Clinical trials
Immunosuppression clinical trials
Below are recruiting immunosuppression clinical trials, each written for real people, not researchers. We’re tracking 93 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04745728RecruitingPhase 3
Testing different immune-suppressing treatments for membranous kidney disease
This Phase 3 trial compares different immune-suppressing medicines for idiopathic membranous nephropathy (a kidney disease caused by the immune system). It may help reduce heavy protein leakage in the urine and improve disease control in people who fit specific prior-treatment and lab requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT04843982RecruitingPhase 4
Esketamine to reduce inflammation in septic adults
This trial studies whether esketamine can improve the body’s overactive inflammation during sepsis. Participants are adult ICU patients who are sick enough to need breathing support and have higher severity scores.
Wuhan, HubeiAges 18–80 - NCT04067674Recruiting
Study immune changes in adults with septic shock
This trial looks at how the immune system changes after septic shock in adults in the ICU. It may help doctors better predict or manage complications by studying blood markers a few days after starting treatment.
LyonAges 18 years+ - NCT05089604RecruitingPhase 4
Compare two tacrolimus forms to reduce tremors after liver transplant
This study compares immediate-release versus extended-release tacrolimus (an anti-rejection medicine) to see if one form causes fewer tremors after a first liver transplant. It may help you and your care team choose the best form if tremors are a problem while your body adjusts after transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT05126849RecruitingPhase 2
Stem cell transplant using half-matched donor and cyclophosphamide
This trial tests a stem cell transplant option for children or young adults with severe aplastic anemia that did not respond to prior immune-suppressing treatment. It uses a “half-matched” donor and gives post-transplant cyclophosphamide to help the donor cells work and reduce certain immune reactions.
AmiensAges 3–35 - NCT05242315RecruitingPhase 4
Long-acting tacrolimus after liver transplant
This trial studies whether taking an extended-release form of tacrolimus (a medicine to prevent transplant rejection) after a liver transplant works well for people who are followed at the University of Alberta. It may help simplify dosing and monitor safety and effectiveness after transplant.
Edmonton, AlbertaAges 18 years+ - NCT05321758Recruiting
Stool transplant as first treatment for kids with Crohn’s
This study tests whether transferring healthy gut bacteria from stool into the colon can work as a first treatment for children newly diagnosed with mild-to-moderate Crohn’s disease. It may help reduce inflammation and improve symptoms, and it requires regular colonoscopy to monitor progress.
Wuhan, HubeiAges 2–16 - NCT05415267RecruitingPhase 3
Boosting COVID protection during long-term immune suppression
This study looks at how well a COVID-19 booster works in adults who need long-term medicines that lower immune response. It aims to see whether immunosuppressed people benefit from booster vaccination safely.
Blacktown, New South WalesAges 18 years+ - NCT05510323RecruitingPhase 3
Immunosuppressive treatment for IgA kidney disease in stage 3–4
This trial tests whether immunosuppressive therapy (medicine that calms the immune system) helps people with IgA nephropathy and moderately to severely reduced kidney function. It is intended for adults with confirmed IgA kidney disease who still have significant protein in the urine despite standard blood-pressure kidney protection treatment.
Xi'anAges 18 years+ - NCT05616130Recruiting
Study of abnormal blood immune activation after trauma or elective hip surgery
This study looks at how the body’s blood-related immune system “switches on” in unusual ways after a major injury or elective hip repair. The researchers hope this helps them understand who is at risk for complications and why, by measuring changes in your blood around the time of surgery or hospital treatment.
Gainesville, FloridaAges 18–100 - NCT05621837Recruiting
Biomarker study to guide treatment for several advanced cancers
This study measures how strongly your immune system is being suppressed and uses that information to help personalize cancer treatment. It mainly looks at people with certain advanced cancers and needs tumor tissue and follow-up to check possible immune-related markers.
MilanAges 18–90 - NCT05688774Recruiting
Study of worsening community pneumonia in people with weaker immunity
This study follows how community-acquired pneumonia progresses in hospitalized patients who already have serious health problems or weakened immune systems. The goal is to better understand risk and changes over time, which may help guide future care for people like you.
