
Blood test monitoring for glioblastoma treated with chemoradiation and oxygen therapy
This substudy looks at a blood test (liquid biopsy) to track glioblastoma during standard chemoradiation and an experimental oxygen-boosting drug. It aims to see if the test can help monitor the tumor more easily than scans alone.
Tucson, ArizonaAges 18 years+ - NCT07130149Enrolling by invitationPhase 2
Sonodynamic therapy plus chemoradiation for glioblastoma
This trial combines a new therapy (sonodynamic therapy) with standard radiation and chemotherapy for glioblastoma. It aims to see if this approach is safe and how well it works for people who have just been diagnosed and had surgery.
Zhengzhou, HenanAges Up to 75 years - NCT06896110Enrolling by invitationPhase 1
Spinal chemo and immunotherapy for recurrent high-grade glioma
This trial tests a combination of two drugs—azacitidine and nivolumab—given directly into the spinal fluid for people whose high-grade glioma has come back after initial treatment. The goal is to see if this approach can safely target the tumor and slow its growth.
Iowa City, IowaAges 13 years+ - NCT06690216Enrolling by invitationPhase 1/Phase 2
PET scan study for PD-L1 in certain cancers
This trial tests a new PET imaging agent, [18F]AlF-NOTA-PCP2, to detect PD-L1 protein in tumors. It may help guide treatment decisions for people with glioblastoma, head and neck, lung, or esophageal cancer.
Jinan, ShandongAges 18 years+ - NCT06616727Enrolling by invitationPhase 1
CAR-T cell therapy for recurrent glioblastoma
This trial tests a new CAR-T cell treatment (SNC-109) for people with glioblastoma that has come back after initial treatment. The therapy uses your own immune cells, modified in a lab, to try to attack the tumor.
BeijingAges 18 years+ - NCT03914768Enrolling by invitationPhase 1
Immune Cell Vaccine for Brain Tumors
This trial tests a vaccine made from immune cells (dendritic cells) designed to train your body to fight brain tumors like DIPG or glioblastoma. You may qualify if you have one of these tumors, have had standard treatment, and are generally healthy enough for the study.
Shenzhen, GuangdongAges 1–75
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Common questions
- Are there clinical trials for gbm?
- Yes. Clin2 currently lists 86 recruiting gbm studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gbm trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gbm trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.