Clinical trials
Herniated Disc clinical trials
Below are recruiting herniated disc clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06704919Recruiting
Spinal fusion using conduit cages and bone graft putty
This trial tests a new combination of a cage and bone graft putty for spinal fusion surgery. It is for people with degenerative disc disease or a herniated disc in the neck or lower back that needs surgery.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05444751Enrolling by invitationPhase 3
Different pain medicine plans for back surgery
This Phase 3 study compares two combinations of anesthesia and pain medications during lumbar decompression surgery, to see which helps more. It may help patients by aiming for better pain control and recovery using one planned medication approach.
New York, New YorkAges 18–80 - NCT04631133Recruiting
Study of outcomes after surgery using the LISA implant
This study follows adults who get back surgery using the LISA implant to see how well they do afterward and how outcomes change over time. It focuses on people whose long-term, non-surgical care did not relieve low-back pain from specific age-related disc changes.
SilkeborgAges 18 years+ - NCT06415136Enrolling by invitation
Comparing two ways to fuse neck bones after prior surgery
This study tests two methods for adding a new fusion to the level next to a previous neck surgery. It compares using a special plate system versus removing the old plate and putting in a new one.
Southfield, MichiganAges 18 years+ - NCT07171008Recruiting
Ney music for comfort after lumbar disc surgery
This study tests whether listening to ney music can help reduce pain and anxiety after lumbar disc surgery. If you are eligible, you would listen to the music in the hospital, and researchers will measure how you feel.
YalovaAges 18–70 - NCT05035693Recruiting
Follow-up study after a neck disc replacement surgery
This study tracks people after they get the MOVE-C artificial disc in the neck. It checks how well the device works over time and monitors safety and recovery.
ViennaAges 18 years+ - NCT05066711Enrolling by invitation
Study of a neck surgery implant for adults
This trial looks at using a specific implant system during planned front-of-the-neck surgery (C2 to C7) for common neck problems like disc degeneration, injury, or spinal narrowing. It may help doctors compare outcomes with this particular hardware and surgical approach.
Naperville, IllinoisAges 18 years+ - NCT06872918Recruiting
Study of a back manipulation for lumbar disc herniation
This study tests a specific type of back manipulation (Lever Positioning Manipulation) to understand how it affects the discs in the lower spine. It may help people with a herniated disc at L4-L5 find a non-surgical treatment option.
Hangzhou, ZhejiangAges 20–60 - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07184554Recruiting
Nerve block for chronic back pain from disc herniation
This study tests whether a nerve block (called an erector spinae plane block) can help relieve chronic low back and leg pain caused by a herniated disc at L4-L5 or L5-S1, when other treatments have not worked.
AnkaraAges 18–75 - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT07763522Enrolling by invitation
Measuring ankle strength in people with herniated disc weakness
This study tests a new way to measure ankle strength in people who have weakness from a herniated disc in the lower back. The goal is to confirm the measurement tool works well for tracking such weakness.
Helsinki, UusimaaAges 18–65 - NCT06075979Recruiting
Microbes and spine health: a surgical study
This study looks at whether certain microbes (tiny living things) are linked to spine problems like herniated discs or narrow spinal canals. It involves people who need spine surgery, and the findings might help explain why some spines wear out faster.
Jinan, ShandongAges 18–85 - NCT07515287Enrolling by invitation
Pilates for Back Pain Recovery in Middle-Aged Women
This study tests whether Pilates exercises can help women aged 45–60 with chronic lower back disc problems improve their balance, leg strength, and body awareness. Pilates focuses on core stability and controlled movement, which may help restore function lost due to the disc herniation.
Kahramanmaraş, onikişubatAges 45–60 - NCT07722117Recruiting
Reiki for pain after back surgery
This trial tests if Reiki, a gentle hands-on energy therapy, can help reduce pain after lumbar (lower back) surgery. It may offer a drug-free option to help you feel better during recovery.
ParisAges 18 years+ - NCT04182997RecruitingPhase 4
Epidural steroid shot during discectomy for back nerve pain
This trial studies whether giving a steroid medicine into the epidural space during discectomy (back surgery for a herniated disc) helps reduce nerve pain and symptoms. It is mainly for people whose MRI and exam show a single-level lumbar disc herniation after non-surgical treatments didn’t help.
Columbia, MissouriAges 18 years+ - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT04540068Recruiting
Predicting whether a sciatica procedure will work
This study looks for ways to predict how well a specific sciatica procedure (TEI) will help. If you have one-sided nerve pain from the low back, the trial may help personalize treatment so you’re less likely to go through ineffective care.
HaarlemAges 18 years+ - NCT05196503RecruitingPhase 3
PRF gel in spine surgery to reduce nerve pain after herniation
This Phase 3 study tests whether applying a healing material called platelet-rich fibrin (PRF) around the nerve during disc herniation surgery can reduce leftover nerve pain afterward. If you qualify, your team will compare pain intensity between standard care and PRF during the operation.
Strasbourg, Bas-RhinAges 18 years+ - NCT05306665Recruiting
Preventing pain after spine surgery
This study looks at ways to reduce pain after certain spine surgeries. If you’re having one of these procedures, you may be invited to try a pain-prevention approach and help researchers understand what works best.
Chestnut Hill, MassachusettsAges 22 years+ - NCT05963815Recruiting
Spine surgery follow-up using online patient-reported questionnaires
This study looks at recovery after planned (elective) surgery for common lower-back (“lumbar”) spine problems like slipped discs, disc bulges, and narrowing of the spinal canal. You may be asked to complete online questionnaires, and the study uses your answers to understand symptoms and outcomes after surgery.
Rotterdam, South HollandAges 18–80 - NCT06143813Recruiting
Precision treatment for lumbar nerve pain with targeted block
This trial tests if a targeted nerve root injection can improve outcomes for people with persistent leg pain from a compressed nerve in the lower back, with the goal of tailoring surgery more precisely.
Aarhus CAges 18 years+ - NCT06469905Recruiting
Nerve block for pain from herniated disc
This study tests a nerve block injection (called an erector spinae plane block) to see if it helps reduce pain from a herniated disc in the lower back. It may be a good fit if you have ongoing low back pain and have not had spine surgery before.
ElâzığAges 18–65 - NCT06593574Recruiting
Robot-Assisted Back Surgery Study
This study tests a robot that helps surgeons perform a type of back surgery called a laminectomy. It aims to see if the robot makes surgery safer and more effective for people with certain lower spine problems.
BeijingAges 18–80
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Common questions
- Are there clinical trials for herniated disc?
- Yes. Clin2 currently lists 59 recruiting herniated disc studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a herniated disc trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a herniated disc trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.