Clinical trials · Nashville, TN
High blood pressure clinical trials in Nashville
We’re tracking 32 recruiting high blood pressure studies with a site in or near Nashville — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Nashville
- NCT05587712RecruitingPhase 2
Sotatercept trial for children with pulmonary arterial hypertension
This Phase 2 trial tests sotatercept, a medicine that targets the blood-vessel changes in pulmonary arterial hypertension (PAH), in children. It may help improve how well the heart and lungs work by changing the underlying disease process.
Nashville, TennesseeAges 1–17 - NCT06831162Enrolling by invitation
Study on addressing health needs in diabetes care
This study looks at whether connecting people with type 2 diabetes, along with high blood pressure or high cholesterol, to resources for needs like food or housing can improve their health. It uses information from a screening questionnaire and may ask some patients to complete a survey.
Nashville, TennesseeAges 18 years+ - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Nashville, TennesseeAges 18 years+ - NCT06741436Recruiting
Exercise testing after preeclampsia
This study looks at how the heart and blood vessels work after a pregnancy complicated by preeclampsia. It uses exercise testing to see if there are lasting effects, which may help improve long-term heart health monitoring and care.
Nashville, TennesseeAges 18 years+ - NCT07288398RecruitingPhase 3
Levosimendan for exercise limitation in PH-HFpEF
This trial tests if the drug levosimendan can help people with a specific type of pulmonary hypertension (PH-HFpEF) feel less tired and breathless during daily activities, and improve their exercise ability.
Nashville, TennesseeAges 18–85 - NCT07563322Recruiting
Nicotinamide Riboside for Combined Pulmonary Hypertension
This study tests whether nicotinamide riboside (a B-vitamin supplement) can help people with combined pulmonary hypertension—a condition where blood pressure in the lungs is too high. The researchers want to understand how this supplement affects the body's energy metabolism and whether it might reduce symptoms and improve heart function.
Nashville, TennesseeAges 18–85 - NCT07201948Recruiting
Lifestyle program to control high blood pressure
This study tests a team-based lifestyle program to help control or prevent high blood pressure. It focuses on people in Tennessee who are at higher risk and want to make lasting health changes.
Nashville, TennesseeAges 30–80 - NCT07093151Enrolling by invitation
Comparing blood pressure goals after brain tumor surgery
This study looks at two different blood pressure targets after surgery to remove a brain tumor. The goal is to see which target helps patients recover better and have fewer complications.
Nashville, TennesseeAges 18 years+ - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Nashville, TennesseeAges birth–2 weeks - NCT04071327Recruiting
Pulmonary hypertension registry for patient experiences
This trial is a registry that collects health information from people with pulmonary hypertension to better understand the disease and improve care. You may be asked to share details about your diagnosis and visits, especially soon after you start seeing a specialized PH care center.
Nashville, TennesseeAges birth+ - NCT01884051Recruiting
Study of blood and skin changes in pulmonary hypertension
This study looks at how hormones, metabolism, and body signals relate to pulmonary arterial hypertension. You may be eligible if you (or a family member) have idiopathic, inherited, or related pulmonary arterial hypertension, and you can do required blood and other testing.
Nashville, TennesseeAges Up to 90 years - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Nashville, TennesseeAges 18 years+ - NCT04502225Recruiting
Trial of bed head elevation for high blood pressure
This study checks whether raising the head of the bed lowers blood pressure while you’re lying down in people with autonomic failure. It may help find a simple positioning change to reduce risks from high lying blood pressure.
Nashville, TennesseeAges 18–85 - NCT03312556Recruiting
CPAP for high blood pressure when lying down
This trial looks at whether using CPAP (a breathing device) can help control high blood pressure that happens when you lie down, in people with autonomic failure. It’s designed for safety and effectiveness and may improve symptoms and blood pressure control.
Nashville, TennesseeAges 18–85 - NCT02646475RecruitingPhase 1
Study angiotensin medicine to improve metabolism in obesity
This Phase 1 study tests how a medication that affects the body’s angiotensin system (angiotensin-(1-7)) changes metabolism in adults with obesity, insulin resistance, and high blood pressure. It may help researchers understand whether this approach can improve blood sugar/insulin function and related body changes.
Nashville, TennesseeAges 18–60 - NCT05464095Recruiting
Mobile health support for pulmonary arterial hypertension
This study tests whether using a mobile health tool can help people with pulmonary arterial hypertension (PAH) manage their condition in daily life. It’s aimed at adults who are stable on their PAH medicines and can track activity using a wearable device.
Nashville, TennesseeAges 18 years+ - NCT07365332RecruitingPhase 3
IKT-001 for pulmonary arterial hypertension
This study tests a new medicine called IKT-001 for people with pulmonary arterial hypertension (PAH). It aims to see if IKT-001 helps improve exercise ability and other symptoms when added to current PAH therapies.
Nashville, TennesseeAges 18–75 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Nashville, TennesseeAges birth–20 years - NCT06992440RecruitingPhase 2
Empagliflozin for better right heart function in pulmonary hypertension
This trial tests if a diabetes drug can help people with pulmonary arterial hypertension whose right heart function is reduced. Participants take empagliflozin or a placebo for 24 weeks to see if heart function improves.
Nashville, TennesseeAges 18 years+ - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT06297291Recruiting
Long-term safety study for a kidney nerve treatment
This study tests a device that uses ultrasound to calm overactive kidney nerves, which may help lower blood pressure. It is for people with high blood pressure that is hard to control with medication.
Nashville, TennesseeAges 18 years+ - NCT02249923Recruiting
Children with pulmonary hypertension registry in Spanish or English
This registry study collects information from children and families affected by pulmonary hypertension to better understand the condition. It may help researchers track outcomes over time and improve future care.
Nashville, TennesseeAges 1 day–21 years - NCT03042988Recruiting
Heat stress test in people with low nerve control and high blood pressure
This study checks how your body’s blood pressure and stress responses change after being exposed to heat overnight. It’s meant for people with autonomic failure (like certain Parkinson-related or nerve-function conditions) who also have high blood pressure while lying down, which may help researchers understand safer ways to manage it.
Nashville, TennesseeAges 18–80 - NCT04967989RecruitingPhase 3
Laser eye treatment timing for certain glaucoma or eye pressure
This Phase 3 study tests how best to use a laser treatment (SLT) for people with high eye pressure or mild-to-moderate primary open-angle glaucoma. It aims to find the best way to lower eye pressure and protect vision while comparing treatment approaches.
Nashville, TennesseeAges 18 years+
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High blood pressure trials in other cities
Where these studies are running near Nashville
Institutions with a site for the recruiting high blood pressure studies listed above.
- Vanderbilt University Medical Center · 13 studies
- Monroe Carell Jr. Children's Hospital at Vanderbilt · 3 studies
- Ascension Saint Thomas · 2 studies
- Autonomic Dysfunction Center · 2 studies
- Meharry Medical College
- Monroe Carell Jr. Children's Hospital ( Site 1601)
- Research Site
- Tenax Investigational Site
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting high blood pressure studies in Tennessee.
Common questions
- Are there high blood pressure clinical trials near Nashville?
- Yes. We're currently tracking 32 recruiting high blood pressure studies with a site near Nashville, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study near Nashville?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Nashville to take part?
- Not necessarily. These studies have a site near Nashville, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open near Nashville regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.