Clinical trials
Genetics clinical trials
Below are recruiting genetics clinical trials, each written for real people, not researchers. We’re tracking 696 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07251725Recruiting
Genetic study of family-linked lung scarring
This study looks for genetic causes of pulmonary fibrosis that runs in families. You and your affected family member(s) would provide blood samples and health info to help researchers understand why lung scarring happens.
Pavia, LombardyAges 18 years+ - NCT04024774Recruiting
Genetic testing study for rare diseases with an unclear cause
This study looks for a genetic (DNA) explanation for rare diseases when usual genetic testing hasn’t found an answer. It may help by re-analyzing prior results and comparing them with parents’ DNA to better pinpoint the cause.
DijonAges Any age - NCT07249112Recruiting
Genomic study of metabolic fatty liver disease
This study aims to understand the genetic factors behind metabolic fatty liver disease (MASLD) by comparing patients with advanced liver scarring or liver cancer to healthy blood donors. It may help doctors better predict and treat the disease in the future.
Milan, MilanoAges 18–90 - NCT05298722Recruiting
MRI and blood tests to predict if pancreatic surgery is possible
This study looks at MRI scans, computer-extracted imaging features, and blood/“liquid biopsy” tests after FOLFIRINOX chemotherapy to predict whether surgery can fully remove pancreatic cancer. It may help your care team choose the best next step—whether surgery is likely to be possible and how to plan it.
Ghent, East FlandersAges 18 years+ - NCT05779813Recruiting
Family-linked genetic frontotemporal dementia study for teens
This study follows young people ages 9 to 16 who have a close biological family member with genetic frontotemporal dementia (FTD). It aims to better understand this inherited condition and track participants over time. You may complete surveys and thinking/behavior assessments, and you may have brain MRI scans if you choose.
London, OntarioAges 7–17 - NCT07233915Recruiting
Genetic Study of Berry-Shaped Brain Aneurysms
This study looks at the genetic makeup of people with berry-shaped brain aneurysms. It may help researchers understand why some aneurysms rupture and others don't.
Milan, MIAges 18–80 - NCT06257017RecruitingPhase 2
Using DNA tests to guide chemotherapy after bladder cancer surgery
This trial checks if a DNA blood test can help decide who needs extra chemo after bladder or upper urinary tract cancer surgery. It tests whether watching for cancer DNA in the blood can match patients to the right treatment.
Hong Kong, Hong KongAges 18–70 - NCT07227571RecruitingPhase 1
CAR T cells for advanced osteosarcoma
This trial tests whether specially engineered immune cells (called CAR T cells) can attack and kill osteosarcoma tumors that have not responded to standard treatments. It may be an option for children and adults whose cancer has returned or is not controlled by chemotherapy.
Seattle, WashingtonAges 1–75 - NCT06337864Recruiting
Large neutral amino acids for adults with classical PKU
This study tests whether a specific mix of large neutral amino acids (LNAAs) can help adults with classical PKU by lowering phenylalanine levels in the brain. It includes an MRI and PET scan to see how the treatment affects brain activity.
CopenhagenAges 18–50 - NCT06912828Recruiting
Genes and diet for IBS
This trial is studying whether your genes can predict how well a special diet will help your IBS symptoms. If you have moderate to severe IBS and no other diet-related conditions, you may be able to take part.
AthensAges 18–65 - NCT07215416RecruitingPhase 1/Phase 2
Gene therapy for ataxia-telangiectasia with specific ATM mutation
This trial tests a new genetic medicine designed for people with A-T who have a specific ATM gene change. It aims to see if the treatment is safe and if it can improve symptoms.
Boston, MassachusettsAges birth–17 years - NCT07217535Recruiting
Studying the genetics of kidney disease
This study collects DNA and health information from people in the U.S. to better understand how genes may affect kidney disease. Your participation could help researchers find new ways to prevent or treat kidney problems.
Piscataway, New JerseyAges 18 years+ - NCT07217522Recruiting
Genetics of pulmonary hypertension study
This study looks at the genes that may be linked to pulmonary hypertension. By providing a saliva sample and filling out a health survey from home, you can help researchers learn more about this condition.
Piscataway, New JerseyAges 18 years+ - NCT07206095Recruiting
Better diagnosis for inherited red blood cell diseases
This trial aims to improve how doctors diagnose rare inherited anemias, including sickle cell disease and other conditions that destroy red blood cells. It may help if you have a confirmed or suspected diagnosis but need more clarity through advanced testing.
Barcelona, BarcelonaAges Any age - NCT07207564Recruiting
Improving breast cancer risk with pathology, radiology, and genetics
This study looks at tissue, imaging, and genetic information from women who had a non-cancerous breast biopsy to better understand breast cancer risk. It may help improve how we predict and prevent breast cancer in the future.
Jacksonville, FloridaAges 18–100 - NCT06278337Recruiting
Moesin-associated immunodeficiency study
This study looks at a rare immune system condition caused by changes in the MOESIN gene. It aims to better understand the condition and may help develop future treatments.
Bethesda, MarylandAges 4–80 - NCT07185256RecruitingPhase 1/Phase 2
Gene therapy for Best disease retinal trial
This trial tests a gene therapy called OPGx-BEST1 injected under the retina to treat vision loss from Best vitelliform macular dystrophy or a related condition. It may help people with advanced disease who have a specific genetic change in the BEST1 gene.
Los Angeles, CaliforniaAges 18 years+ - NCT07193134RecruitingPhase 1/Phase 2
Gene-modified skin graft for RDEB
This trial tests a new skin graft made with your own cells that have been genetically modified to produce a missing protein (collagen 7). It's for people with RDEB, a severe blistering condition, and aims to see if the graft can heal wounds safely.
Toronto, OntarioAges 7 years+ - NCT06831825RecruitingPhase 1
Gene therapy for heart failure recovery trial
This trial tests a gene therapy injected into the heart to help it recover after a previous heart attack. It may be an option for people with stable heart failure who are not eligible for standard procedures like stents or bypass surgery.
Houston, TexasAges 18–79 - NCT07178704Recruiting
Genes and metabolism after weight loss surgery
This study looks at how your genes and metabolism affect changes in body composition after weight loss surgery. It aims to understand why some people lose more weight or gain muscle differently than others.
Galveston, TexasAges 18–65 - NCT06952413RecruitingPhase 2
Rituximab for chronic fatigue syndrome (ME/CFS) trial
This trial tests if rituximab, a drug that affects the immune system, can help people with ME/CFS. You'll receive the drug in the hospital and be monitored for safety and improvement.
Kodaira, TokyoAges 18–65 - NCT07169396Recruiting
Genetic study for ovarian cancer treatments
This study looks at genetic changes in ovarian cancer to find possible targeted treatments. It may help you if you have certain types of ovarian cancer and are seeking more personalized care.
Reggio EmiliaAges 18 years+ - NCT07174336RecruitingPhase 3
Testing Tersolisib with other treatments for advanced breast cancer
This trial tests a new study drug called Tersolisib combined with other anti-cancer treatments for people with advanced breast cancer that has a specific gene change (PIK3CA). The goal is to see if the combination can help shrink or slow the cancer.
Anchorage, AlaskaAges 18 years+ - NCT07165938Recruiting
Genetics of newborn brain injury study
This study looks for genes that may cause or increase the risk of brain injury in newborns. It may help researchers understand why some babies develop encephalopathy and could lead to better treatments in the future.
Boston, MassachusettsAges Any age
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Common questions
- Are there clinical trials for genetics?
- Yes. Clin2 currently lists 696 recruiting genetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.