Clinical trials · Massachusetts
Heart Diseases clinical trials in Massachusetts
We’re tracking 44 recruiting heart diseases studies with a site in Massachusetts — including Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT05258981Recruiting
MRI and testing study linking genes and thinking in adults
This study looks at how patterns on brain MRI scans and genes relate to thinking and test performance in adults. It may help researchers better understand long-term brain and cognitive outcomes and how they differ between people with specific early-life heart conditions and healthy controls.
Boston, MassachusettsAges 24–35 - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05786417RecruitingPhase 4
Medication comparison for older adults with stable heart pain
This trial tests which heart medications work best for older adults who have stable angina (predictable chest pain) and multiple other long-term health problems. You may be asked to start or adjust medications and attend regular follow-up visits to see which approach controls symptoms and outcomes.
Boston, MassachusettsAges 65 years+ - NCT06400004RecruitingPhase 3
Lumason infusion vs. bolus for better heart imaging
This trial compares two ways of giving Lumason (an ultrasound contrast agent) to improve images of the left ventricle in people whose initial heart ultrasound was unclear. It may help those with a 'suboptimal' view of the heart's pumping chamber.
Boston, MassachusettsAges 18 years+ - NCT06854458Recruiting
Stress heart MRI for better diagnosis of heart artery disease
This study uses a special stress heart MRI to measure blood flow and find blockages in the arteries that supply your heart. It is for people with chest pain or abnormal EKG results who have risk factors for heart disease, to help doctors diagnose and treat coronary artery disease more accurately.
Boston, MassachusettsAges 35–85 - NCT06642662Enrolling by invitation
Finding biomarkers in children after heart surgery
This study looks at proteins in the blood that may help doctors understand how children are recovering after heart surgery. It enrolls children under age 5 having certain types of heart repairs at Boston Children's Hospital.
Boston, MassachusettsAges 2 days–5 years - NCT02061436Recruiting
Chronic total occlusion procedure registry
This study collects data from patients who are having a procedure to open a completely blocked coronary artery. It may help improve future treatments for this condition.
Boston, MassachusettsAges Any age - NCT05934565Recruiting
Using mindfulness coaching to help people move more
This trial studies a program that uses mindfulness coaching to help people with chronic lung disease (COPD) and/or heart failure (HF) be more physically active. You may benefit if you can safely start exercising and track your steps using a Fitbit.
Boston, MassachusettsAges 40 years+ - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT02860364Recruiting
Checking different cooling levels during part of heart surgery
This trial compares two cooling temperatures during an “aortic hemiarch” operation to see which approach is safer and better for brain protection. It may help guide surgeons on the best cooling strategy for some planned heart surgeries.
Boston, MassachusettsAges 18 years+ - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT06051058Recruiting
App for managing health after hospital discharge
This study tests a smartphone app designed to help people with multiple health conditions manage their care after leaving the hospital. It may help you feel more supported and avoid confusion during the transition from hospital to home.
Boston, MassachusettsAges 55 years+ - NCT06001814Recruiting
Mindfulness program for heart health in older adults with HIV
This study tests whether a mindfulness and behavior change program can help older adults with HIV improve their heart health. It combines phone-based coaching and text messages to reduce stress and manage heart risk factors like high blood pressure and diabetes.
Boston, MassachusettsAges 50 years+ - NCT01733082Recruiting
Mycophenolate pregnancy registry for mothers in the U.S.
This study collects information about pregnancies where a mother took mycophenolate during pregnancy (or stopped within the prior 6 weeks). It aims to better understand pregnancy outcomes and risks so care can be improved for future patients.
Cambridge, MassachusettsAges Any age - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT03954574Recruiting
Check blood flow changes in lungs during exercise testing
This study measures how blood moves through your lungs and heart while you exercise, using standard heart-lung pressure measurements. It may help doctors better understand unexplained breathing trouble or suspected pulmonary hypertension and improve how testing and care are guided.
Boston, MassachusettsAges 18 years+ - NCT07613294RecruitingPhase 3
Testing lepodisiran to reduce heart plaque buildup
This study tests whether a new medicine called lepodisiran can shrink plaque in heart arteries for adults with high Lp(a) (a type of cholesterol linked to heart disease) who have had a heart event or are at serious risk. The trial uses CT scans to monitor changes in your arteries.
Boston, MassachusettsAges 45–80 - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Boston, MassachusettsAges 18–75 - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Boston, MassachusettsAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Boston, MassachusettsAges birth–20 years
Heart Diseases trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting heart diseases studies listed above.
- Brigham and Women's Hospital · 8 studies
- Massachusetts General Hospital · 6 studies
- Beth Israel Deaconess Medical Center · 4 studies
- Boston Children's Hospital · 4 studies
- Brigham and Women's Faulkner Hospital
- Joslin Diabetes Center
- Quintiles Outcome
- VA Boston
What taking part in a heart diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Heart Diseases trials in other states
Common questions
- Are there heart diseases clinical trials in Massachusetts?
- Yes. We're currently tracking 44 recruiting heart diseases studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart diseases study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart diseases studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.