Clinical trials
Heart Failure Patients clinical trials
Below are recruiting heart failure patients clinical trials, each written for real people, not researchers. We’re tracking 796 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06312748RecruitingPhase 1
Improving blood vessels in veterans with heart failure
This test is looking at whether certain medications (like statins) can help improve blood vessel health in veterans who have heart failure with preserved pumping function. It may help reduce symptoms and keep you out of the hospital.
Salt Lake City, UtahAges 18 years+ - NCT06645535Enrolling by invitation
Gut Bacteria and Blood Substances in Stiff Heart Failure
This study looks at how bacteria in your gut and certain substances in your blood relate to a type of heart failure called HFpEF (where the heart is stiff and doesn't relax well). It may help doctors understand the condition better and find new ways to treat it.
Naning, JiangsuAges 18 years+ - NCT04822649Recruiting
Assessing exercise capacity in people with heart microvascular problems
This study looks at how well you can exercise and how your body composition relates to tiny blood-vessel problems in the heart. It may help doctors better understand symptoms and function in people who don’t have major blockages in the large heart arteries.
SeoulAges 20–80 - NCT03876223Recruiting
Testing imaging to study heart symptoms without blocked arteries
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
Los Angeles, CaliforniaAges 18 years+ - NCT04600115RecruitingEarly Phase 1
New MRI methods for heart failure with preserved pumping function
This study tests advanced MRI techniques to better understand heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but still doesn't work well. It may help improve diagnosis and treatment for patients with this type of heart failure.
Salt Lake City, UtahAges 18 years+ - NCT04592445Recruiting
Nerve ablation for right-sided symptoms in HFpEF heart failure
This trial tests a procedure to “turn off” the right greater splanchnic nerve to improve symptoms in people with HFpEF (heart failure with preserved pumping function). If successful, it may reduce shortness of breath and fluid congestion in daily life.
Birmingham, AlabamaAges 40 years+ - NCT06907017Recruiting
CorWave left heart pump first-in-human study
This trial tests a new left ventricular assist device (LVAD) for people with advanced heart failure who are not responding to standard treatments and are eligible for a heart transplant. The pump helps the heart circulate blood.
Sydney, New South WalesAges 18–75 - NCT06272734Recruiting
Reprieve system study for hospitalized heart failure
This study tests a device (Reprieve System) to remove extra fluid more safely in heart failure patients while they are hospitalized. It may be a good option if you have fluid buildup and are not too sick from other conditions.
TbilisiAges 18 years+ - NCT06937827Recruiting
Heart failure follow-up clinic after hospital discharge
This program offers phone follow-ups after you leave the hospital to help manage your heart failure. It is for people who had a recent heart failure flare-up but are going straight home without homecare or hospice services.
Brick, New JerseyAges 18–90 - NCT07636343Recruiting
Eccentric Training for Heart Failure Recovery
This trial tests a special type of strength training (eccentric exercise, where muscles lengthen under load) for people with heart failure who have reduced pumping ability. The goal is to improve your exercise capacity and heart function safely.
EdegemAges Any age - NCT07497308Recruiting
GDF-15 levels and early outcomes after LVAD surgery
This trial looks at a blood marker called GDF-15 in people getting a heart pump (LVAD) to see if it can help predict early recovery or complications. It may help doctors better understand how patients will do after surgery.
Antalya, Please Select:Ages 18 years+ - NCT06826534Recruiting
At-home heart rehab for teens with heart failure risk
This study tests if a home-based exercise program using a Fitbit can help teens who had chemotherapy improve their heart and lung fitness. You would exercise at home, track your activity, and have monthly virtual check-ins for 6 months.
Los Angeles, CaliforniaAges birth–21 years - NCT06486649Recruiting
AI tool for diagnosing HFpEF heart failure
This trial is testing a new AI-powered tool to help doctors better diagnose a specific type of heart failure called HFpEF, where the heart pumps normally but doesn't relax properly. It may help you if you have symptoms like shortness of breath or swelling and your heart ultrasound shows normal pumping ability.
Beijing, Beijing MunicipalityAges 18–80 - NCT06770023RecruitingPhase 1
Bridge to lung transplant with ECMO for right heart failure
This study tests a special heart-lung support machine (ECMO) for people waiting for a lung transplant whose heart is failing due to high blood pressure in the lungs. The machine helps rest the heart and lungs until transplant surgery.
Jacksonville, FloridaAges 18–80 - NCT07733960Recruiting
Pacing system study for heart pacing therapy
This trial tests a new pacing system designed to improve how pacemakers work. It may help people who need a pacemaker with left bundle branch area pacing.
Madurai, Tamil NaduAges 18 years+ - NCT07492979Recruiting
Pacemaker placement study for heart failure
This trial compares two types of pacemaker placement to improve heart function in people with heart failure. One method paces the heart's natural conduction system, while the other paces the lower chambers of the heart. The goal is to find which approach works better for heart resynchronization therapy.
AarhusAges 18–99 - NCT04984473Recruiting
Breathing muscle training during heart rehab
This study tests whether breathing muscle training, added to regular heart rehab, can improve how well people with heart failure do day-to-day. It also compares results with healthy volunteers who do not have certain health problems.
Rochester, MinnesotaAges 18 years+ - NCT07293923Recruiting
Magenta Elevate™ study for cardiogenic shock
This trial tests a new heart pump called the Magenta Elevate™ to help people whose heart suddenly stops pumping enough blood (cardiogenic shock). It aims to improve blood flow and reduce strain on the heart.
TbilisiAges 40–89 - NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+ - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT03994874RecruitingPhase 1/Phase 2
Testing fluid removal through the belly in heart-kidney failure
This trial studies a treatment that removes extra fluid through a catheter placed in the abdomen (peritoneal ultrafiltration) for people with “cardio-renal syndrome” (heart and kidney problems together). It may help those who stay congested despite high-dose water pills (diuretics) and have certain heart circulation and fluid signs.
ChietiAges 18 years+ - NCT04162444Recruiting
Aortic valve reconstruction study for children
This trial studies a surgery approach to help fix a narrowed or leaking aortic valve in children. It aims to see how well the reconstructed valve works and how it affects the child’s heart function over time.
MoscowAges 4 weeks–12 years - NCT04191681RecruitingPhase 4
Testing ARNI in people with implanted LVAD devices
This trial studies whether a heart medicine called ARNI (sacubitril-valsartan) is safe and works well for people who have a durable LVAD and moderate-to-severe heart pumping weakness. It may help improve symptoms and outcomes, while carefully checking side effects in this higher-risk group.
Cleveland, OhioAges 18 years+
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Common questions
- Are there clinical trials for heart failure patients?
- Yes. Clin2 currently lists 796 recruiting heart failure patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.