Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05732051RecruitingPhase 2
Nicotinamide riboside to protect the heart during breast cancer chemo
This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.
Lørenskog, AkershusAges 18 years+ - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT05761067Recruiting
Trial for advanced heart weakness with low pumping ability
This study looks at treatment options for adults with significantly reduced heart pumping strength and extensive coronary artery disease. It may help people who are at higher risk due to widespread blocked heart arteries, but eligibility depends on recent heart events and bleeding risk.
GothenburgAges 18 years+ - NCT05793996RecruitingPhase 4
Testing an iron infusion for iron deficiency in HFpEF
This study checks how common iron deficiency is in people with HFpEF (heart failure with preserved pumping strength) and tests whether an iron infusion (Ferinject®) improves health. It targets people with stable heart symptoms and lab results showing low iron stores or related iron deficiency.
TomskAges 18 years+ - NCT05851053Recruiting
Study of heart function years after breast cancer treatment
This study checks how well your heart works long after breast cancer treatment. If you joined the earlier de BLOC-I study, you may be invited for follow-up to understand long-term heart effects.
GroningenAges Any age - NCT05876000Recruiting
Heart pump study for very severe heart failure
This trial tests a left ventricular assist system (a mechanical heart pump for the left side of the heart) in people with very severe heart failure. It may help people who are too sick or not improving despite best available medical treatment.
GrazAges 18–75 - NCT05921279Recruiting
Study heart events in people with breast cancer
This study looks at what heart-related side effects happen in women with breast cancer who are planned to receive chemotherapy. It may help doctors better understand and monitor these risks during treatment.
GalwayAges 18–90 - NCT05934565Recruiting
Using mindfulness coaching to help people move more
This trial studies a program that uses mindfulness coaching to help people with chronic lung disease (COPD) and/or heart failure (HF) be more physically active. You may benefit if you can safely start exercising and track your steps using a Fitbit.
Boston, MassachusettsAges 40 years+ - NCT05971225Recruiting
Testing remote heart monitoring to improve heart outcomes
This study checks whether starting remote wireless heart monitoring for people with heart failure helps improve important heart outcomes. It may help your care team catch warning signs earlier by receiving your heart data from home.
Suwon, Kyonggi DoAges 20 years+ - NCT05972356Recruiting
How heart relaxation affects outcomes in heart surgery
This study looks at whether a measurement of how well the heart relaxes helps predict outcomes after heart surgery. It focuses on patients treated in Amsterdam UMC and uses care data to understand who may be at higher or lower risk.
Amsterdam, North HollandAges 18 years+ - NCT06009718Recruiting
Heart sound and heartbeat analysis study
This study uses artificial intelligence to analyze your heart sounds and heartbeat together to see if this can help understand heart health better. It might lead to easier heart checkups in the future.
ShanghaiAges 18–100 - NCT06039176Recruiting
Learning from the HeartMate 3 device
This study looks at information from the HeartMate 3 LVAD device to learn more about how it works and what it can tell us about the future. It may help people with advanced heart failure who need this specific device.
San Francisco, CaliforniaAges 18–100 - NCT06052475Recruiting
Pacemaker upgrade study for heart failure
This trial is for people with a standard pacemaker that stimulates the right ventricle most of the time. It tests whether a newer type of pacemaker (CRT) can improve heart function and symptoms. If you have a weakened heart (LVEF between 35-50%) and your heart failure has gotten worse, this study may be a good fit.
CambridgeAges 18 years+ - NCT06053580RecruitingPhase 2
Valsartan for pulmonary hypertension: protection study
This trial tests whether a blood pressure medicine called valsartan can help protect the lungs and heart in people with a specific type of pulmonary hypertension (Group 1 PAH). If you have PAH and are stable enough to walk 50 meters, you may be able to join.
Seattle, WashingtonAges 18–80 - NCT06065124Recruiting
Study on weight loss surgery for heart failure with irregular heartbeat
This trial tests if weight loss surgery can help people with heart failure and atrial fibrillation (an irregular heartbeat) improve their heart condition. You may join if you are between 45 and 70, have a BMI of 32 to 40, and have mild to moderate heart failure with preserved pumping function.
Arnhem, GelderlandAges 45–70 - NCT06070428Recruiting
A study on heart failure care after hospital discharge
This trial tests a new care approach for people with heart failure who are in the hospital or emergency room and planning to go home. The goal is to see if it helps them recover and stay healthy.
Detroit, MichiganAges 18 years+ - NCT06078436Recruiting
Early carvedilol for heart failure shock
This trial tests whether starting the heart failure medication carvedilol early, along with standard monitoring, can help people in cardiogenic shock (when the heart can't pump enough blood) due to a weak heart muscle. It aims to see if earlier treatment improves outcomes.
SeoulAges 19 years+ - NCT06081205Recruiting
Heart disease patients in intensive care study
This trial observes patients admitted to the cardiac intensive care unit with acute heart or blood vessel problems. It aims to learn more about their conditions and treatments.
Ioannina, EpirusAges Any age - NCT06090591Recruiting
Heart condition research registry at Dubrava Hospital
This study is a registry that will collect information from people with certain heart conditions (like having a pacemaker, a blood clot, a heart attack, or a valve replacement procedure called TAVI). The goal is to learn more about these conditions and how they are treated.
ZagrebAges 18 years+ - NCT06108076RecruitingEarly Phase 1
Oral ketones for heart failure and diabetes
This study tests whether taking a special oral ketone supplement can help people with both heart failure and diabetes. It looks at both short-term and long-term effects on heart function and blood sugar control.
San Antonio, TexasAges 18–80 - NCT06115096Recruiting
Heart pump blood flow study
This study looks at how blood flows inside your heart while you have a HeartMate 3 heart pump. It aims to understand your heart’s pumping function and may help doctors improve care for people with heart pumps.
Linköping, Östergötland CountyAges 18 years+ - NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
NanjingAges 18–80 - NCT06130059RecruitingPhase 2
Low-dose colchicine for heart failure with inflammation
This trial tests whether a low-dose colchicine (LoDoCo) can help people with heart failure and inflammation feel better and exercise more. It is for adults 50 and older with HFpEF who have signs of inflammation in their blood.
Dallas, TexasAges 50 years+ - NCT06147336Recruiting
Testing the V-Lap system for heart failure monitoring
This trial tests a new device called V-Lap that is placed in the heart to monitor pressure. It may help doctors better manage heart failure and reduce hospital stays. Researchers want to see if it works well in people with mild to moderate heart failure.
Boston, MassachusettsAges 22–88
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.