BerlinAges 18–99 - NCT05860400Recruiting
Testing add-on treatment to calm artery inflammation after heart procedures
This study looks at whether a comprehensive add-on treatment—starting with immune medicine and then a heart procedure when needed—can improve outcomes for people whose coronary artery disease is getting worse quickly. It focuses on cases where inflammation is likely driving new artery blockages or worsening chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05891379Recruiting
Inebilizumab for adults with acute neuromyelitis optica attacks
This trial studies inebilizumab to treat adults with neuromyelitis optica spectrum disorder (NMOSD) who are having an acute attack. It aims to reduce ongoing nerve damage and disability after a recent flare, alongside standard steroid treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06059989RecruitingPhase 3
Testing a new form of infliximab for Crohn's disease
This trial is testing a new way to give infliximab, a treatment for moderate to severe Crohn's disease, as a shot under the skin. It's for people who haven't gotten better with other treatments or need strong medication right away.
Amsterdam, North HollandAges 18–80 - NCT06291025Recruiting
Testing a simpler treatment for immune-mediated TTP
This study is testing a new combination of medicines—immune-suppressing drugs, caplacizumab, and plasma infusions—to treat immune-mediated TTP without standard plasma exchange. It aims to make treatment simpler and potentially safer.
AmiensAges 18 years+ - NCT06346665Recruiting
Transplant infection study for organ and stem cell recipients
This trial follows people who have had a recent organ or stem cell transplant to learn more about infections and how they can be prevented. You may be asked to provide samples and information over time.
MünchenAges Any age - NCT07138898RecruitingPhase 2
Managing immune medications for shoulder replacement in rheumatology patients
This trial tests two ways of managing your immunosuppressant medication around the time of shoulder replacement surgery. The goal is to see if one approach leads to fewer infections while still controlling your rheumatic disease.
New York, New YorkAges 18 years+ - NCT06535568Recruiting
Comparing one vs two blood thinners after heart artery balloon treatment
This trial tests whether taking just one blood thinner (clopidogrel) is as safe and effective as taking two (clopidogrel plus aspirin) for older adults or people at high bleeding risk who have had a drug-coated balloon procedure to open blocked heart arteries.
Milan, MIAges Any age - NCT06544343Recruiting
Remote monitoring for new immunosuppressive therapy
This trial tests whether regular remote check-ins can help manage chronic immunosuppressive medications. If you have an autoimmune condition like rheumatoid arthritis or lupus and are starting a new medicine such as methotrexate or a biologic, you may be eligible.
Perugia, PGAges Any age - NCT06552169RecruitingPhase 2
Treg cell therapy to lower anti-rejection meds after kidney transplant
This trial tests whether adding a special type of immune cell (Treg cells) to standard therapy can help kidney transplant recipients safely take lower doses of anti-rejection medicines. It is for people who are getting a kidney from a living donor.
Phoenix, ArizonaAges 18–65 - NCT06611072Recruiting
Boosting immune response in ovarian cancer surgery
This study examines how to improve the immune system's response during ovarian cancer surgery, potentially helping the body fight the cancer better. It compares patients with ovarian cancer to women having surgery for non-cancerous conditions.
Eindhoven, North BrabantAges 18 years+ - NCT06613880RecruitingPhase 2
Romiplostim with standard therapy for severe aplastic anemia
This trial tests combining a drug called romiplostim (a bone marrow stimulant) with standard immunosuppressive therapy as a first treatment for severe aplastic anemia. It aims to improve blood cell counts and reduce the need for transfusions.
Tianjin, Tianjin MunicipalityAges 12 years+ - NCT06637865RecruitingPhase 1
Safety study of IMP761 in healthy volunteers
This is a first-in-human study testing the safety of an experimental drug called IMP761. It is an antibody that may affect the immune system. Healthy volunteers aged 18 to 55 can participate to help researchers learn about the drug's safety and how the body processes it.
LeidenAges 18–55
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Common questions
- Are there clinical trials for immunosuppression?
- Yes. Clin2 currently lists 93 recruiting immunosuppression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunosuppression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunosuppression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.