Clinical trials
Gene Expression clinical trials
Below are recruiting gene expression clinical trials, each written for real people, not researchers. We’re tracking 49 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07169396Recruiting
Genetic study for ovarian cancer treatments
This study looks at genetic changes in ovarian cancer to find possible targeted treatments. It may help you if you have certain types of ovarian cancer and are seeking more personalized care.
Reggio EmiliaAges 18 years+ - NCT07224880Recruiting
Skin tightening and wrinkle treatment study for adults 30-65
This trial tests a micro-coring device called Ellacor® to improve both facial wrinkles and abdominal skin looseness. It is open to people of all skin types and includes those taking certain diabetes/weight-loss medications (GLP-1 agonists).
Dublin, CaliforniaAges 30–65 - NCT00898313Recruiting
Study looks for cancer clues in people at high risk for lung cancer
This study enrolls adults who are being checked for possible lung cancer because of concerning symptoms or a high-risk situation. It aims to find molecular (cell/DNA-related) predictors that may help doctors better recognize lung cancer earlier.
Nashville, TennesseeAges 18 years+ - NCT00985049Recruiting
Study genes from blood flow fluid during aortic valve surgery
This study looks at gene activity in the heart to better understand what is happening during aortic valve surgery. It may help researchers find ways to monitor or improve heart care in the future.
Boston, MassachusettsAges 20 years+ - NCT03291392Recruiting
CUHK stroke biobank for blood, fluid, and tissue samples
This study builds a research bank using samples from people with stroke, their family members, and some people without narrowing in their blood vessels. Your samples help researchers study stroke and related brain and vessel changes.
Hong KongAges 18 years+ - NCT01171872Enrolling by invitation
Study blood and tissue gene signals in bowel inflammation
This study looks at gene activity (what your body’s genes are “doing”) in people with bowel inflammation during endoscopy or bowel surgery. It may help researchers understand inflammatory bowel disease and improve future diagnosis or treatments.
Baltimore, MarylandAges 7 years+ - NCT07512921Recruiting
Gene Expression Study for HPV-Negative Head and Neck Cancer
This study compares gene patterns in tumor tissue and blood samples from patients with HPV-negative head and neck cancer. Understanding these patterns may help doctors better understand the disease and develop better treatments.
MilanAges 18 years+ - NCT07339592Enrolling by invitation
How meal timing affects sleep in medical residents
This study tests whether changing when and what you eat for two weeks can improve sleep quality and how your body's natural clock works. It is for medical residents in Jordan who do not have chronic health issues or sleep disorders.
AmmanAges 25 years+ - NCT06293924Enrolling by invitation
Testing fluid around the heart in recurring pericarditis
This study analyzes pericardial fluid (the fluid around your heart) to understand why pericarditis comes back. If you have pericarditis or other heart fluid buildup requiring drainage, or if you're having heart surgery, you may be able to participate.
Milan, LombardyAges 18 years+ - NCT05521958Enrolling by invitation
Gene activity study in severe leg muscle swelling after fracture
This study looks at gene activity (what genes are “turned on or off”) in the lower leg in people with acute compartment syndrome after a tibia (shin bone) injury. The goal is to better understand what is happening in the body and potentially guide future treatment decisions.
Salt Lake City, UtahAges 18–90 - NCT06332677Recruiting
Study of Suv420h1/2 in liver cells
This study looks at a protein called Suv420h1/2 in liver cells to understand its role in liver disease. It uses stored samples and data from people who already took part in related studies.
MilanAges 18 years+ - NCT06683690Recruiting
Gene study in leprosy patients on treatment
This study looks at certain genes (TGF beta 1) in people with leprosy who are already taking multidrug therapy. It aims to understand how these genes might affect the disease, which could lead to better treatments in the future.
AswānAges 18–50 - NCT07018128Recruiting
Breathing technique for lowering blood pressure in Thai adults
This study tests whether a simple breathing technique (the 4-7-8 method) can help lower blood pressure. It looks at how certain genes might affect the results, and includes people with normal or high blood pressure in eastern Thailand.
