Clinical trials
Glioblastoma clinical trials
Below are recruiting glioblastoma clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06598787RecruitingPhase 2
Study of a new drug for recurrent glioblastoma
This trial tests a new drug called BL-B01D1 for people whose glioblastoma has come back after standard treatment. The goal is to see if the drug can help control the tumor.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06607692RecruitingPhase 1/Phase 2
LuPARPed: Targeted radiation plus olaparib for certain childhood cancers
This trial tests a combination of a radioactive drug (Lutathera) and a targeted pill (olaparib) for children and teens whose solid tumors have come back or not responded to treatment and show high levels of a specific receptor (SSTR) on scans. The goal is to see if this two-drug approach can shrink tumors or stop them from growing.
Boadilla del Monte, MadridAges 3 years+ - NCT06622434RecruitingPhase 1/Phase 2
Vaccine for glioblastoma after standard treatment
This trial tests an experimental vaccine for glioblastoma, given after the usual radiation and chemotherapy (temozolomide). The goal is to see if the vaccine helps the immune system fight remaining cancer cells.
Paris, IdfAges 18–75 - NCT06625684Recruiting
Long-term study for glioblastoma patients
This study tracks people with glioblastoma (a type of aggressive brain tumor) over time to understand what affects their health and quality of life. If you take part, you'll fill out online surveys to help researchers learn how to improve care.
Durham, North CarolinaAges 18 years+ - NCT06630260RecruitingPhase 1/Phase 2
Avutometinib and Defactinib for brain tumors
This trial tests two oral drugs, avutometinib and defactinib, in people with aggressive brain tumors like glioblastoma. The goal is to see if this combination can shrink tumors or stop them from growing.
CambridgeAges 16 years+ - NCT06719440Recruiting
Better outcome by shrinking radiation target for glioblastoma
This trial tests a smaller radiation target for newly diagnosed glioblastoma to reduce side effects while keeping treatment effective. It may help patients who are healthy enough for standard chemoradiotherapy.
AalstAges 18 years+ - NCT06757153RecruitingEarly Phase 1
NRG-103 injection for recurrent glioblastoma patients
This trial tests an injection called NRG-103 given directly into the cavity where a recurrent brain tumor was removed. It is for people with glioblastoma that has come back and who have already had standard treatments.
Wuhan, HubeiAges 18 years+ - NCT06773481RecruitingPhase 1
BC008-1A injection for recurrent grade 4 glioma
This trial tests a new injection called BC008-1A for people with a grade 4 glioma (a type of brain cancer) that has come back after standard treatment. The goal is to see if the drug can help control the tumor and improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06782984Recruiting
Testing drugs on your glioblastoma tumor model
This trial uses a lab-grown model of your tumor (called an organoid) to test whether different drugs might work against it. The goal is to find the best treatment for your specific glioblastoma.
Daejeon, Chungcheongnam-doAges Any age - NCT06815029RecruitingPhase 1
Modified immune cells for recurrent brain cancer
This trial tests a new treatment using your own immune cells that are genetically modified to find and attack brain tumor cells. It is for people with a type of brain cancer that has come back after standard therapy.
Duarte, CaliforniaAges 18 years+ - NCT06815432RecruitingPhase 1
CAR T cells for recurrent glioblastoma that makes GPC3
This trial tests a treatment made from your own immune cells, called CAR T cells, which are engineered to find and attack brain tumor cells that have a marker called GPC3. It is for patients whose glioblastoma has come back and who are already scheduled to have another surgery to remove the tumor.
Houston, TexasAges 21–70 - NCT06831526RecruitingEarly Phase 1
Chemoradiation with or without azeliragon for new glioblastoma
This trial tests whether adding the study drug azeliragon to standard radiation and chemotherapy can help people with newly diagnosed glioblastoma. The study will also look at how the tumor responds to the added drug.
St Louis, MissouriAges 18 years+ - NCT06835803RecruitingPhase 2
Intensified radiation for older adults with glioblastoma
This trial tests whether a more focused, stronger dose of radiation can improve outcomes for people 65 and older with newly diagnosed glioblastoma. It compares this approach to standard radiation to see if it's safe and effective.
