Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05293756Recruiting
Helping African American adults take blood pressure medicines consistently
This study tests whether a technology-based program (like a smartphone app or videos) can help you take your blood pressure medicines more reliably and improve blood pressure control. It mainly targets adults who need help staying on a multi-drug treatment plan.
Cleveland, OhioAges 50 years+ - NCT04530760Recruiting
Study of breathing problems in people with liver scarring on a ventilator
This study looks at whether people with cirrhosis who are on a breathing machine have increased pressure in the belly and small unnoticed breathing mist (microaspiration). It may help doctors better monitor and prevent breathing complications while patients are being mechanically ventilated.
LilleAges 18–99 - NCT05208450Enrolling by invitation
A program to help Black adults control high blood pressure
This study tests a community-and-clinic support program to help Black adults lower blood pressure and reduce health care disparities. It looks at what support and engagement works best, especially for people whose blood pressure is still above goal.
New York, New YorkAges 18 years+ - NCT05159960Enrolling by invitation
Repeat laser eye treatment study for eligible prior participants
This study is for people who already joined an earlier selective laser eye treatment trial and were able to be followed without needing stronger additional treatments. It looks at the best plan for repeating the laser treatment when appropriate.
Skövde, Västra Götaland CountyAges 18 years+ - NCT05168605Recruiting
Targeted home visits for adults with diabetes and high blood pressure
This study tests whether tailored visits from a care team at your home can improve ongoing health problems from high blood pressure and poorly controlled blood sugar. It may help you by making care easier to follow and more personalized to your daily life.
Dallas, TexasAges 18–60 - NCT05067231Recruiting
UAB heart research biobank for adults 18 and older
This study builds a heart-focused research database by enrolling adults who are willing to provide information and/or samples for future cardiovascular research. It may help researchers study heart disease and develop better treatments over time.
Birmingham, AlabamaAges 18 years+ - NCT05050864Recruiting
Stent versus brain-surgery options for idiopathic pressure
This study compares two treatment approaches for idiopathic intracranial hypertension (high pressure in the brain) that has not improved with usual medical treatment. It may help doctors learn which option works better and is safer for people with specific scan and eye findings.
Paris, ParisAges 18 years+ - NCT05027685Recruiting
Registry for people getting renal nerve ultrasound treatment
This registry follows people who may receive—or recently received—renal denervation using the Paradise ultrasound system. It collects real-world information to help understand safety and effectiveness over time.
ViennaAges 18 years+ - NCT05000515Recruiting
Breathing muscle training to lower blood pressure in postmenopause
This study compares a breathing-based exercise program with regular aerobic exercise to help lower blood pressure and improve blood vessel function in postmenopausal women. It’s mainly for people with mildly elevated resting blood pressure who are not already doing very intense workouts.
Boulder, ColoradoAges 50 years+ - NCT04930289Enrolling by invitation
Lung transplant registry for better donor lung preservation
This study builds a worldwide database to track and improve how donor lungs are preserved before transplant. Your information may help doctors choose and manage donor lungs more effectively.
Phoenix, ArizonaAges Any age - NCT04971720RecruitingPhase 2/Phase 3
Personalized blood pressure timing therapy for some adults
This trial tests whether timing blood pressure medications (based on your natural daily body rhythms) can improve blood pressure control. It’s designed for adults with moderately high blood pressure and focuses on who may benefit from a more precise schedule.
Birmingham, AlabamaAges 18 years+ - NCT04967989RecruitingPhase 3
Laser eye treatment timing for certain glaucoma or eye pressure
This Phase 3 study tests how best to use a laser treatment (SLT) for people with high eye pressure or mild-to-moderate primary open-angle glaucoma. It aims to find the best way to lower eye pressure and protect vision while comparing treatment approaches.
Laguna Hills, CaliforniaAges 18 years+ - NCT04993612Recruiting
Blood test during heart procedure from a wedge position
This study checks whether measuring blood gases from a specific heart “wedge” position during a right heart catheter test gives useful information. It may help doctors understand how blood and oxygen are doing in certain heart and lung conditions.
AachenAges 18–99 - NCT04901884Recruiting
PET/MR scans before and after radiation for heart-lung effects
This study uses special PET/MR imaging before and after radiation treatment to better understand how radiation may affect the heart and lungs. It may help researchers find ways to predict and monitor these side effects using imaging and blood tests.
Toronto, OntarioAges 18 years+ - NCT04439370Recruiting
Blood pressure control study in women with early menopause
This study looks at how the body automatically regulates blood pressure in women who went through menopause earlier than expected. It may help researchers understand whether early menopause affects blood pressure control and related health risks.
Minneapolis, MinnesotaAges 35–70 - NCT04715568RecruitingPhase 4
Testing how smoke exposure affects heart health
This study looks at whether being exposed to secondhand tobacco smoke at work affects heart and blood vessel health. It may help researchers understand which people are at higher risk and how the body responds to that exposure.
San Francisco, CaliforniaAges 40 years+ - NCT04624490RecruitingPhase 1
Lung function MRI using a special gas in volunteers
This Phase 1 study tests a lung scan that uses a special gas and MRI to measure how well your lungs work. It includes healthy volunteers and people with lung disease to see how well the scan works and how safe it is.
Kansas City, KansasAges 3 years+ - NCT04633356RecruitingPhase 1/Phase 2
Measuring pressure in the liver using an endoscopy device
This early-phase study tests a technique to measure blood pressure changes in people with cirrhosis (scarring of the liver). It may help doctors better understand liver circulation problems and guide safer treatment decisions.
Hong Kong, Hong KongAges 18–75 - NCT04505618Recruiting
Eye scan study using special imaging for blood-vessel disease
This study uses a detailed eye scan (optical coherence tomography angiography) to look at how blood vessels in the retina are affected. It may help researchers better understand retinal vascular diseases, though some people will be excluded for safety or image-quality reasons.
Baltimore, MarylandAges 18–99 - NCT04163614Recruiting
Testing blood pressure patterns and fluid removal during dialysis
This study looks at how blood pressure changes during hemodialysis and how much fluid is removed, to see what approach works best for controlling blood pressure. It may help dialysis patients whose blood pressure is often high before or after treatment.
Dallas, TexasAges 18 years+ - NCT04206852Recruiting
Balloon treatment for chronic blood-clot lung vessel disease
This trial tests whether a procedure called balloon pulmonary angioplasty is safe and effective for people with chronic thromboembolic disease in the lungs, especially when surgery isn’t an option. If you have CTEPH, it may help improve lung blood flow and symptoms.
BeijingAges 18 years+ - NCT04031508Enrolling by invitationPhase 2
Omega-3 in an IV for newborns with breathing circulation problems
This trial tests whether giving an omega-3 fat medicine through an IV (along with standard care) improves breathing and blood-flow problems in newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension. It may help reduce strain on the lungs and heart by targeting inflammation and blood-vessel changes.
Mexico City, Mexico CityAges 1 hour–2 weeks - NCT04098354Recruiting
Phone monitoring for high blood pressure in kidney disease
This study tests whether using a home blood pressure monitoring device and phone-based check-ins can help people with high blood pressure and chronic kidney disease manage their health better. You may be asked to record readings and send them regularly during the study.
Edmonton, AlbertAges 18 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.