MueangChonburi, Changwat Chon BuriAges 18–59 - NCT05302271RecruitingPhase 1
Testing gene therapy for Friedreich’s ataxia heart disease
This Phase 1 trial tests an AAV gene therapy that aims to improve heart problems caused by Friedreich’s ataxia. You may be eligible if you have genetically confirmed Friedreich’s ataxia with measurable heart weakening but still enough heart function to safely receive treatment.
New York, New YorkAges 12–50 - NCT07175922Recruiting
Gene changes in Parkinson's with gut symptoms
This study is looking at how a specific gene (csgA) changes in people with Parkinson's disease, especially those who have had digestive issues. It may help researchers understand the link between gut health and Parkinson's.
LeidenAges 18–80 - NCT03198546RecruitingPhase 1
CAR T therapy for advanced liver cancer with GPC3
This Phase 1 study tests a personalized immune-cell treatment (CAR T cells) for advanced liver cancer that has the GPC3 protein. It aims to see whether these engineered cells can find and kill cancer cells safely and help shrink the cancer.
Guangzhou, GuangdongAges 18–75 - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT03801434RecruitingPhase 2
Ruxolitinib for people with certain eosinophil overgrowth diseases
This trial studies ruxolitinib to treat illnesses where the body makes too many eosinophils (a type of white blood cell) and symptoms or organ damage happen. It may help shrink disease activity when steroids are not enough, cannot be tolerated, or the illness comes back.
Palo Alto, CaliforniaAges 18 years+ - NCT04626674RecruitingPhase 1
Gene therapy safety study for non-ambulatory Duchenne
This Phase 1 trial studies a one-time gene therapy treatment (SRP-9001) to see if it is safe and whether it can produce the needed gene activity in people with Duchenne muscular dystrophy (DMD) who are not walking. It may help researchers understand whether this approach could be useful for DMD patients, especially in later stages.
Little Rock, ArkansasAges 2 years+ - NCT07192432RecruitingPhase 1/Phase 2
Gene therapy for HER2-positive cancer
This trial tests a new gene therapy for people with HER2-positive cancer. It is for two groups: those with advanced cancer that has worsened after treatment, and those with early-stage cancer at high risk of coming back. The goal is to see if the therapy can safely help shrink tumors or prevent return.
Los Angeles, CaliforniaAges 18 years+ - NCT05296564RecruitingPhase 1/Phase 2
TCR cell therapy for NY-ESO-1 positive metastatic cancers
This study tests a customized immune-cell treatment made from your own T cells to attack cancers that have NY-ESO-1. It may help shrink tumors in people with metastatic or hard-to-treat cancer when other treatments have not worked.
JerusalemAges 18–70 - NCT07282717Recruiting
Skin cell study for COL5A mutation and aortic aneurysm
This trial collects a small skin sample from adults with a COL5A gene mutation and thoracic aortic aneurysm. Researchers study the skin cells to better understand the condition and explore potential treatments.
San Donato Milanese, ItalyAges 18 years+ - NCT06783816Recruiting
New immune cell therapy for blood cancers
This study tests a new type of CAR-T cell therapy designed to treat certain blood cancers (like leukemia, lymphoma, or multiple myeloma) that have come back or not responded to standard treatment. The cells are enhanced with IL-15 to help them work better.
Taiyuan, ShanxiAges Any age - NCT04160455Recruiting
Study of GALIG proteins in adults with HIV on or off treatment
This study looks at how “GALIG” gene products affect the body’s internal recycling process (called autophagy) in people living with HIV. It may help researchers understand differences between people on HIV treatment, starting treatment, or not currently taking it.
OrléansAges 18 years+
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Common questions
- Are there clinical trials for gene expression?
- Yes. Clin2 currently lists 49 recruiting gene expression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gene expression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gene expression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.