Clinical trials · Minnesota
Heart Diseases clinical trials in Minnesota
We’re tracking 47 recruiting heart diseases studies with a site in Minnesota — including Early Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT07288216RecruitingPhase 2
Switching to KPL-387 alone for well-controlled pericarditis
This study tests whether a new drug, KPL-387, can keep your pericarditis under control as your only treatment, after you have been stable on other medicines. It is for people whose pericarditis is well controlled now but who have had flares in the past.
Rochester, MinnesotaAges 18–80 - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
Rochester, MinnesotaAges 18–75 - NCT07240831Recruiting
Blood pressure monitor trial for people with or without irregular heartbeat
This trial tests a small chest patch that measures blood pressure without a cuff, using a light sensor. It is designed for people who need 24-hour blood pressure monitoring, including those with atrial fibrillation or atrial flutter.
Rochester, MinnesotaAges 18 years+ - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Rochester, MinnesotaAges 18 years+ - NCT05849025Recruiting
MRI heart study using blood-pressure and kidney checks
This study adds an MRI and other measurements to a heart registry to better understand heart function. You might benefit by getting detailed heart and kidney measurements, but you must meet safety and eligibility rules (like blood pressure, BMI, and being off heart medicines).
Rochester, MinnesotaAges 18 years+ - NCT06469918Recruiting
Support community for congenital heart defects
This trial is for people affected by congenital heart defects. It offers a support community (Co-Op) to help you connect, share, and get resources.
Rochester, MinnesotaAges birth+ - NCT06566196Recruiting
Heart exercise testing for congenital heart disease
This study tests how well your heart pumps during exercise while you are undergoing a heart catheter procedure. It may help doctors better understand your heart function and guide your treatment.
Rochester, MinnesotaAges 18 years+ - NCT06693674RecruitingPhase 3
Sacubitril-valsartan for heart health in congenital heart disease
This trial tests if a drug called sacubitril-valsartan can improve heart structure and function in adults with congenital heart disease. You will take the drug and have heart imaging to see changes.
Rochester, MinnesotaAges 18 years+ - NCT07308704Recruiting
Using AI to spot heart muscle disease on echocardiograms
This study at Mayo Clinic is testing an artificial intelligence (AI) tool that analyzes echocardiograms (ultrasound of the heart) to find early signs of four types of heart muscle disease. If the AI flags a high-risk pattern, doctors can learn whether acting on that alert helps catch the condition sooner.
Rochester, MinnesotaAges 18 years+ - NCT05025774Recruiting
Exercise program study for young heart, leukemia, and lung survivors
This study looks at how an exercise program affects fitness and lung function in young people who are survivors of certain conditions (heart transplant, leukemia, or lung disease from prematurity). The goal is to see whether exercise can improve breathing and overall physical function safely.
Minneapolis, MinnesotaAges 8–25 - NCT02061436Recruiting
Chronic total occlusion procedure registry
This study collects data from patients who are having a procedure to open a completely blocked coronary artery. It may help improve future treatments for this condition.
Minneapolis, MinnesotaAges Any age - NCT06195059Recruiting
Heart ultrasound with contrast during exercise to study lungs
This study uses a special ultrasound (echocardiography) with a contrast dye to see how blood flows through your lungs during exercise. It aims to help doctors better understand why patients get short of breath during activity.
Rochester, MinnesotaAges 18 years+ - NCT05100940Recruiting
Study after a heart procedure complication
This trial looks at what happens after complications during or after a heart procedure called coronary angiography or PCI. It may help improve care and outcomes for people who experience a problem during treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT06507657RecruitingEarly Phase 1
Empagliflozin for heart health in older adults
This study tests whether a medication called empagliflozin (a diabetes drug) can improve heart function in older adults with high blood pressure and obesity who are at risk for heart failure but do not have it yet. You would take the pill daily and have heart ultrasounds to check your heart's health.
Minneapolis, MinnesotaAges 60 years+ - NCT07224685Recruiting
Mayo heart & voice health study with phone and watch
This study uses your iPhone and Apple Watch to collect heart and voice data to learn more about cardiovascular health. It may help improve how doctors monitor heart conditions.
Rochester, MinnesotaAges 18 years+ - NCT05100992Recruiting
Bifurcation heart procedure registry for adults
This study is a real-world registry that follows adults who are getting a specific type of heart stent procedure in a forked artery. It helps doctors learn what happens before and after the procedure and improve care.
Minneapolis, MinnesotaAges 18 years+ - NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT03954574Recruiting
Check blood flow changes in lungs during exercise testing
This study measures how blood moves through your lungs and heart while you exercise, using standard heart-lung pressure measurements. It may help doctors better understand unexplained breathing trouble or suspected pulmonary hypertension and improve how testing and care are guided.
Minneapolis, MinnesotaAges 18 years+ - NCT06531824RecruitingPhase 3
Heart and kidney protection study for chronic kidney disease
This study tests a new medicine (BI 690517) combined with empagliflozin to see if it can help protect the heart and kidneys in people with chronic kidney disease. It may slow down kidney disease progression and reduce heart risks.
Minneapolis, MinnesotaAges 18 years+ - NCT07604220Recruiting
Exosome Signatures in Cardiac Sarcoidosis Disease Activity
This study looks for disease markers in tiny particles called exosomes in your blood to better understand cardiac sarcoidosis (a condition where inflammation affects the heart). By measuring these markers alongside your standard heart imaging, researchers hope to find better ways to detect and monitor the disease.
Rochester, MinnesotaAges 18 years+ - NCT07646444Recruiting
Study of OPN Balloon for Opening Hardened Heart Vessel Blockages
This is a follow-up study of patients who have already had a heart procedure using a special balloon (OPN balloon) to open calcified (hardened) blockages in heart arteries. Researchers will review records to see how well this balloon works and how patients recover.
Minneapolis, MinnesotaAges 18 years+ - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Minneapolis, MinnesotaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Minneapolis, MinnesotaAges birth–20 years
Heart Diseases trials by city in Minnesota
Where these studies are running in Minnesota
Institutions with a site for the recruiting heart diseases studies listed above.
- Mayo Clinic · 12 studies
- Minneapolis Heart Institute · 4 studies
- University of Minnesota · 4 studies
- HeartWorks, Inc.
- Investigational Site 028
- Minneapolis VA Health Care System
- Minneapolis VA Healthcare System and University of Minnesota
- University of Minnesota Masonic Cancer Center
What taking part in a heart diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Heart Diseases trials in other states
Common questions
- Are there heart diseases clinical trials in Minnesota?
- Yes. We're currently tracking 47 recruiting heart diseases studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart diseases study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart diseases studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.