Boston, MassachusettsAges 65 years+ - NCT06860594RecruitingPhase 1
Triapine plus radiation for recurrent brain tumors
This trial tests whether adding an experimental drug called triapine to a second round of radiation therapy can help treat brain tumors that have come back after initial treatment. It may be a good option for people with recurrent glioblastoma or astrocytoma who meet safety criteria.
Duarte, CaliforniaAges 18 years+ - NCT06910306Recruiting
DaRT alpha radiation for recurrent glioblastoma
This trial tests a device called DaRT that delivers alpha radiation directly to a recurrent glioblastoma tumor. It may help patients who cannot have surgery and have a single, small tumor regrowth.
Scottsdale, ArizonaAges 18–85 - NCT06934889RecruitingPhase 1
Study of ABBV-637 or ABBV-155 with ERAS-801 for recurrent glioblastoma
This trial tests two new drugs (ABBV-637 or ABBV-155) combined with ERAS-801 for people with recurrent glioblastoma (a type of brain cancer). It may help if your tumor has a specific genetic change (EGFR amplification) and you are having surgery to remove part of the tumor.
Los Angeles, CaliforniaAges 18 years+ - NCT07067905RecruitingEarly Phase 1
PET scan test for glioblastoma and kidney cancer
This trial tests a new PET scan tracer called [68Ga]Ga-XT771 to see if it can better detect glioblastoma (a type of brain tumor) and clear cell renal cell carcinoma (a type of kidney cancer). If you have one of these cancers, this scan might help your doctor see the tumor more clearly.
BeijingAges 18 years+ - NCT07093814RecruitingPhase 1/Phase 2
Testing VRT106 injection for recurrent glioblastoma
This trial tests a new injection called VRT106 for people whose glioblastoma (a brain tumor) has come back or is growing. It uses a virus that may help the immune system attack the tumor. This study is for those who have not had a similar virus or gene therapy before.
Hefei, AnhuiAges 18–70 - NCT07111195Recruiting
Using ONCOhabitats to plan brain tumor surgery
This study tests a computer tool called ONCOhabitats that helps doctors plan surgery and treatment for a type of aggressive brain tumor called glioblastoma. By using your MRI scans, the tool may help guide the surgeon to remove as much tumor as possible while sparing healthy brain tissue.
AlicanteAges 18 years+ - NCT07119294Recruiting
FAPI PET/MR imaging for glioblastoma
This study uses a special PET/MR scan to look at certain cells called cancer-associated fibroblasts in glioblastoma brain tumors. It aims to see if this imaging approach can better detect tumors or their recurrence, helping guide treatment decisions.
BrusselsAges 18 years+ - NCT07121842Recruiting
New MRI scan to track glioblastoma growth during treatment
This study is testing a new type of MRI called APTw-CEST to see if it can better detect tumor progression in people with glioblastoma. It may help doctors monitor your tumor more accurately during radiation or chemoradiation therapy.
AmsterdamAges 18 years+ - NCT07134842RecruitingPhase 1
Immunotherapy before standard brain cancer treatment
This trial tests giving the immunotherapy drug ipilimumab before the usual treatment for newly diagnosed glioblastoma (a type of brain cancer). The goal is to see if this approach is safe and possible, and whether it might help the immune system fight the tumor better.
London, Greater LondonAges 18 years+ - NCT07145047RecruitingPhase 1/Phase 2
Oncolytic virus trial for recurrent glioblastoma
This trial tests a virus-based treatment for glioblastoma that has come back after standard therapies. The virus is designed to infect and destroy cancer cells while leaving healthy cells alone.
Mianyang, SichuanAges 18–70 - NCT07145112RecruitingPhase 1
Laser therapy and lomustine for recurrent glioblastoma
This trial combines laser heat therapy (LITT) with the chemotherapy drug lomustine (CCNU) for people whose glioblastoma has returned. It aims to see if the combination is safe and effective.
Sacramento, CaliforniaAges 18 years+
Hear when a new Glioblastoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for glioblastoma?
- Yes. Clin2 currently lists 317 recruiting glioblastoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glioblastoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glioblastoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.