Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06158698RecruitingPhase 3
Colchicine for heart inflammation with arrhythmias
This trial tests whether the drug colchicine can help people with heart muscle inflammation (myocarditis) that also causes abnormal heart rhythms, a weak heart pump, or high stress markers. Colchicine is an anti-inflammatory medicine that might reduce heart damage and improve symptoms.
Naples, CampaniaAges 18 years+ - NCT06162247Recruiting
Registry study for heart patients in intensive care
This study tracks patients with sudden heart problems admitted to a special heart intensive care unit. It helps doctors learn more about these conditions to improve future care.
NaplesAges 18 years+ - NCT06180603Recruiting
Draining lung fluid safely in the ER
This trial tests a better way to drain fluid from around the lung while you are in the emergency department. It can help you breathe easier and find out what is causing the fluid buildup.
Aarhus, Central JutlandAges 18 years+ - NCT06215248Recruiting
Heart function study in leg artery disease patients
This trial uses ultrasound to check how well the heart pumps in people with blocked leg arteries. It aims to find early signs of heart strain that standard tests might miss.
TartuAges 35–85 - NCT06229678RecruitingEarly Phase 1
Ketones and diabetes drug for heart failure with weak pump
This clinical trial looks at whether adding a special diet supplement (ketones) to an SGLT2 inhibitor diabetes drug improves heart function and symptoms in people who have both type 2 diabetes and heart failure with a weakened heart muscle.
San Antonio, TexasAges 18–70 - NCT06272578Recruiting
Heart and kidney health study for chronic disease patients
This study checks how heart and kidney health are related in people with kidney disease, diabetes, high blood pressure, or high cholesterol. It is a single visit with tests to see if certain heart problems are common in these conditions.
Wedding, State of BerlinAges 18 years+ - NCT06291922Recruiting
Home exercise program for LVAD recovery
This study tests a home exercise program using your smartphone after you get a HeartMate 3™ LVAD. It aims to help you get stronger and recover safely at home.
Detroit, MichiganAges 18 years+ - NCT06304857RecruitingPhase 3
Protecting the heart with dapagliflozin during breast cancer treatment
This trial tests if the diabetes drug dapagliflozin can protect the heart in people with breast cancer receiving a type of chemotherapy called anthracyclines. You may be able to join if you are between 18 and 80, have stage I-III breast cancer, and are about to start anthracycline treatment within the next 60 days.
Wroclaw, Lower Silesian VoivodeshipAges 18–80 - NCT06311149Recruiting
Study of LATITUDE heart device monitoring
This trial looks at how well the LATITUDE monitoring system works for people with heart devices. It checks if remote monitoring helps doctors track how your device is doing, so they can spot problems early.
FerraraAges Any age - NCT06316349Recruiting
Leg exercises and electrical stimulation for balloon pump patients
This study tests if leg exercises and mild electrical stimulation can help people who have a balloon pump in their leg artery. It aims to see if these treatments improve strength and recovery while the pump is in place.
São Paulo, São PauloAges 18 years+ - NCT07360158Recruiting
Studying a new implantable heart device (ICD) for heart patients
This study is testing a new type of implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) called the CorSky Family. The goal is to see how well it works for people who need a device to help their heart pump properly and prevent dangerous rhythms.
Graz, StyriaAges 18–99 - NCT06336746Recruiting
Heart function during steep head-down position in robotic surgery
This study looks at how your heart performs during robotic surgery when you are placed in a steep head-down position. It may help doctors better understand how to keep you safe during the procedure.
Karlstad, Värmland CountyAges 18 years+ - NCT06356727Recruiting
Blood vessel health test for heart recovery
This study checks if tiny blood vessel problems in the heart affect how well the heart muscle recovers after being weak. It uses special imaging during a routine heart catheterization to look at these small vessels.
FerraraAges 18–85 - NCT06384963Recruiting
Pacing after bypass for heart failure patients
This trial tests a special pacing therapy that uses your natural breathing rhythm to improve heart function after coronary artery bypass surgery. It may help people with weak heart muscles recover better after surgery.
Adelaide, South AustraliaAges 22 years+ - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT06427304Recruiting
Heart scan study for amyloid protein in older adults
This trial is testing older adults with heart failure to see if a heart condition called cardiac amyloidosis (a buildup of abnormal protein in the heart) is present. If you are 80 or older, have been in the hospital for heart failure in the past year, and have a thickened heart wall, you may be able to join.
Paris, IIe-de-FranceAges 80 years+ - NCT06459934Recruiting
Heart and cardiovascular disease study
This study looks at the health outcomes of people with common heart conditions like coronary artery disease, high blood pressure, heart failure, or cardiomyopathy. It may help researchers understand how these conditions progress and how to better manage them.
Ürümqi, XinjiangAges 18–80 - NCT06436053Recruiting
Pacing to improve heart function study
This study tests a new way to pace the heart to see if it can improve how well the heart pumps. It uses a special Abbott pacemaker to pace a part of the heart called the left bundle branch and adjust the timing to match your natural heart rhythm.
San Donato Milanese, MIAges 18 years+ - NCT06495970Recruiting
Pulmonary artery denervation for heart failure with lung hypertension
This trial tests a procedure called pulmonary artery denervation (PADN) for people with heart failure and a certain type of high blood pressure in the lungs (pulmonary hypertension Group 2). The goal is to see if using a special device called the Gradient Denervation System can help control the high pressures and improve your symptoms.
BadalonaAges 22–85 - NCT06507657RecruitingEarly Phase 1
Empagliflozin for heart health in older adults
This study tests whether a medication called empagliflozin (a diabetes drug) can improve heart function in older adults with high blood pressure and obesity who are at risk for heart failure but do not have it yet. You would take the pill daily and have heart ultrasounds to check your heart's health.
Minneapolis, MinnesotaAges 60 years+ - NCT06510231Recruiting
Breathing muscle training for heart failure with preserved ejection fraction
This study tests whether breathing muscle training can improve exercise capacity and symptoms in people with a type of heart failure called HFpEF. You may qualify if you are already on certain heart medications and are stable enough to exercise.
Rochester, MinnesotaAges 18 years+ - NCT06522594RecruitingPhase 2
Beta-blocker medicine for heart recovery on ECMO
This study tests whether a medicine called esmolol (a beta-blocker) can help your heart recover while you are on a heart-lung machine (V-A ECMO). It is for adults with severe heart failure who are already on certain heart medicines.
Rotterdam, South HollandAges 18 years+ - NCT06542016Recruiting
Heart risk prediction in dialysis patients using a questionnaire
This study looks at how a simple questionnaire (called KCCQ) about your heart health and quality of life can help predict future heart risks for people on dialysis. Researchers want to see if your answers to this questionnaire can help doctors take better care of you.
Guangdong, GuangdongAges 18 years+ - NCT06543173Recruiting
Preventive heart ablation with defibrillator in high-risk patients
This study tests if doing a special heart procedure (catheter ablation) at the same time as implanting a defibrillator (ICD) can prevent dangerous heart rhythms better than the ICD alone. It is for people with a very weak heart pump due to blocked arteries who are getting a first-time ICD.
Copenhagen, Region HAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.