Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07086131Recruiting
Inspiratory muscle training and cardiac rehab for heart failure
This study tests if adding inspiratory muscle training (exercises for breathing muscles) to standard cardiac rehab helps people with heart failure exercise better. It aims to improve how you feel and function.
Rochester, MinnesotaAges 18 years+ - NCT03994874RecruitingPhase 1/Phase 2
Testing fluid removal through the belly in heart-kidney failure
This trial studies a treatment that removes extra fluid through a catheter placed in the abdomen (peritoneal ultrafiltration) for people with “cardio-renal syndrome” (heart and kidney problems together). It may help those who stay congested despite high-dose water pills (diuretics) and have certain heart circulation and fluid signs.
ChietiAges 18 years+ - NCT07084142Recruiting
Digital aid for ICD decisions
This study is developing a digital tool to help people 70 and older with heart failure decide whether an ICD (a device that prevents dangerous heart rhythms) is right for them. Participants will help test and improve this tool.
San Francisco, CaliforniaAges 60 years+ - NCT06978998Recruiting
Retinal photos to help predict heart failure outcomes
This study tests whether a simple eye photo can help doctors better predict the course of heart failure with reduced pumping strength. If it works, this low-cost test could improve care for people with this condition.
SeoulAges 20 years+ - NCT05759806Recruiting
Testing a device to treat fluid overload in heart failure
This trial studies a device (the Nephronyx System) used in the hospital to treat worsening heart failure with fluid buildup, especially when diuretics (water pills) aren’t working well. It aims to check the device’s safety and whether it performs as expected to help patients get better.
HaifaAges 18 years+ - NCT07052539Recruiting
Kidney disease in heart failure with obesity
This study looks at how kidney disease relates to a type of heart failure (called HFpEF) that often happens in people with obesity. It will help doctors understand this connection better.
Jackson, MississippiAges 18–75 - NCT07054489Recruiting
Genetic guided beta blocker therapy for heart failure
This trial tests whether a genetic test can help doctors choose the best beta blocker for people with heart failure who have mildly reduced pumping function. It aims to improve treatment by matching the drug to your genetic profile.
Detroit, MichiganAges 18–89 - NCT07034599Recruiting
Negative pressure breathing after heart pump implant
This study looks at how a breathing machine that uses negative pressure (like a vacuum) affects the heart and blood flow in people who have a left ventricular assist device (LVAD), a type of heart pump. It may help doctors learn the best way to support breathing after surgery.
KarlsburgAges 18 years+ - NCT05712824Recruiting
Device to measure left-heart pressure in advanced heart failure
This trial tests a wirelessly implanted device that measures pressure in the left upper heart chamber (left atrial pressure) in people with advanced heart failure. By tracking that pressure, researchers hope to better understand disease status and guide care.
Tbilisi, GeorgiaAges 22–88 - NCT07025629RecruitingPhase 3
Dapagliflozin after ICU discharge for heart and kidney health
This study tests if the drug dapagliflozin (a medicine that helps protect the heart and kidneys) can improve recovery in patients who needed a breathing machine or blood pressure support in the ICU. If you qualify, you would take the drug after leaving the ICU to see if it lowers the risk of heart or kidney problems.
ParisAges 18 years+ - NCT06147336Recruiting
Testing the V-Lap system for heart failure monitoring
This trial tests a new device called V-Lap that is placed in the heart to monitor pressure. It may help doctors better manage heart failure and reduce hospital stays. Researchers want to see if it works well in people with mild to moderate heart failure.
Boston, MassachusettsAges 22–88 - NCT06897410Recruiting
Support program after hospital discharge for heart or lung issues
This program offers extra support—like social and home care help—after you leave the hospital for a heart or lung problem. It's designed for people 65 and older who live in the Sant Jaume de Calella Hospital area.
Calella, BarcelonaAges 65 years+ - NCT07022067Recruiting
Smartphone study for chronic coronary syndrome
This study tests if a smartphone app can help people with a chronic heart condition called coronary syndrome. It aims to make care easier and track symptoms at home.
Milan, ItalyAges 18 years+ - NCT07015554Enrolling by invitation
IGF1 levels in women with heart failure
This study looks at a hormone called IGF1 in women with a specific type of heart failure (where the heart pumps normally but is stiff). It may help understand if this hormone is linked to the condition.
Shenzhen, GuangdongAges 18 years+ - NCT07001007Recruiting
Heart vibration test for cardiovascular risk
This trial uses a special device that measures vibrations from your heart to see if it can better predict your risk for heart disease. It's for people already in the larger SCAPIS 2 study who had an echocardiography exam.
StockholmAges 58–72 - NCT07002164Recruiting
Timing of heart artery imaging in NSTEMI with heart failure
This trial looks at the best time to perform a heart catheterization (coronary angiography) in people who have a mild heart attack (NSTEMI) and also develop worsening heart failure symptoms. The goal is to find out if doing the procedure early or later leads to better outcomes.
ChangwonAges 19 years+ - NCT06992284Enrolling by invitation
Heart disease study in Niigata
This study looks at the long-term outlook for people with heart disease in Niigata, Japan. It helps doctors learn more about what affects recovery and health over time.
Niigata, NiigataAges 18 years+ - NCT06973902Recruiting
A study on heart pump therapy and stress echo for advanced heart failure
This trial tests how well a heart stress ultrasound (dobutamine echo) can predict if you will get better from a special heart device called cardiac contractility modulation (CCM). CCM is a pacemaker-like implant for people with advanced heart failure who still have symptoms even with the best medicines. The study will help doctors know which patients benefit the most from this device.
Marcianise, CampaniaAges 18 years+ - NCT06965621RecruitingPhase 2
Heart Nerve Imaging in Heart Failure with ICD
This study uses a special imaging agent (18F-mFBG) to take pictures of the nerves in your heart. It aims to better understand heart function in people with heart failure and an ICD.
Houston, TexasAges 18 years+ - NCT06968533Enrolling by invitation
AI ECG for detecting low heart pumping in older adults
This trial uses an AI tool to analyze your ECG (heart tracing) to detect low pumping function. It may help find hidden heart issues early, especially if you haven't had a recent heart ultrasound.
TaipeiAges 60–85 - NCT06956560Recruiting
Heart Scar Imaging Study for Heart Attack and Failure Patients
This study uses a special imaging agent to see a protein called PDGFRß in the heart, which may help detect scarring (fibrosis) after a heart attack or in heart failure. It aims to improve how we understand and treat heart muscle damage.
UppsalaAges 40–70 - NCT05204693Recruiting
Left-heart patients on stable meds will do study cycling
This trial studies a “cycling instead of pushing” approach for people with left-heart disease who are stable on their heart medicine. The goal is to see if this training/therapy approach is safe and helpful for patients like you.
Zurich, Canton of ZurichAges 18–80 - NCT06648733Recruiting
Better medication safety when leaving the hospital for palliative care
This trial studies how to improve medication management when patients with advanced illnesses move from hospital care to home care in Muenster. It aims to make the switch smoother and safer for people who need palliative (comfort-focused) treatment.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06930495Enrolling by invitation
Weight loss and heart failure with normal pumping strength
This study tests whether weight loss treatments can improve muscle and blood vessel function in people with a specific type of heart failure (HFpEF) who also have obesity. It may help if you have heart failure with a normal ejection fraction and a high BMI.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.