Clinical trials · Pittsburgh, PA
High blood pressure clinical trials in Pittsburgh
We’re tracking 21 recruiting high blood pressure studies with a site in or near Pittsburgh — including Early Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Pittsburgh
- NCT07041281RecruitingPhase 2
Spironolactone to improve postpartum blood pressure after pregnancy hypertension
This study tests whether the medication spironolactone can help manage high blood pressure after delivery in people who had gestational hypertension or preeclampsia. It may help prevent long-term heart problems.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06274801RecruitingPhase 3
Long-term study of seralutinib for pulmonary arterial hypertension
This trial is for people with pulmonary arterial hypertension (PAH) who have already completed a previous study of the drug seralutinib. It offers continued access to the treatment so doctors can watch its safety and effects over a longer time.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07288398RecruitingPhase 3
Levosimendan for exercise limitation in PH-HFpEF
This trial tests if the drug levosimendan can help people with a specific type of pulmonary hypertension (PH-HFpEF) feel less tired and breathless during daily activities, and improve their exercise ability.
Pittsburgh, PennsylvaniaAges 18–85 - NCT06281665RecruitingPhase 4
Aspirin after preeclampsia: the TAP trial
This trial tests whether taking low-dose aspirin after giving birth can help people who had preeclampsia. It aims to see if aspirin can lower the risk of future heart problems.
Pittsburgh, PennsylvaniaAges 18–55 - NCT06605807Recruiting
Improving medication decisions for older adults in the hospital
This study examines how doctors prescribe medications for older adults with chronic conditions during their hospital stay. The goal is to learn how to make safer and more effective prescribing choices for patients aged 65 and older who are discharged home.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06649110RecruitingPhase 1/Phase 2
A study of LTP001 for healthy people and those with PAH
This study tests an investigational medicine called LTP001 for pulmonary arterial hypertension (PAH). Part A checks safety in healthy volunteers, and Part B tests if it helps people with PAH by improving blood flow in the lungs.
Pittsburgh, PennsylvaniaAges 18–100 - NCT07218029RecruitingPhase 3
Long-term study of sotatercept for PAH
This study is for people who have already taken part in a clinical trial of sotatercept for pulmonary arterial hypertension and done well enough to continue. It tests the long-term safety and effectiveness of staying on sotatercept, an investigational treatment that helps lower blood pressure in the lungs.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07599579Recruiting
Mobile app to manage high blood pressure after pregnancy complications
This study tests a smartphone app to help women who had high blood pressure during pregnancy manage their blood pressure now, 10–20 years later. The goal is to see if the app helps keep blood pressure under control and reduces heart disease risk.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Pittsburgh, PennsylvaniaAges 22 years+ - NCT05546931Recruiting
Mobile health program to help control high blood pressure
This study tests a phone-based (mobile) health program to help people in rural areas better control high blood pressure. It may help you track your readings and follow a plan that supports safer blood pressure over time.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Pittsburgh, PennsylvaniaAges 14–35 - NCT03630211RecruitingPhase 2
Study of stem cell transplant for systemic sclerosis in youth
This Phase 2 study tests whether an “autologous” stem cell transplant—using your own stem cells—can reduce systemic sclerosis disease activity. It is mainly for children, teens, and young adults whose disease did not improve despite standard medicines.
Pittsburgh, PennsylvaniaAges 8–60 - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04071327Recruiting
Pulmonary hypertension registry for patient experiences
This trial is a registry that collects health information from people with pulmonary hypertension to better understand the disease and improve care. You may be asked to share details about your diagnosis and visits, especially soon after you start seeing a specialized PH care center.
Pittsburgh, PennsylvaniaAges birth+ - NCT04930289Enrolling by invitation
Lung transplant registry for better donor lung preservation
This study builds a worldwide database to track and improve how donor lungs are preserved before transplant. Your information may help doctors choose and manage donor lungs more effectively.
Pittsburgh, PennsylvaniaAges Any age - NCT04967989RecruitingPhase 3
Laser eye treatment timing for certain glaucoma or eye pressure
This Phase 3 study tests how best to use a laser treatment (SLT) for people with high eye pressure or mild-to-moderate primary open-angle glaucoma. It aims to find the best way to lower eye pressure and protect vision while comparing treatment approaches.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05452889RecruitingEarly Phase 1
PET scan study in pulmonary hypertension related to scleroderma
This early study uses a PET scan (a type of imaging test) to better understand lung blood-vessel disease in people who have pulmonary hypertension related to scleroderma. It may help researchers find how imaging signals relate to disease and risk.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Bridgeville, PennsylvaniaAges 18 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Uniontown, PennsylvaniaAges 18 years+
Hear when a new High blood pressure trial opens near Pittsburgh, PA
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High blood pressure trials in other cities
Where these studies are running near Pittsburgh
Institutions with a site for the recruiting high blood pressure studies listed above.
- Allegheny General Hospital · 4 studies
- University of Pittsburgh Medical Center · 4 studies
- Magee-Womens Hospital of UPMC · 3 studies
- Preferred Primary Care Physicians, Inc. · 2 studies
- UPMC Presbyterian Hospital · 2 studies
- Clinical Trial Site
- Frontier Clinical Research, LLC
- Heritage Valley Medical Group
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting high blood pressure studies in Pennsylvania.
Common questions
- Are there high blood pressure clinical trials near Pittsburgh?
- Yes. We're currently tracking 21 recruiting high blood pressure studies with a site near Pittsburgh, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study near Pittsburgh?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pittsburgh to take part?
- Not necessarily. These studies have a site near Pittsburgh, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open near Pittsburgh regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.