Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Gainesville, FloridaAges 18–65 - NCT05896579Recruiting
Study heart function during rest and exercise in COPD
This study measures how well the right side of your heart works when you are resting and when you exercise, in people with chronic obstructive pulmonary disease (COPD). It may help researchers better understand COPD-related heart strain and guide future care.
Aurora, ColoradoAges 40 years+ - NCT05881447Recruiting
Study kidney disease patterns in people in Tanzania
This study looks at how common chronic kidney disease is, how it develops over time, and what risk factors are linked to it. It may help improve how kidney disease is recognized and managed in your community.
Bagamoyo, Coast RegionAges 18–99 - NCT05903001Recruiting
Breathing muscle testing to help track lung disease
This study checks whether measurements of your breathing muscle (the diaphragm) can act as a useful “biomarker” to track lung disease. You might be asked to do breathing tests and follow study instructions, and your results may help researchers better monitor COPD, asthma, fibrosis, or pulmonary hypertension.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT05830305Recruiting
Phone app coaching after brain bleed to help blood pressure
This trial tests a mobile health app (WeRISE) to help people who survived an intracerebral hemorrhage (a type of brain bleed) monitor health and manage blood pressure after discharge. It may help you reduce the risk of problems related to high or unstable blood pressure.
Hong KongAges 18–85 - NCT05843500Recruiting
CTEPD and CTEPH registry for long-term blood-clot lung disease
This study builds a registry to learn about people with chronic blood-clot lung disease (CTEPD/CTEPH) and what symptoms and test results look like over time. It may help clinicians better understand the condition and improve future care, since your participation supports data collection rather than a new drug.
San Francisco, CaliforniaAges 18 years+ - NCT05809713Enrolling by invitation
Heart to Heart program to better control high blood pressure
This trial tests a “Heart to Heart” program using regular check-ins (including cell-based monitoring) to help lower high blood pressure. It’s for adults who have had blood pressure that stays too high even with usual care.
Greenville, North CarolinaAges 19 years+ - NCT05746039RecruitingPhase 1/Phase 2
Testing semaglutide for advanced lung disease
This study checks whether semaglutide is safe and feasible for people with advanced lung diseases and higher body weight. It may help by testing a structured treatment approach, but it includes several health and safety limits.
Philadelphia, PennsylvaniaAges 18–80 - NCT05763069Enrolling by invitation
Home monitoring for high-risk pregnancies
This study tests whether checking certain pregnancy warning signs at home (with monitoring technology) can help manage high-risk pregnancies. It may allow closer follow-up while you stay at home, aiming to improve safety and decision-making.
OsloAges 18–50 - NCT05106036Recruiting
Lowering BP targets to prevent memory and thinking decline
This study tests whether setting a lower blood pressure goal can help prevent future memory and thinking problems in older adults. It compares a more intensive blood pressure plan with usual care to see if it better protects the brain over time.
Dallas, TexasAges 70 years+ - NCT05719454Recruiting
Pacemaker-based nerve therapy for high blood pressure
This study tests a new pacemaker programming method (nerve therapy) to help lower blood pressure. It may be an option if you need a dual-chamber pacemaker and your blood pressure stays high despite medicine.
PragueAges 18 years+ - NCT04532489RecruitingEarly Phase 1
PET scan study using a cholesterol-tracking tracer in healthy adults
This early study tests how well a special PET scan tracer can show cholesterol movement in the body. It is for healthy adults who do not have known adrenal problems, and it aims to collect basic imaging safety and dose information.
Ann Arbor, MichiganAges 18 years+ - NCT04546126RecruitingEarly Phase 1
PET scan study tracking cholesterol movement in your body
This early study uses a special PET scan dye to see how cholesterol moves through the body. It is testing how the imaging works in healthy people and in people with adrenal gland hormone secretion problems, to better understand cholesterol handling.
Ann Arbor, MichiganAges 18 years+ - NCT05703386Recruiting
Study MRI changes in small-vessel stroke disease
This study looks at how “small-vessel” changes in the brain develop after an ischemic stroke, using repeated MRI scans. It may help researchers better understand what causes these changes and how to track them over time.
Baltimore, MarylandAges 18 years+ - NCT05707442RecruitingPhase 3
Stent or standard treatment for idiopathic intracranial hypertension
This Phase 3 trial compares putting in a venous sinus stent versus using medicine alone for idiopathic intracranial hypertension (IIH). It aims to see which approach better protects vision and lowers pressure in the brain.
Beijing, Beijing MunicipalityAges 18–60 - NCT05656768Enrolling by invitation
Study how sleep affects nighttime blood pressure
This study looks at how sleep timing and sleep patterns may change your blood pressure at night. If you are already enrolled in the parent research study, you may be invited to take part here.
Birmingham, AlabamaAges 18 years+ - NCT05636397Recruiting
Oral L-citrulline for fragile preterm babies with lung or bowel disease
This trial studies whether an oral medicine called L-citrulline (L-cit) is safe and how it works in very preterm infants. It includes two groups: babies with chronic lung disease (with or without high blood pressure in the lungs) and babies recovering from severe bowel infection (NEC).
Toronto, OntarioAges 1 month–6 months - NCT05556902Recruiting
Testing how epidural spinal cord stimulation may help chronic pain
This study looks at how a device that sends mild signals to the area around your spinal cord may work for long-lasting (chronic) pain. You may be asked to visit a research lab, have blood taken, and follow the study plan so researchers can understand the treatment’s effects.
Birmingham, AlabamaAges 18–89 - NCT05533645Recruiting
Questionnaire study about salt (sodium) intake
This study asks people to report how much salt they eat so researchers can better understand sodium intake in people with high blood pressure and/or advanced kidney disease. It may help improve how salt-related health risks are assessed, though it mainly involves questionnaires and scheduled participation.
LilleAges 18 years+ - NCT05545501Recruiting
Testing a ketone drink and salt in healthy young adults
This study tests how a ketone ester plus salt affects the body in young adults. It likely looks at safety and what changes you can measure after taking it.
Bloomington, IndianaAges 19–39 - NCT05473520RecruitingPhase 3
Doxycycline add-on therapy for lung improvement in tuberculosis
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
Kota Kinabalu, SabahAges 21 years+ - NCT05452889RecruitingEarly Phase 1
PET scan study in pulmonary hypertension related to scleroderma
This early study uses a PET scan (a type of imaging test) to better understand lung blood-vessel disease in people who have pulmonary hypertension related to scleroderma. It may help researchers find how imaging signals relate to disease and risk.
Pittsburgh, PennsylvaniaAges 18–75 - NCT05370014Recruiting
Partner support program for chronic health conditions
This study tests a program that helps patients with chronic health conditions and their care partners work together to improve their health and well-being. If you live in a rural or underserved area in South Carolina and have a condition like diabetes or high blood pressure, you and your support person might be able to join.
Columbia, South CarolinaAges 18 years+ - NCT05411029Recruiting
Study on sleep problems in Somali adults
This study looks at how disrupted sleep shows up in Somali adults without certain health conditions. It may help researchers understand sleep patterns in this community and improve future sleep support.
Rochester, MinnesotaAges 18–70
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.