Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06561932Recruiting
Leadless pacemaker for heart failure resynchronization
This trial tests a completely leadless pacemaker (WiSE® CRT) for heart failure patients who need cardiac resynchronization therapy (CRT). It aims to avoid the long-term risks of traditional wires (leads) in the heart.
Birtinya, QueenslandAges 22 years+ - NCT06584266Recruiting
Cardiac imaging registry for atrial fibrillation
This study collects data from heart imaging tests (TEE) in people with atrial fibrillation or atrial flutter. It aims to better understand how these imaging results relate to treatment decisions and outcomes.
BrnoAges 18 years+ - NCT06597331Recruiting
Heart function study for COPD flare-ups
This study looks at how a COPD flare-up might affect the heart in people who haven't had a heart attack or known heart muscle damage before. It uses a simple heart ultrasound to check for stress-related changes.
Gothenburg, Region Västra GötalandAges 18 years+ - NCT06610019Recruiting
Heart imaging study using MRI
This study uses heart MRI scans to learn more about cardiovascular health in adults. If you are 18 or older and have been referred for a heart MRI at Montefiore, you may be able to join.
The Bronx, New YorkAges 18 years+ - NCT06633159Recruiting
MitraClip in Patients With Heart Failure
This study looks at how well a clip (MitraClip G4) fixes a leaky heart valve in people with heart failure. If you are scheduled for this procedure, joining may help doctors learn more about the benefits of the clip.
MoscowAges 18 years+ - NCT06641362Recruiting
Ultra-high frequency ECG for heart timing problems
This study tests a new, more detailed type of ECG (called UHF-ECG) to see if it can better detect uneven electrical timing in the heart. If you are getting your first pacemaker for a slow heart rate or heart failure, this study may help doctors personalize your treatment.
Avondale, ArizonaAges 18 years+ - NCT06642272RecruitingPhase 4
Comparing two diabetes drugs in real-world use
This trial compares two common diabetes medications, empagliflozin and dapagliflozin, to see which works better in everyday practice. It aims to find the best treatment option for patients with type 2 diabetes.
CopenhagenAges 18 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06648733Recruiting
Better medication safety when leaving the hospital for palliative care
This trial studies how to improve medication management when patients with advanced illnesses move from hospital care to home care in Muenster. It aims to make the switch smoother and safer for people who need palliative (comfort-focused) treatment.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06652750Recruiting
5G cloud-based check-up for heart device patients
This study tests whether a 5G-based remote check-up (over the cloud) is safe and effective for people with certain implanted heart devices, like pacemakers. You'll skip your first clinic visit and instead use a video call or remote check to see how your device is doing.
Guangzhou, GuangdongAges 18 years+ - NCT06655376RecruitingPhase 4
Aspirin study for advanced heart failure with a heart pump
This trial tests if taking aspirin along with a standard blood thinner helps people with a HeartMate3 heart pump have fewer bleeding or clotting problems. It is for people who have had their pump for at least 3 months.
Chicago, IllinoisAges 18 years+ - NCT06699446Recruiting
Seamless care from before to after heart surgery
This study is for people who are getting ready for heart surgery and want to follow a program that helps them prepare and recover. It tests a seamless approach from before surgery through rehabilitation, focusing on exercise and support.
Hanover, Lower SaxonyAges 18 years+ - NCT05330221Recruiting
Healthy heart check-in for people at risk of heart failure
This study focuses on adults in the Detroit area who have high blood pressure and other risk factors for heart failure, but have not been diagnosed with heart failure yet. It aims to test an approach to help identify and reduce risk early.
Detroit, MichiganAges 18 years+ - NCT06714344Recruiting
Heart failure therapy support study
This trial tests a new tool to help doctors better manage heart failure treatment. It may be for patients who need IV diuretics for fluid buildup, either in the hospital or at home to avoid hospitalization.
Graz, StyriaAges 18 years+ - NCT06741436Recruiting
Exercise testing after preeclampsia
This study looks at how the heart and blood vessels work after a pregnancy complicated by preeclampsia. It uses exercise testing to see if there are lasting effects, which may help improve long-term heart health monitoring and care.
Nashville, TennesseeAges 18 years+ - NCT06745778Recruiting
Study of heart device signals in patients with left bundle pacing
This study looks at the electrical signals recorded by a special type of pacing lead placed in the heart's left bundle branch. It aims to understand how these signals change over time in people who already have an ICD or CRT-D device.
Wenzhou, ZhejiangAges 18 years+ - NCT06747429Recruiting
High-fat diet for heart failure metabolism
This trial tests whether a high-fat diet can help change how your heart uses energy, potentially improving heart function in people with non-ischemic heart failure.
ParisAges 18 years+ - NCT06765226Recruiting
Study of used Impella heart pumps
This study looks at used Impella heart pumps to see what deposits build up on them during treatment. If you've had an Impella pump for a certain length of time, this study helps doctors learn more about the device.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06779552Recruiting
Study of CardioMEMS System for Heart Failure Patients
This study is looking at how well the CardioMEMS heart monitor works for people with heart failure. The device is already implanted and tracks pressure in your lung artery to help your doctor manage your condition and potentially prevent hospital visits.
Pleasanton, CaliforniaAges 18 years+ - NCT06793371RecruitingPhase 2
Study of CK-4021586 for heart failure with preserved ejection fraction
This trial tests an investigational drug called CK-4021586 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug is safe and well-tolerated. You may qualify if you are 40 to 85, have heart failure symptoms, and have a heart that pumps well but shows signs of strain.
Fairhope, AlabamaAges 40–85 - NCT06811519Recruiting
AI predicts heart function from ultrasound and body scans
This study uses artificial intelligence to predict how well your heart is pumping by looking at your heart ultrasound results and body composition (like body fat and muscle). The goal is to see if adding body composition data makes the AI predictions more accurate.
Yongin, Gyeonggi-doAges 20 years+ - NCT06827314Recruiting
Treating cardiogenic shock with drug and mechanical support
This trial is testing different approaches (medications and mechanical support) to help people with acute heart failure and cardiogenic shock (a sudden drop in the heart's pumping ability). It looks at how well these treatments work in a network of hospitals to improve outcomes.
Bologna, BolognaAges 18 years+ - NCT06849752Recruiting
Early heart failure screening for high-risk patients
This trial checks for early signs of heart failure in people who have multiple risk factors. It will use blood tests, a wearable device, and a handheld ultrasound to find any changes early, so treatment can start quickly.
Cleveland, OhioAges 40 years+ - NCT06862700Recruiting
Less vasopressors for heart shock on ECMO
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.